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Author: Friedhelm Beyersdorf Publisher: CRC Press ISBN: Category : Medical Languages : en Pages : 250
Book Description
Cardiac surgery is associated with ischemia and reperfusion injury for most of the operations performed. During the last decades, major improvements have been done in reducing both ischemic and reperfusion injury and therefore improving the quality of the operation. This book summarizes the newest developments in this field. In addition, specific comments are made concerning the surgical application of the fields in all kinds of operation, including routine cases as well as complex procedures. The reader will gain a detailed insight regarding how to protect patients best during routine cardiac procedures (coronary artery revascularization and valve replacement) as well as prolonged, technically demanding operations
Author: Friedhelm Beyersdorf Publisher: CRC Press ISBN: Category : Medical Languages : en Pages : 250
Book Description
Cardiac surgery is associated with ischemia and reperfusion injury for most of the operations performed. During the last decades, major improvements have been done in reducing both ischemic and reperfusion injury and therefore improving the quality of the operation. This book summarizes the newest developments in this field. In addition, specific comments are made concerning the surgical application of the fields in all kinds of operation, including routine cases as well as complex procedures. The reader will gain a detailed insight regarding how to protect patients best during routine cardiac procedures (coronary artery revascularization and valve replacement) as well as prolonged, technically demanding operations
Author: Hans Michael Piper Publisher: Springer Science & Business Media ISBN: 9401117136 Category : Medical Languages : en Pages : 457
Book Description
In open heart surgery, protection of the myocardium against injury by ischemia-reperfusion is an issue of utmost clinical interest. The knowledge on the causal mechanisms of myocardial injury in ischemia-reperfusion has greatly progressed in recent years, both to clinical and experimental research. This book provides a critical and comprehensive overview on the current discussion of myocardial protection in cardiac experimental research and surgery. Leading groups from Europe, the U.S. and Japan have contributed reviews of their special fields. On the basic science side, major topics discussed are the mechanisms of stunning and lethal reperfusion injury, the role of the endothelium and leukocyte activation in postischemic myocardial dysfunction, and the differences between the adult and neonatal myocardium. On the clinical side, the major concepts and procedures for cardioplegic myocardial protection, their rationales, application and respective merits are discussed. In a third part of the book, possible approaches for the monitoring of myocardial injury during ischemia and reperfusion are evaluated, with particular attention to their intraoperative use. This book brings together the scientific discussions on ischemia-reperfusion in experimental cardiology and cardiac surgery, a task needed for a long time. It is of general interest for clinicians as well as research workers and students in the cardiac field.
Author: Tomas A. Salerno Publisher: John Wiley & Sons ISBN: 1405178434 Category : Medical Languages : en Pages : 344
Book Description
Myocardial protection is regarded as one of the most important, yet also most controversial aspects of cardiac surgery. There has been considerable improvement in myocardial protection strategies over recent years, utilising a variety of new approaches to treat cardiac diseases, and this text is intended to embrace the state of the art in this field. The book summarises the state of knowledge on all aspects of myocardial protection, including the latest in the treatment of cardiac diseases, robotics, pediatric surgery and the treatment of cardiac failure. Robotic surgery, valvular surgery, pediatric surgery and coronary surgery are all covered by renowned experts, producing a comprehensive, forward-looking view of the field of myocardial protection. This book should function to update physicians and surgeons interested in the field of cardiac surgery on the current state of knowledge on myocardial protection.
Author: Tommi Vähäsilta Publisher: ISBN: 9789512929337 Category : Languages : en Pages : 88
Book Description
Tiivistelmä: Tutkimus ohjelmoidun solukuoleman ja sydämen suojauksen vaikutuksista avosydänleikkauksen aikaisen sydänlihasvaurion syntyyn koe-eläinmallissa.
Author: Juan Carlos Kaski Publisher: Springer Science & Business Media ISBN: 1849960194 Category : Medical Languages : en Pages : 311
Book Description
Much has been written about reperfusion injury in the past decade but unfortunately the information has been generally presented in the form of original specialist papers and little if any integral publication exists on the topic, summarising and analysing the clinical impact of the condition and its management. The pathophysiology and molecular mechanisms of reperfusion injury are complex and, regarding diagnosis, individual diagnostic techniques have been proposed but without a proper assessment of the relative values of these methods. A publication dealing with integral diagnostic strategies would be welcome by the managing physician. Management of the condition is also problematic, as strategies that appear to work in the experimental models do not translate into beneficial interventions in patients. There is a need for these issues to be addressed and discussed in a monographic fashion. Management of Myocardial Reperfusion Injury will tackle these issues in a modern and systematic way and the information will be delivered in a fashion that will be appealing to the reader.
Author: Dennis V. P. Cokkinos Publisher: Springer Science & Business Media ISBN: 0387286586 Category : Medical Languages : en Pages : 212
Book Description
Effective new treatments of heart disease are based on a refined understanding of cellular function and the heart's response to environmental stresses. Not surprisingly therefore, the field of experimental cardiology has experienced a phase of rapid expo nential growth during the last decade. The acquisition of new knowledge has been so fast that textbooks of cardiology or textbooks of cardiovascular physiology are often hard-pressed to keep up with the most important conceptual advances. Witness the explosive increase in knowledge about signaling pathways of cardiac growth, transcrip tional regulation of cardiac metabolism, hormonal signaling, and the complex responses of the heart to ischemia, reperfusion, or ischemic preconditioning. This book is meant to bridge the gap between original literature and textbook reviews. It brings together inves tigators of various backgrounds who share their expertise in the biology of myocardial ischemia. Each chapter is a self-contained mini-review, but it will soon become apparent to the reader that there is also a common thread: Molecular and cellular cardiology has never been more exciting than now, but ever more exciting times are yet to come. The Editors ACKNOWLEDGEMENTS - Publication of this book was generously supported by Sanofi-Aventis Hellas. - Eikon creative team provided the technical assistance in preparing the manuscripts. - We thank Dr. Bernard Swynghedauw for all his scientific support.
Author: Seibu Mochizuki Publisher: Springer ISBN: 0585398445 Category : Medical Languages : en Pages : 601
Book Description
Over the past three decades, impressive progress in the field of pathogenesis, prevention and therapy of ischemic heart disease has resulted in a marked decline in mortality in the Western World. However, the incidence of this devastating disease is on the rise in developing countries. The Ischemic Heart is based upon a recent symposium in Tokyo on the subject. This volume is organized into two sections: (i) Pathophysiologic Mechanisms of Ischemia-Reperfusion Injury and (ii) Preconditioning and Protection of Ischemia-Reperfusion Injury, and contains up-to-date information concerning the current concepts of ischemia-reperfusion injury, the sequence of events resulting in the loss of contractile dysfunction, and mechanisms of cardioprotection by several drugs as well as the role of ischemic preconditioning in attenuating problems associated with ischemia-reperfusion injury.
Author: Robert Fitridge Publisher: University of Adelaide Press ISBN: 1922064009 Category : Medical Languages : en Pages : 589
Book Description
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Author: Paul A. Iaizzo Publisher: Springer ISBN: 331919464X Category : Medical Languages : en Pages : 817
Book Description
This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.
Author: Friedhelm Beyersdorf
Author: Friedhelm Beyersdorf
Author: Hans Michael Piper
Author: Tomas A. Salerno
Author: Tommi Vähäsilta
Author: Juan Carlos Kaski
Author: Antti Vento
Author: Dennis V. P. Cokkinos
Author: Seibu Mochizuki
Author: Robert Fitridge
Author: Paul A. Iaizzo