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Author: Jean-Pierre Aubin Publisher: Springer Science & Business Media ISBN: 9780817639358 Category : Mathematics Languages : en Pages : 472
Book Description
The analysis, processing, evolution, optimization and/or regulation, and control of shapes and images appear naturally in engineering (shape optimization, image processing, visual control), numerical analysis (interval analysis), physics (front propagation), biological morphogenesis, population dynamics (migrations), and dynamic economic theory. These problems are currently studied with tools forged out of differential geometry and functional analysis, thus requiring shapes and images to be smooth. However, shapes and images are basically sets, most often not smooth. J.-P. Aubin thus constructs another vision, where shapes and images are just any compact set. Hence their evolution -- which requires a kind of differential calculus -- must be studied in the metric space of compact subsets. Despite the loss of linearity, one can transfer most of the basic results of differential calculus and differential equations in vector spaces to mutational calculus and mutational equations in any mutational space, including naturally the space of nonempty compact subsets. "Mutational and Morphological Analysis" offers a structure that embraces and integrates the various approaches, including shape optimization and mathematical morphology. Scientists and graduate students will find here other powerful mathematical tools for studying problems dealing with shapes and images arising in so many fields.
Author: Jean-Pierre Aubin Publisher: Springer Science & Business Media ISBN: 9780817639358 Category : Mathematics Languages : en Pages : 472
Book Description
The analysis, processing, evolution, optimization and/or regulation, and control of shapes and images appear naturally in engineering (shape optimization, image processing, visual control), numerical analysis (interval analysis), physics (front propagation), biological morphogenesis, population dynamics (migrations), and dynamic economic theory. These problems are currently studied with tools forged out of differential geometry and functional analysis, thus requiring shapes and images to be smooth. However, shapes and images are basically sets, most often not smooth. J.-P. Aubin thus constructs another vision, where shapes and images are just any compact set. Hence their evolution -- which requires a kind of differential calculus -- must be studied in the metric space of compact subsets. Despite the loss of linearity, one can transfer most of the basic results of differential calculus and differential equations in vector spaces to mutational calculus and mutational equations in any mutational space, including naturally the space of nonempty compact subsets. "Mutational and Morphological Analysis" offers a structure that embraces and integrates the various approaches, including shape optimization and mathematical morphology. Scientists and graduate students will find here other powerful mathematical tools for studying problems dealing with shapes and images arising in so many fields.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309047986 Category : Medical Languages : en Pages : 353
Book Description
Raising hopes for disease treatment and prevention, but also the specter of discrimination and "designer genes," genetic testing is potentially one of the most socially explosive developments of our time. This book presents a current assessment of this rapidly evolving field, offering principles for actions and research and recommendations on key issues in genetic testing and screening. Advantages of early genetic knowledge are balanced with issues associated with such knowledge: availability of treatment, privacy and discrimination, personal decision-making, public health objectives, cost, and more. Among the important issues covered: Quality control in genetic testing. Appropriate roles for public agencies, private health practitioners, and laboratories. Value-neutral education and counseling for persons considering testing. Use of test results in insurance, employment, and other settings.
Author: Jean-Pierre Aubin Publisher: Springer Science & Business Media ISBN: 0817648488 Category : Science Languages : en Pages : 474
Book Description
"An elegantly written, introductory overview of the field, with a near perfect choice of what to include and what not, enlivened in places by historical tidbits and made eminently readable throughout by crisp language. It has succeeded in doing the near-impossible—it has made a subject which is generally inhospitable to nonspecialists because of its ‘family jargon’ appear nonintimidating even to a beginning graduate student." —The Journal of the Indian Institute of Science "The book under review gives a comprehensive treatment of basically everything in mathematics that can be named multivalued/set-valued analysis. ...The book is highly recommended for mathematicians and graduate students who will find here a very comprehensive treatment of set-valued analysis." —Mathematical Reviews "This book provides a thorough introduction to multivalued or set-valued analysis... The style is lively and vigorous, the relevant historical comments and suggestive overviews increase the interest for this work...Graduate students and mathematicians of every persuasion will welcome this unparalleled guide to set-valued analysis." —Zentralblatt Math
Author: Masatoshi Nei Publisher: OUP Oxford ISBN: 0199661731 Category : Science Languages : en Pages : 261
Book Description
The purpose of this book is to present a new theory of mutation-driven evolution, which is based on recent advances in genomics and evolutionary developmental biology. This theory asserts that the driving force of evolution is mutation and natural selection is of secondary importance.
Author: John P. Bilezikian Publisher: Academic Press ISBN: 0080568750 Category : Medical Languages : en Pages : 2074
Book Description
Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition
Author: Eliza B. Geer Publisher: Springer ISBN: 3319459503 Category : Medical Languages : en Pages : 323
Book Description
Cushing ́s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.
Author: Joanna Jankowicz-Cieslak Publisher: Springer ISBN: 3319450212 Category : Science Languages : en Pages : 343
Book Description
This book is open access under a CC BY-NC 2.5 license. This book offers 19 detailed protocols on the use of induced mutations in crop breeding and functional genomics studies, which cover topics including chemical and physical mutagenesis, phenotypic screening methods, traditional TILLING and TILLING by sequencing, doubled haploidy, targeted genome editing, and low-cost methods for the molecular characterization of mutant plants that are suitable for laboratories in developing countries. The collection of protocols equips users with the techniques they need in order to start a program on mutation breeding or functional genomics using both forward and reverse-genetic approaches. Methods are provided for seed and vegetatively propagated crops (e.g. banana, barley, cassava, jatropha, rice) and can be adapted for use in other species.
Author: Robin Cook Publisher: Penguin ISBN: 9780425119655 Category : Fiction Languages : en Pages : 356
Book Description
In this masterpiece of techno-medical suspense from the “master of the medical thriller” (The New York Times), Robin Cook tells the explosive tale of a brilliant doctor who sought to create the son of his dreams—and invented a living nightmare... When OB/GYN and biomolecular researcher Dr. Victor Frank learns of his wife’s infertility, he initiates a bold—and dangerous—experiment. Unbeknownst to everyone, including her, Dr. Frank has adapted the methods of animal husbandry and molecular genetics to human reproduction. Fusing his wife’s eggs and his own sperm, he sets in motion the production of a superior being, his child. The result of this experiment, a son, VJ, is born to a surrogate mother and legally adopted by the Franks. To their delight, their son is physically perfect, and by the age of three, displays the complex problem-solving abilities of a prodigy. Then, without warning, VJ’s intelligence level plunges to a point appropriate to his age, but stabilizes. For the moment, Dr. Frank can breathe a sigh of relief: even if VJ is no longer the genius he was, at least he will be normal. But that relief is tragically short-lived, for all too soon VJ begins to change again. And this time, there is no cause for comfort—only terror.
Author: Jean-Pierre Aubin
Author: Jean-Pierre Aubin
Author: Institute of Medicine
Author: Jean-Pierre Aubin
Author: 
Author: Masatoshi Nei
Author: John P. Bilezikian
Author: Eliza B. Geer
Author: Joanna Jankowicz-Cieslak
Author: Robin Cook
Author: Jonathan Howard Blum