Multiphase Solid-liquid-liquid Mixing in Stirred Tanks PDF Download

Author: George R. DeRitter
Publisher:
ISBN:
Category : Dispersion
Languages : en
Pages : 208

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Book Description

Author: Jessyca Susanto
Publisher:
ISBN:
Category : Impellers
Languages : en
Pages : 334

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Book Description

Author: Reiji Reiji Mezaki
Publisher: Elsevier
ISBN: 0080531008
Category : Technology & Engineering
Languages : en
Pages : 781

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Book Description
This book is a compilation of the engineering data on mixing, which have appeared in the major technical journals of chemical engineering and bioengineering since 1975. That year marked the beginning of a period of rapid advancement in the science and technology of mixing, with rather reliable results for both theoretical and experimental studies. In addition, some important earlier articles which have been, and still are being referred to, are included.Designs of both agitators and tanks still depend primarily on art and experience. In light of this it was felt that the data on mixing should be compiled and presented in a systematic manner to assist in design and analysis of agitated tanks, and to provide easier access to mixing data for various engineering activities. Although computer-aided searches of pertinent data bases can be of assistance to chemical engineers and bioengineers in their studies, they are sometimes time-consuming and often costly. Furthermore inadequate selection of key words can jeopardize the searches. This book offers an alternative method of surveying mixing data which interests readers. The first chapter presents a variety of results for the experimental measurements of flow patterns in stirred tanks. Most of the measurements were made by using modern Laser-Doppler techniques. This chapter is useful for the prediction of flow patterns in tanks with many different geometries, various types of agitators, and fluids of diverse physical and rheological properties, plus valuable data for the validation of results obtained by CFD simulations. Chapters 2 through 5 deal with data for traditional chemical engineering subjects and Chapter 6 summarizes a number of scale-up relations developed over the years for various systems. These include liquid, solid-liquid, liquid-liquid, gas-liquid, and solid-liquid-gas systems. Chapter 7 provides data related to multiphase processes, and most importantly, drop size and drop-size distributions and bubble-size distributions. These two subjects have not been treated systematically either in text books or in handbooks on stirred-tank mixing, although the results of both experimental and theoretical investigations have been reported on many occasions. Finally gas-inducing mechanically agitated systems are dealt with. The applications of this type of agitation system will become increasingly attractive from the standpoint of rationalization of stirred-tank operations as well as environmental protection.

Author: Ochieng Aoyi
Publisher: LAP Lambert Academic Publishing
ISBN: 9783838312903
Category :
Languages : en
Pages : 196

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Book Description
Hydrodynamics in a mixing tanks results from the interaction between the tank geometry and the performance characteristics of the tank internals such as impeller and draft tube. In this book, the standard stirred tank configurations are investigated using both laser Doppler velocimetry (LDV) and computational fluid dynamics (CFD) techniques. The work first focuses on establishing the velocity field in a liquid-only system and then progresses to a solid-liquid system. In the liquid only system, it is shown that a draft tube can be used in a tank stirred by the Rushton turbine, and this improves mixing efficiency and reduces power consumption. For the solid-liquid systems, CFD simulation techniques are developed to determine multiphase mixing features such as cloud height and off-bottom suspension. Poly-disperse multiphase simulation results show the effect of particle size distribution and that of the drag model. The results provide useful information for process optimization and scale up.

Author: H. Benkreira
Publisher:
ISBN: 9780852954256
Category : Science
Languages : en
Pages : 464

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Book Description
This work deals with all aspects of mixing solids, liquids and gases in single and multi-phase flow and therefore reflects the modern use of non-intrusive methods and simulations by computational fluid dynamics.

Author: Mary T. am Ende
Publisher: John Wiley & Sons
ISBN: 111928550X
Category : Technology & Engineering
Languages : en
Pages : 1435

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Book Description
A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.

Author: Jaromír J. Ulbrecht
Publisher: Taylor & Francis
ISBN: 9782881241123
Category : Science
Languages : en
Pages : 360

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Book Description
First published in 1985. Routledge is an imprint of Taylor & Francis, an informa company.

Author: F. A. Holland
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 338

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Book Description

Author: Edward L. Paul
Publisher: John Wiley & Sons
ISBN: 9780471269199
Category : Reference
Languages : en
Pages : 1458

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Book Description
Dieses Handbuch beantwortet Ihnen alle Fragen zur Mischtechnik in der Industrie. Grundlagen, dargeboten in klarem, anschaulichem Stil, sind verknüpft mit Tipps von Experten für die Praxis und vielen Anwendungsbeispielen. Mitgeliefert wird eine CD-ROM mit Videosequenzen, die verschiedene Mischer in Aktion zeigen.

Author: David J. am Ende
Publisher: John Wiley & Sons
ISBN: 1119285860
Category : Technology & Engineering
Languages : en
Pages : 1172

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Book Description
A guide to the development and manufacturing of pharmaceutical products written for professionals in the industry, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry is a practical book that highlights chemistry and chemical engineering. The book’s regulatory quality strategies target the development and manufacturing of pharmaceutically active ingredients of pharmaceutical products. The expanded second edition contains revised content with many new case studies and additional example calculations that are of interest to chemical engineers. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The active pharmaceutical ingredients book puts the focus on the chemistry, chemical engineering, and unit operations specific to development and manufacturing of the active ingredients of the pharmaceutical product. The drug substance operations section includes information on chemical reactions, mixing, distillations, extractions, crystallizations, filtration, drying, and wet and dry milling. In addition, the book includes many applications of process modeling and modern software tools that are geared toward batch-scale and continuous drug substance pharmaceutical operations. This updated second edition: Contains 30new chapters or revised chapters specific to API, covering topics including: manufacturing quality by design, computational approaches, continuous manufacturing, crystallization and final form, process safety Expanded topics of scale-up, continuous processing, applications of thermodynamics and thermodynamic modeling, filtration and drying Presents updated and expanded example calculations Includes contributions from noted experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduate students, and professionals in the field of pharmaceutical sciences and manufacturing, the second edition of Chemical Engineering in the Pharmaceutical Industryf ocuses on the development and chemical engineering as well as operations specific to the design, formulation, and manufacture of drug substance and products.