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Author: Ram Prasad Publisher: Springer Nature ISBN: 3030403378 Category : Science Languages : en Pages : 461
Book Description
In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.
Author: Ram Prasad Publisher: Springer Nature ISBN: 3030403378 Category : Science Languages : en Pages : 461
Book Description
In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.
Author: Anton Ficai Publisher: Elsevier ISBN: 0323461514 Category : Science Languages : en Pages : 724
Book Description
Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area
Author: R. Navanietha Krishnaraj Publisher: John Wiley & Sons ISBN: 1119617197 Category : Technology & Engineering Languages : en Pages : 420
Book Description
MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.
Author: Sougata Ghosh Publisher: Elsevier ISBN: 0128231157 Category : Technology & Engineering Languages : en Pages : 362
Book Description
Nanobiotechnology: Microbes and Plant Assisted Synthesis of Nanoparticles, Mechanisms and Applications covers in detail the green synthesis of nanostructures of tailor-made size, shape and physico-chemical and opto-electronic properties. The rationale behind the selection of bacteria, cyanobacteria, algae, fungi, virus and medicinal plants for the synthesis of biologically active exotic nanoparticles for biomedical applications is also part of this book. It also explores metal recovery, bioconversion, detoxification and removal of heavy metals using nanobiotechnology and discusses the potential of nanobiotechnology to address environmental pollution and toxicity. The book further covers the economic and commercial aspects of such green nanobiotechnology initiatives, its current status in intellectual property rights like patents filed so far globally, technology transfers, and market potential. This information enables one to decipher the scope of biogenic nanoparticles and its prospects. - Provides an overview on the general and applied aspects on nanotechnology - Gives the scope of exploring bacteria, fungi, algae, virus and medicinal plants for the synthesis of exotic nanoparticles - Furnishes a comprehensive report on the underlying molecular mechanisms behind the biosynthesis of nanoparticles - Outlines sustainable alternative strategies of bioremediation of heavy metals, metal recovery, detoxification and bioconversion using nanobiotechnology - Explores the promises of patenting, technology transfer and commercialization potential of biogenic nanoparticles
Author: Sadik Dincer Publisher: BoD – Books on Demand ISBN: 1789858992 Category : Science Languages : en Pages : 362
Book Description
This book examines biofilms in nature. Organized into four parts, this book addresses biofilms in wastewater treatment, inhibition of biofilm formation, biofilms and infection, and ecology of biofilms. It is designed for clinicians, researchers, and industry professionals in the fields of microbiology, biotechnology, ecology, and medicine as well as graduate and postgraduate students.
Author: Mahendra Rai Publisher: CRC Press ISBN: 1000196488 Category : Science Languages : en Pages : 353
Book Description
This book provides an account of the biogenic synthesis of nanomaterials by using different microorganisms. The chapters are focused on the biosynthesis of various metal and metal oxide nanosized materials by using bacteria, actinomycetes, fungi, and algae, including mechanisms of microbial synthesis. Other chapters summarize recent developments of microbial-based nanostructures for the management of food-borne pathogens, plant pathogenic fungi, as nutrients, and biomedical applications. Microorganisms are discussed not only as biofactories for the synthesis of nanomaterials but also as removal agents of toxic metals from the environment. Exposure sources and ecotoxicity of microbially synthesized nanoparticles are also discussed.
Author: Naga Raju Maddela Publisher: Springer Nature ISBN: 9811599165 Category : Science Languages : en Pages : 414
Book Description
Combined fields of Microbiology and Nanotechnology have been most successful in providing novel solutions for protecting the health of humans and environment. This book covers the implications of nano-strategies to combat bacterial pathogens, applications of nanotechniques in microbiology, and innovative advances in the area of medical microbiology. Contents are divided into three sections -- Nanoscience in controlling bacterial pathogens, Nanoscience in Microbiology, Medical Microbiology. This volume is going to provide timely information about the technological advances of Nanoscience in the domain of Microbiology, with a special emphasis on Pathobiology. The book is a useful read for students and researchers in microbiology, nanotechnology and medical microbiology.
Author: Daniel L. Fedlheim Publisher: CRC Press ISBN: 9780585404394 Category : Science Languages : en Pages : 348
Book Description
A state-of-the-art reference, Metal Nanoparticles offers the latest research on the synthesis, characterization, and applications of nanoparticles. Following an introduction of structural, optical, electronic, and electrochemical properties of nanoparticles, the book elaborates on nanoclusters, hyper-Raleigh scattering, nanoarrays, and several applications including single electron devices, chemical sensors, biomolecule sensors, and DNA detection. The text emphasizes how size, shape, and surface chemistry affect particle performance throughout. Topics include synthesis and formation of nanoclusters, nanosphere lithography, modeling of nanoparticle optical properties, and biomolecule sensors.
Author: Avinash P. Ingle Publisher: John Wiley & Sons ISBN: 1119745853 Category : Science Languages : en Pages : 378
Book Description
Discover the role of nanotechnology in promoting plant growth and protection through the management of microbial pathogens In Nanotechnology in Plant Growth Promotion and Protection, distinguished researcher and author Dr. Avinash P. Ingle delivers a rigorous and insightful collection of some of the latest developments in nanotechnology particularly related to plant growth promotion and protection. The book focuses broadly on the role played by nanotechnology in growth promotion of plants and their protection through the management of different microbial pathogens. You’ll learn about a wide variety of topics, including the role of nanomaterials in sustainable agriculture, how nano-fertilizers behave as soil feed, and the dual role of nanoparticles in plant growth promotion and phytopathogen management. You’ll also discover why nanotechnology has the potential to revolutionize the current agricultural landscape through the development of nano-based products, like plant growth promoters, nano-fertilizers, nano-pesticides, and nano-insecticides. Find out why nano-based products promise to be a cost-effective, economically viable, and eco-friendly approach to tackling some of the most intractable problems in agriculture today. You’ll also benefit from the inclusion of: A thorough introduction to the prospects and impacts of using nanotechnology to promote the growth of plants and control plant diseases An exploration of the effects of titanium dioxide nanomaterials on plant growth and the emerging applications of zinc-based nanoparticles in plant growth promotion Practical discussions of nano-fertilizer in enhancing the production potentials of crops and the potential applications of nanotechnology in plant nutrition and protection for sustainable agriculture A concise treatment of nanotechnology in seed science and soil feed Toxicological concerns of nanomaterials used in agriculture Perfect for undergraduate, graduate, and research students of nanotechnology, agriculture, plant science, plant physiology, and crops, Nanotechnology in Plant Growth Promotion and Protection will also earn a place in the libraries of professors and researchers in these areas, as well as regulators and policymakers.
Author: Sahra Kırmusaoğlu Publisher: BoD – Books on Demand ISBN: 1789231604 Category : Science Languages : en Pages : 156
Book Description
Bacterial pathogens have been becoming the main problem in hospital and community-acquired infections. It is hard to treat the strains that are resistant to antibiotics, due to the causing recurrent and untreatable infections. In recent years, the combination treatments and the novel technologies have been preferred to overcome the emergence of antibacterial resistance of pathogens. In this book, examples of pathogenesis by clinical cases, control by antibiotics and bioactive antimicrobials, control by novel technologies with the collection of up-to-date researches and reviews are presented. This book can be useful for researchers interested in antibacterials, bioactive compounds, and novel technologies.
Author: Ram Prasad
Author: Ram Prasad
Author: Anton Ficai
Author: R. Navanietha Krishnaraj
Author: Sougata Ghosh
Author: Sadik Dincer
Author: Mahendra Rai
Author: Naga Raju Maddela
Author: Daniel L. Fedlheim
Author: Avinash P. Ingle
Author: Sahra Kırmusaoğlu