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Author: Martin J. D'Souza Publisher: CRC Press ISBN: 9814613312 Category : Medical Languages : en Pages : 239
Book Description
Recent years have seen the development of novel technologies that use nanoparticles and microparticles to deliver vaccines by the oral and microneedle-based transdermal route of administration. These new technologies enable the formulation of vaccine particles containing vaccine antigens, without loss of their biological activity during the formula
Author: Martin J. D'Souza Publisher: CRC Press ISBN: 9814613312 Category : Medical Languages : en Pages : 239
Book Description
Recent years have seen the development of novel technologies that use nanoparticles and microparticles to deliver vaccines by the oral and microneedle-based transdermal route of administration. These new technologies enable the formulation of vaccine particles containing vaccine antigens, without loss of their biological activity during the formula
Author: Manmohan Singh Publisher: John Wiley & Sons ISBN: 0470134925 Category : Science Languages : en Pages : 470
Book Description
The authoritative reference on recent developments in vaccinology New technologies, including recombinant protein and DNA, have sparked phenomenal progress in vaccine development and delivery systems. This unique resource brings scientists up to date on recent advances and provides the information they need to select candidate adjuvants. With chapters written by leading experts in their fields, Vaccine Adjuvants and Delivery Systems: * Provides a comprehensive overview of the rapidly evolving field and developing formulation methods * Covers cutting-edge technologies and gives the current status of adjuvants in clinical trials and those still in the pre-clinical stage * Includes detailed information on specific vaccine adjuvants, including MF59, TLR4 agonists, new iscoms, cytokines, polyphosphazenes, and more * Provides a historical perspective on the development of vaccine adjuvants and discusses the mechanisms of adjuvant actions * Covers some novel adjuvants and delivery systems and the safety evaluation of adjuvants A great reference for researchers, scientists, and students in vaccinology, biotechnology, immunology, and molecular biology, this resource is also valuable for researchers and scientists in veterinary medicine who work to prevent diseases in animals.
Author: Deepak Thassu Publisher: CRC Press ISBN: 1420008447 Category : Medical Languages : en Pages : 373
Book Description
With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e
Author: Mariusz Skwarczynski Publisher: William Andrew ISBN: 0323400299 Category : Medical Languages : en Pages : 462
Book Description
This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. - Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development - Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development - Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines
Author: Shigeru Kunugi Publisher: Springer Science & Business Media ISBN: 3642278558 Category : Technology & Engineering Languages : en Pages : 290
Book Description
Functional Polymer Conjugates for Medicinal Nucleic Acid Delivery, by Ernst Wagner Biodegradable Nanoparticles as Vaccine Adjuvants and Delivery Systems: Regulation of Immune Responses by Nanoparticle-Based Vaccine, by Takami Akagi, Masanori Baba and Mitsuru Akashi Biodegradable Polymeric Assemblies for Biomedical Materials, by Yuichi Ohya, Akihiro Takahashi and Koji Nagahama PEGylation Technology in Nanomedicine, by Yutaka Ikeda and Yukio Nagasaki Cytocompatible Hydrogel Composed of Phospholipid Polymers for Regulation of Cell Functions, by Kazuhiko Ishihara, Yan Xu and Tomohiro Konno Design of Biointerfaces for Regenerative Medicine, by Yusuke Arima, Koichi Kato, Yuji Teramura and Hiroo Iwata Advances in Tissue Engineering Approaches to Treatment of Intervertebral Disc Degeneration: Cells and Polymeric Scaffolds for Nucleus Pulposus Regeneration, by Jeremy J. Mercuri and Dan T. Simionescu Functionalized Biocompatible Nanoparticles for Site-Specific Imaging and Therapeutics, by Ranu K. Dutta, Prashant K. Sharma, Hisatoshi Kobayashi and Avinash C. Pandey
Author: Deepak Thassu Publisher: CRC Press ISBN: 9780367453114 Category : Languages : en Pages : 376
Book Description
This expertly written guide addresses the scientific methodologies, formulation, processing, applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS, including lipid nanoparticles for dermal applications, nanocarriers for the treatment of restenosis, ocular, central nervous system, and gastrointestinal applications, and use as an adjuvant for vaccine development.
Author: Harvinder Singh Gill Publisher: Springer Nature ISBN: 3030850676 Category : Medical Languages : en Pages : 140
Book Description
This book introduces nanoparticles as a powerful platform for vaccine design. Current challenges in vaccine development are discussed and the unique advantages nanoparticles provide in overcoming these challenges are explored. The authors offer fascinating insights into the immunological assets of using nanoparticles as delivery vehicles or adjuvants and present different materials that are being used in nanoparticle-based vaccine development, covering peptides, proteins, polymers, virus-like particles, and liposomes. Its contemporary research insights and practical examples for applications make this volume an inspiring read for researchers and clinicians in vaccinology and immunology. Chapter "Liposome Formulations as Adjuvants for Vaccines" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author: Vivek Chavda Publisher: John Wiley & Sons ISBN: 1394174683 Category : Science Languages : en Pages : 532
Book Description
NANOCARRIER VACCINES This book details the benefits, restrictions, and types of nanoparticles used in the creation of vaccines for the treatment and prevention of illnesses. In nanomedicine and nano-delivery systems, materials in the nanoscale range are used as diagnostic instruments or to administer therapeutic compounds to particular targeted regions in a controlled manner. By delivering precise medications to specified locations and targets, nanotechnology provides several advantages in treating chronic human illnesses. The use of nanomedicine (including chemotherapeutic medicines, biological agents, immunotherapeutic agents, etc.) in the treatment of various diseases has recently seen many notable applications. This book aims to be a single source material for understanding all the current and novel advancements in the field of nanotechnology. In this groundbreaking book the reader will find: biodegradable and non-biodegradable formulations and properties such as size, shape, charge, inertness, efficacy, morphology, and more; show how different nanoparticles, such as lipid-based, viral vector-based, and metal, uphold very significant properties individually, suggesting applicability in various management tactics; examines how genetic information-carrying entities are becoming the norm for eradicating some diseases; gathers an exhaustive amount of information on routes of administration such as the oral route, mucosal immunity, intramuscular, subcutaneous, and intradermal; explores the legal regulations for nanotechnology-based approaches. Audience Researchers and pharmacy students in biomedical engineering and chemical engineering, biotechnology, as well as pharmaceutical and biopharmaceutical industry engineers working in drug discovery, chemical biology, computational chemistry, medicinal chemistry, and bioinformatics.
Author: Martin J. D'Souza
Author: Martin J. D'Souza
Author: Manmohan Singh
Author: Deepak Thassu
Author: Mariusz Skwarczynski
Author: Shigeru Kunugi
Author: Rajko Reljic
Author: Deepak Thassu
Author: Rinku Singh
Author: Harvinder Singh Gill
Author: Vivek Chavda