Nanomaterials: Evolution and Advancement Towards Therapeutic Drug Delivery (Part I) PDF Download

Author: Surendra Nimesh
Publisher: Bentham Science Publishers
ISBN: 1681087820
Category : Science
Languages : en
Pages : 316

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Book Description
The development of a vector for the delivery of therapeutic drugs in a controlled and targeted fashion is still a major challenge in the treatment of many diseases. The conventional application of drugs may lead to many limitations including poor distribution, limited effectiveness, lack of selectivity and dose dependent toxicity. An efficient drug delivery system can address these problems. Recent nanotechnology advancements in the biomedical field have the potential to meet these challenges in developing drug delivery systems. Nanomaterials are changing the biomedical platform in terms of disease diagnosis, treatment and prevention. Nanomaterials aided drug delivery provides an advantage by enhancing aqueous solubility that leads to improved bioavailability, increased resistance time in the body, decreased side effects by targeting drugs to the specific location, reduced dose dependent toxicity and protection of drugs from early release. In this volume, the contributors have compiled reports of recent studies illustrating the promising nanomaterials that can work as drug carriers, that can navigate conventional physiological barriers. A detailed account of several types of nanomaterials including polymeric nanoparticles, liposomes, dendrimers, micelles, carbon nanomaterials, magnetic nanoparticles, solid lipid-based nanoparticles, silica nanomaterials and hydrogels for drug delivery is provided in separate chapters. The contributors also present a discussion on clinical aspects of ongoing research with insights towards future prospects of specific nanotechnologies. The book is an informative resource for scholars who seek updates in nanomedicine with reference to nanomaterials used in drug delivery systems.

Author: Surendra Nimesh; Nidhi
Publisher:
ISBN: 9781681088259
Category :
Languages : en
Pages : 315

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Book Description
The development of a vector for the delivery of therapeutic drugs in a controlled and targeted fashion is still a major challenge in the treatment of many diseases. The conventional application of drugs may lead to many limitations including poor distribution, limited effectiveness, lack of selectivity and dose dependent toxicity. An efficient drug delivery system can address these problems. Recent nanotechnology advancements in the biomedical field have the potential to meet these challenges in developing drug delivery systems. Nanomaterials are changing the biomedical platform in terms of disease diagnosis, treatment and prevention. Nanomaterials aided drug delivery provides an advantage by enhancing aqueous solubility that leads to improved bioavailability, increased resistance time in the body, decreased side effects by targeting drugs to the specific location, reduced dose dependent toxicity and protection of drugs from early release. In this two-part book, the contributors have compiled reports of recent studies illustrating the promising nanomaterials that can work as drug carriers which can navigate conventional physiological barriers. A detailed account of several types of nanomaterials including polymeric nanoparticles, liposomes, dendrimers, micelles, carbon nanomaterials, magnetic nanoparticles, solid lipid-based nanoparticles, silica nanomaterials and hydrogels for drug delivery is provided in separate chapters. The contributors also present a discussion on clinical aspects of ongoing research with insights towards future prospects of specific nanotechnologies. Part II covers the following topics: · Solid lipid nanoparticles and nanostructured lipid carriers · Silica based nanomaterials · Hydrogels · Metallic nanoparticles · Computational and experimental binding interactions of drug and β-cyclodextrin · Clinical milestones in nanotherapeutics · Drug delivery systems based on poly(lactide-co-glycolide) and its copolymers The book set is an informative resource for scholars who seek updates in nanomedicine with reference to nanomaterials used in drug delivery systems.

Author: Alexandru Mihai Grumezescu
Publisher: William Andrew
ISBN: 0128166290
Category : Science
Languages : en
Pages : 581

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Book Description
Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. - Assesses the opportunities and challenges of nanotechnology-based drug delivery systems - Explores how nanotechnology is being used to create more efficient drug delivery systems - Discusses which nanomaterials make the best drug carriers

Author: Md Sabir Alam
Publisher: CRC Press
ISBN: 1000967018
Category : Technology & Engineering
Languages : en
Pages : 416

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Book Description
Metallic Nanoparticles for Health and the Environment covers different routes of synthesis for metallic nanoparticles and their process variables. Both the functions and roles of these particles as a drug delivery system and diagnostic agent and other potential theranostic purposes against metabolic disorders, photocatalysis applications, as well as wastewater treatments, are discussed. The book compares the different properties of bulk metallic forms and their nanoparticulated forms. It discusses the mechanisms and impacts of different process variables in different synthesis routes, as well as emerging trends in clinics and so forth. Features: Covers different routes of synthesis to create metallic nanoparticles (MNPs) of different characteristics with reference to bulk forms of metals. Describes formulation parameters that have a significant effect on these MNPs including dimensions, morphology, mechanism, surface properties, and other characteristics. Discusses different roles and performances of MNPs in photothermal therapy, metabolic disorders, mechanisms in bacterial, fungal, and viral infections, and inflammatory pathways. Reviews the potential and emerging roles of different MNPs with site target delivery applications and genetic manipulation purposes. Examines the advantages and challenges of these MNPs against remediation of pollutants and toxicants, owing to their superior surface catalytic activities. This book is aimed at researchers and professionals in nanomaterials, pharmaceuticals, and drug delivery.

Author:
Publisher: Academic Press
ISBN: 0128141700
Category : Medical
Languages : en
Pages : 224

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Book Description
Advances in Cancer Research, Volume 139, provides invaluable information on the exciting and fast-moving field of cancer research. Original reviews are presented on a variety of topics relating to the rapidly developing intersection between nanotechnology and cancer research, with unique sections in the new release focusing on Exosomes as a theranostic for lung cancer, Nanotechnology and cancer immunotherapy, Ultrasound imaging agents and delivery systems, Dendronized systems for the delivery of chemotherapeutics, Thermosensitive liposomes for image-guided drug delivery, Supramolecular Chemistry in Tumor Analysis and Drug Delivery, Gold nanoparticles for delivery of cancer therapeutics, and Single cell barcode microchip for cancer research and therapy. - Provides the latest information on cancer research - Offers outstanding and original reviews on a range of cancer research topics - Serves as an indispensable reference for researchers and students alike

Author: Ecaterina Andronescu
Publisher: Elsevier
ISBN: 0323461492
Category : Technology & Engineering
Languages : en
Pages : 1026

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Book Description
Nanostructures for Drug Delivery extensively covers the various nanostructured products that have been tested as carriers in target drug delivery systems. In addition, the book analyses the advantages of, and issues related to, using nanostructured materials in drug delivery systems, also detailing various nanocarrier preparation techniques. As delivering the drug to the target site is a major problem in providing effective treatment for many diseases, this book covers the latest advancements in numerous nanotechnological products that are being used in disease detection, controlled drug delivery, as biosensors, and in tissue engineering that have been developed for more efficient patient healthcare. Due to the versatility of nanostructured materials, it is now possible to deliver a drug at its target site in a more accurate and efficient way. This volume is an up-to-date, state-of-the-art work that highlights the principal mechanistic aspects related to the delivery of active nanoscale therapeutic agents (natural or synthetic) and their release profile in different environmental media. It highlights nanoscale encapsulation strategies and discusses both organic and inorganic nanomaterials as carriers and delivery platforms. - Demonstrates how nanostructures are successfully employed in drug delivery stems and as drug delivery agents, allowing biomaterials scientists and biochemists to create more effective drug delivery systems - Offers an overview of recent research into the use of nanostructures in drug delivery techniques in a cogent, synthesized way, allowing readers to quickly familiarize themselves with this area - Includes examples of how the application of nanostructures have improved the efficiency of drug delivery systems, showing medical scientists how they are beneficial

Author: Yasemin Gürsoy Özdemir
Publisher: Academic Press
ISBN: 9780128037966
Category : Medical
Languages : en
Pages : 0

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Book Description
Nanotechnology Methods for Neurological Diseases and Brain Tumors: Drug Delivery across the Blood-Brain Barrier compiles the latest (and future potential) treatment strategies for brain tumors and neurological diseases, in particular Alzheimer's, Parkinson's and stroke, those that bypass the blood/brain barrier. The current understanding of brain drug delivery and access is discussed in Chapter One, with the next section focusing on the implementation of the nose-to-brain intranasal route in brain-targeted drug delivery. In addition, nanotechnology-based brain drug delivery is covered in Chapter Three. This avenue offers impressive improvement in the treatment of neurological diseases and brain tumors by using bio-engineered systems that interact with biological systems at a molecular level. In Chapter Four, emphasis is placed on the need for brain-targeted experimental models that mimic disease conditions. Final chapters discuss the very latest advances in targeted treatment strategies for neurological diseases and brain tumors.

Author: Mohamed Fawzy Ramadan
Publisher: CRC Press
ISBN: 1000953238
Category : Technology & Engineering
Languages : en
Pages : 381

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Book Description
Ghee (clarified milk fat) is a dairy product composed mainly of milk fat and minor components, such as vitamins, minerals, and enzymes; and butter oil has a bland flavor, whereas ghee has a pleasing flavor. In 18 chapters, Ghee: Chemistry, Technology, and Health Aspects covers topics focusing on ghee chemistry and physicochemical properties, and ghee processing and applications, as well as ghee biosafety and health effects. Features: Explores the chemistry of ghee from different dairy sources Discusses ghee functional constituents and their health-enhancing potential Written by industry experts and international scientists Addresses ghee-growing applications in clinical nutrition, functional foods, pharmaceuticals, nutraceuticals, and cosmetics Authored by a team of experts, this book brings a diversity of lipid science developments to chemists, nutritionists, and researchers in the fields of food science, nutrition, food chemistry and technology, cosmetics, and nutraceuticals. This book is an essential textbook for healthy food developers as well as the research and development (R&D) researchers using milk fats. Meanwhile, it is a valuable reference work for edible fat and oil companies reformulating their products or developing new healthy products.

Author: Amit Singh
Publisher: Royal Society of Chemistry
ISBN: 1788014669
Category : Technology & Engineering
Languages : en
Pages : 376

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Book Description
The increased understanding of molecular aspects associated with chronic diseases, such as cancer and the role of tumor microenvironment, has led to the identification of endogenous and exogenous stimuli that can be exploited to devise “stimuli-responsive” materials for site-specific drug delivery applications. This book provides a comprehensive account on the design, materials chemistry, and application aspects behind these novel stimuli-responsive materials. Setting the scene, the editors open with a chapter addressing the need for smart materials in delivery applications for therapy, imaging and disease diagnosis. The following chapter describes the key physical and chemical aspects of smart materials, from lipids to polymers to hybrid materials, providing the reader with a springboard to delve into the more application oriented chapters that follow. With in-depth coverage of key drug delivery systems such as pH-responsive, temperature responsive, enzyme-responsive and light responsive systems, this book provides a rigorous foundation to the field. A perfect resource for graduate students and newcomers, the closing chapter on regulatory and commercialization challenges also makes the book ideal for those wanting to take the next step towards clinical translation.

Author: Adnan Nasir
Publisher: Springer Science & Business Media
ISBN: 1461450349
Category : Medical
Languages : en
Pages : 299

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Book Description
Nanotechnology in Dermatology is the first book of its kind to address all of the important and rapidly growing aspects of nanotechnology as it relates to dermatology. In the last few years there has been an explosion in research and development for products and devices related to nanotechnology, including numerous applications for consumers, physicians, patients, and industry. Applications are underway in medicine and dermatology for the early detection, diagnosis, and targeted therapy of disease, and nanodesigned materials and devices are expected to be faster, smaller, more powerful, more efficient, and more versatile than their traditional counterparts. Written by experts working in this exciting field, Nanotechnology in Dermatology specifically addresses nanotechnology in consumer skin care products, in the diagnosis of skin disease, in the treatment of skin disease, and the overall safety of nanotechnology. The book also discusses future trends of this ever-growing and changing field, providing dermatologists, pharmaceutical companies, and consumer cosmetics companies with a clear understanding of the advantages and challenges of nanotechnology today.