Myocardial Protection and the KATP Channel PDF Download

Author: Tomas A. Salerno
Publisher: John Wiley & Sons
ISBN: 1405178434
Category : Medical
Languages : en
Pages : 344

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Book Description
Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.

Author: Derek Yellon
Publisher: Springer Science & Business Media
ISBN: 9780792337911
Category : Medical
Languages : en
Pages : 232

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Book Description
The ATP-sensitive potassium channel (KATP) was discovered in 1983. Since then, an enormous amount of research has been undertaken to characterize it in detail. This volume consolidates both the current knowledge and most recent advances on the subject, and its relationship to myocardial protection. To this end, the editors have assembled investigators at the forefront of ongoing basic and clinical research to provide scholarly and candid comments concerning each of the pertinent issues, including: a comprehensive review of the biology of the channel with respect to the structure-activity relationship as well as overall chemistry of the channel; the role of opening this channel and its effect on smooth muscle (covering both the effects on myocardial stunning and its ability to protect against myocardial infarction); the relationship of KATP channel opening and the protection to the myocardium afforded by the phenomenon of ischemic preconditioning; the relationship between the KATP channel and electrophysiological consequences with specific reference to arrhythmogenicity; and the clinical implications of the use of agents that mimic the opening of this channel, with reference to its protective nature and its use in the treatment of angina. Audience: Clinicians and basic scientists who have a direct interest in the KATP channel as well as those groups who are interested in the entire concept of myocardial protection and its relationship to academic and clinical medicine.

Author: Ihor Gussak
Publisher: Springer Science & Business Media
ISBN: 1447148819
Category : Medical
Languages : en
Pages : 661

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Book Description
Electrical Disease of the Heart, 2nd Edition, volume 1, provides a valuable insight to the latest developments in the field of cardiac electrophysiology and clinical electrocardiology. Each chapter includes up-to-date results of studies aimed at providing an understanding of the electrical function of the heart in health and disease, established and evidence-based knowledge of clinical outcomes, areas of controversy, and future trends. This book is highly relevant to a broad audience, ranging from medical and graduate students, to clinicians and scientists.

Author: Anwar-Saad A. Abd-Elfattah
Publisher: Springer Science & Business Media
ISBN: 1461304555
Category : Medical
Languages : en
Pages : 565

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Book Description
A critical review of the most up-to-date research on purines and myocardial protection. The role of purines in reversible `myocardial stunning' and irreversible (myocardial infarction) ischemic injury, ventricular arrhythmias, and ischemic preconditioning is discussed in detail, by experts. All reviews address recent and rather controversial issues on purines and myocardial protection. Mechanisms of cardioprotection of exogenous versus endogenous purines are discussed in detail. The contribution of internationally recognized experts in the field of purines and cardiovascular physiology and in myocardial protection makes this a unique and interesting book for clinicians, basic scientists and students.

Author: Michitoshi Inoue
Publisher: Springer Science & Business Media
ISBN: 4431683674
Category : Medical
Languages : en
Pages : 330

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Book Description
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.

Author: Joyce LeFever Kee
Publisher: Elsevier Health Sciences
ISBN: 0323674224
Category : Medical
Languages : en
Pages : 4094

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Book Description
- NEW! Updated information on Antidiabetic Agents (orals and injectables) has been added throughout the text where appropriate. - NEW! Updated content on Anticoagulant Agents is housed in an all-new chapter. - NEW! Colorized abbreviations for the four methods of calculation (BF, RP, FE, and DA) appear in the Example Problems sections. - NEW! Updated content and patient safety guidelines throughout the text reflects the latest practices and procedures. - NEW! Updated practice problems across the text incorporate the latest drugs and dosages.

Author: Jonathan H. Mackay
Publisher: Cambridge University Press
ISBN: 9780521196857
Category : Medical
Languages : en
Pages : 0

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Book Description
Since the publication of the first edition of Core Topics in Cardiac Anaesthesia, the clinical landscape has undergone significant change. Recent developments include the increased use of electrophysiology, the resurgence of primary percutaneous intervention in acute coronary syndromes, the use of percutaneous devices in patients previously considered inoperable, and the withdrawal of aprotinin. Against this landscape, this invaluable resource has been fully updated. New chapters are dedicated to right heart valves, pulmonary vascular disease, cardiac tumours and cardiac trauma. All other chapters have been updated according to the latest international guidelines. Written and edited by an international author team with a wealth of expertise in all aspects of the perioperative care of cardiac patients, topics are presented in an easy to digest and a readily accessible manner. Core Topics in Cardiac Anaesthesia, Second Edition is essential reading for residents and fellows in anaesthesia and cardiac surgery and clinical perfusionists.

Author: Nicholas Sperelakis
Publisher: Elsevier
ISBN: 0080574556
Category : Science
Languages : en
Pages : 1262

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Book Description
This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Third Edition contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, the regulation of cell division, and programmed cell death. - Completely revised and updated - includes 8 new chapters on such topics as membrane structure, intracellular chloride regulation, transport, sensory receptors, pressure, and olfactory/taste receptors - Includes broad coverage of both animal and plant cells - Appendixes review basics of the propagation of action potentials, electricity, and cable properties - Authored by leading experts in the field - Clear, concise, comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics

Author: Ronald D. Miller
Publisher: Elsevier Health Sciences
ISBN: 0323280110
Category : Medical
Languages : en
Pages : 4094

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Book Description
From fundamental principles to advanced subspecialty procedures, Miller’s Anesthesia covers the full scope of contemporary anesthesia practice. This go-to medical reference book offers masterful guidance on the technical, scientific, and clinical challenges you face each day, in addition to providing the most up-to-date information available for effective board preparation. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Address the unique needs of pediatric patients with guidance from an entire section on pediatric anesthesia. View more than 1,500 full-color illustrations for enhanced visual clarity. Access step-by-step instructions for patient management, as well as an in-depth analysis of ancillary responsibilities and problems. Quickly reference important concepts with ‘Key Points’ boxes integrated into every chapter. Stay current on today's most recent anesthetic drugs and guidelines/protocols for anesthetic practice and patient safety, and access expanded coverage on new techniques such as TEE and other monitoring procedures. Take advantage of the unique, international perspectives of prominent anesthesiologists from all over the world, including the UK, Australia, India, Brazil, and Germany. Remain at the forefront of new developments in anesthesia with coverage of hot topics including Non-OR Anesthesia; Role of the Anesthesiologist in Disasters; Sleep Medicine in Anesthesia; Perioperative and Anesthesia-related Neurotoxicity; Anesthetic Implications of Complementary and Alternative Medicine; and Robotics. Study brand-new chapters on Perioperative Fluid Management; Extracorporeal Support Therapies; Anesthesia for Organ Donation/Procurement; and Malignant Hyperthermia and other Genetic Disorders.

Author: Glenn P. Gravlee
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781768153
Category : Medical
Languages : en
Pages : 814

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Book Description
Established as the standard reference on cardiopulmonary bypass, Dr. Gravlee's text is now in its Third Edition. This comprehensive, multidisciplinary text covers all aspects of cardiopulmonary bypass including sections on equipment, physiology and pathology, hematologic aspects, and clinical applications. This edition features a new section on cardiopulmonary bypass in neonates, infants, and children and a new chapter on circulatory support for minimally invasive cardiac surgery. Other highlights include state-of-the-art information on low-volume circuits and other new equipment and discussions of outcomes data for on-pump and off-pump surgeries.