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Author: Organizer Committee IPAP18 – Salamanca Publisher: Ediciones Universidad de Salamanca ISBN: 8490129762 Category : Medical Languages : es Pages : 358
Book Description
This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The science that created this advance and its future promise will be discussed. Phillip Allen Sharp is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for “the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence. He works in Institute Professor Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, US. Este libro recoge los resúmenes de la «Innovation in Pharmacy: Advances and Perspectives» que tuvo lugar en Salamanca (España) en septiembre de 2018. La ciencia primitiva de la química y la microbiología fue la fuente de la mayoría de las drogas hasta la revolución de la ingeniería genética a mediados de la década de 1970. Luego, la biotecnología puso a disposición agentes proteínicos novedosos como interferones, factores sanguíneos y anticuerpos monoclonales que han cambiado la farmacia moderna. Durante el año pasado, surgió una nueva farmacia de oligonucleótidos a partir de la ciencia de la expresión génica, como el empalme de ARN y la interferencia de ARN. La capacidad de diseñar agentes terapéuticos a partir de secuencias genómicas transformará el tratamiento de muchas enfermedades. La ciencia que creó este avance y su promesa futura será discutida. Phillip Allen Sharp es un genetista y biólogo molecular estadounidense que co-descubrió el empalme de ARN. Compartió el Premio Nobel de 1993 en Fisiología o Medicina con Richard J. Roberts por "el descubrimiento de que los genes en eucariotas no son cadenas contiguas, sino que contienen intrones, y que el empalme del ARN mensajero para eliminar esos intrones puede ocurrir de diferentes maneras, produciendo diferentes proteínas de la misma secuencia de ADN. Trabaja en el Instituto Profesor Koch Institute for Integrative Cancer Research, Instituto Tecnológico de Massachusetts (MIT), Cambridge, MA, EE. UU.
Author: Organizer Committee IPAP18 – Salamanca Publisher: Ediciones Universidad de Salamanca ISBN: 8490129762 Category : Medical Languages : es Pages : 358
Book Description
This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The science that created this advance and its future promise will be discussed. Phillip Allen Sharp is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for “the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence. He works in Institute Professor Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, US. Este libro recoge los resúmenes de la «Innovation in Pharmacy: Advances and Perspectives» que tuvo lugar en Salamanca (España) en septiembre de 2018. La ciencia primitiva de la química y la microbiología fue la fuente de la mayoría de las drogas hasta la revolución de la ingeniería genética a mediados de la década de 1970. Luego, la biotecnología puso a disposición agentes proteínicos novedosos como interferones, factores sanguíneos y anticuerpos monoclonales que han cambiado la farmacia moderna. Durante el año pasado, surgió una nueva farmacia de oligonucleótidos a partir de la ciencia de la expresión génica, como el empalme de ARN y la interferencia de ARN. La capacidad de diseñar agentes terapéuticos a partir de secuencias genómicas transformará el tratamiento de muchas enfermedades. La ciencia que creó este avance y su promesa futura será discutida. Phillip Allen Sharp es un genetista y biólogo molecular estadounidense que co-descubrió el empalme de ARN. Compartió el Premio Nobel de 1993 en Fisiología o Medicina con Richard J. Roberts por "el descubrimiento de que los genes en eucariotas no son cadenas contiguas, sino que contienen intrones, y que el empalme del ARN mensajero para eliminar esos intrones puede ocurrir de diferentes maneras, produciendo diferentes proteínas de la misma secuencia de ADN. Trabaja en el Instituto Profesor Koch Institute for Integrative Cancer Research, Instituto Tecnológico de Massachusetts (MIT), Cambridge, MA, EE. UU.
Author: Jacques Ganoulis Publisher: John Wiley & Sons ISBN: 3527636668 Category : Science Languages : en Pages : 381
Book Description
Based on an international symposium addressing a key issue in global development, this reference includes both the latest methodologies for and practical examples of effective management of transboundary water resources. Its multidisciplinary approach combines hydrology and environmental science with economic and political approaches, in line with new UNESCO and EU recommendations, which have been formulated and implemented with the active involvement of all three editors. By providing a theoretical framework as well as abundant case studies from southern Europe, Africa, Asia and South America, this handbook provides hydrologists, geologists, engineers and decision-makers with all the knowledge they need for their daily work.
Author: Carmen Llinares-Millán Publisher: Springer Science & Business Media ISBN: 9400777906 Category : Technology & Engineering Languages : en Pages : 528
Book Description
Many areas of knowledge converge in the building industry and therefore research in this field necessarily involves an interdisciplinary approach. Effective research requires strong relation between a broad variety of scientific and technological domains and more conventional construction or craft processes, while also considering advanced management processes, where all the main actors permanently interact. This publication takes an interdisciplinary approach grouping various studies on the building industry chosen from among the works presented for the 2nd International Conference on Construction and Building Research. The papers examine aspects of materials and building systems; construction technology; energy and sustainability; construction management; heritage, refurbishment and conservation. The information contained within these pages may be of interest to researchers and practitioners in construction and building activities from the academic sphere, as well as public and private sectors.
Author: Javier Loidi Publisher: Springer ISBN: 3319548670 Category : Science Languages : en Pages : 644
Book Description
This book provides a compact, up-to-date and detailed overview of the vegetation of the Iberian Peninsula, a highly diverse part of Europe in the Mediterranean area. Written by a group of experienced researchers, the volume includes a first section with general chapters discussing the climate, the biogeography and the flora, and a second section with detailed descriptions of the 14 regional sectors into which the peninsula and Balearic Islands have been divided. A third section explores special features, such as aquatic vegetation, gypsum and dolomite vegetation, coastal vegetation, mountain flora and vegetation, conservation issues and alien flora.
Author: Mònica Colominas Aparicio Publisher: BRILL ISBN: 9004363610 Category : History Languages : en Pages : 411
Book Description
The Religious Polemics of the Muslims of Late Medieval Christian Iberia examines the corpus of polemical literature against the Christians and the Jews of the protected Muslims (Mudejars). Commonly portrayed as communities in cultural and religious decay, Mònica Colominas convincingly proves that the discourses against the Christians and the Jews in Mudejar treatises provided authoritative frameworks of Islamic normativity which helped to legitimize the residence of their communities in the Christian territories. Colominas argues that, while the primary aim of the polemics was to refute the views of their religious opponents, Mudejar treatises were also a tool used to advance Islamic knowledge and to strengthen the government and social cohesion of their communities.
Author: United Cities and Local Governments (UCLG) Publisher: World Bank Publications ISBN: 0821377353 Category : Political Science Languages : en Pages : 350
Book Description
'Decentralization and Local Democracy in the World' constitutes a global reference on decentralization by presenting the contemporary situation of local governments in all regions of the world. The report analyzes local authorities in each continent under three main themes: the evolution of territorial structures; responsibilities and power, management and finances; and local democracy. An additional chapter is dedicated to the governance of large metropolises, where rapid growth presents major challenges, in particular in the fast-developing countries of the South. This report also offers a comparative overview of the different realities concerning the state of decentralization, and how the basic indispensable mechansims for local democracy do, or do not exist in come countries. Relationships between the state and local authorities are evolving toward innovative forms of cooperation. In this context, the role of local authorities in the development of global policies is increasingly recognized. The first Global Observatory on Local Democracy and Decentralization (GOLD) Report is one of the main products of United Cities and Local Governments (UCLG). The GOLD Report is the first of what will be a triennial publication. UCLG represents and defends the interests of local governments on the world stage, regardless of the size of the communities they serve. Headquartered in Barcelona, the organization's stated mission is: To be the united voice and world advocate of democratic local self-government, promoting its values, objectives and interests, through cooperation between local governments, and within the wider international community.
Author: Álvaro Rocha Publisher: Springer ISBN: 3319786059 Category : Technology & Engineering Languages : en Pages : 415
Book Description
This book includes a selection of articles from The 2018 Multidisciplinary International Conference of Research Applied to Defense and Security (MICRADS’18), held in Salinas, Peninsula de Santa Elena, Ecuador, from April 18 to 20, 2018. MICRADS is an international forum for researchers and practitioners to present and discuss the most recent innovations, trends, results, experiences and concerns in the various areas of defense and security, together with their technological development and applications. The main topics covered are: Information and Communication Technology in Education; Computer Vision in Military Applications; Engineering Analysis and Signal Processing; Cybersecurity and Cyberdefense; Maritime Security and Safety; Strategy, Geopolitics and Oceanopolitics; Defense planning; Leadership (e-leadership); Defense Economics; Defense Logistics; Health Informatics in Military Applications; Simulation in Military Applications; Computer Networks, Mobility and Pervasive Systems; Military Marketing; Military Physical Training; Assistive Devices and Wearable Technology; Naval and Military Engineering; Weapons and Combat Systems; Operational Oceanography. The book is aimed at all those dealing with defense and security issues, including practitioners, researchers and teachers as well as undergraduate, graduate, master’s and doctorate students.
Author: Ricardo Rozzi Publisher: Springer ISBN: 3319121332 Category : Science Languages : en Pages : 464
Book Description
This book advances Earth Stewardship toward a planetary scale, presenting a range of ecological worldviews, practices, and institutions in different parts of the world and to use them as the basis for considering what we could learn from one another, and what we could do together. Today, inter-hemispheric, intercultural, and transdisciplinary collaborations for Earth Stewardship are an imperative. Chapters document pathways that are being forged by socio-ecological research networks, religious alliances, policy actions, environmental citizenship and participation, and new forms of conservation, based on both traditional and contemporary ecological knowledge and values. “The Earth Stewardship Initiative of the Ecological Society of America fosters practices to provide a stable basis for civilization in the future. Biocultural ethic emphasizes that we are co-inhabitants in the natural world; no matter how complex our inventions may become” (Peter Raven).
Author: Organizer Committee IPAP18 – Salamanca
Author: Organizer Committee IPAP18 – Salamanca
Author: Jacques Ganoulis
Author: Carmen Llinares-Millán
Author: Juan Facundo Riaño
Author: Javier Loidi
Author: Mònica Colominas Aparicio
Author: John A. Crow
Author: United Cities and Local Governments (UCLG)
Author: Álvaro Rocha
Author: Ricardo Rozzi