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Author: Harold Morris Publisher: Springer Science & Business Media ISBN: 1461588529 Category : Medical Languages : en Pages : 773
Book Description
In 1960, Dr. Van R. Potter and Dr. Henry Pitot (at McCardle Laboratory in Madison, Wisconsin), Dr. Tetsuo Ono (then at McCardle Laboratory and now at the Japanese Foundation for Cancer Research in Tokyo, Japan) and Dr. Harold P. Morris (then at the National Cancer Institute and now at Howard University, Washington, D. C. ) decided that an experimental cancer model would be an invaluable tool to examine neoplastic changes in cells. Since they were study ing the various highly specific metabolic processes which are unique to liver tissues, they determined that a transplantable liver cancer model would be the ideal system to work with. This system would provide for comparison of normal liver tissue of the non-tumor bear ing animal, the tumor bearing animal's (host) liver and the liver cancer. Dr. Morris undertook a series of rat studies employing several chemicals known to cause liver cancer. Soon the first Morris hepatomas (#3683, 3924A, 5123) were being studied by several labs. During the next 18 years, Dr. Morris developed and transplanted numerous strains of hepatomas of which no two were identical. These tumors ranged from the very slowly-growing, highly differentiated cancer tissues, e. g. , 96l8A which is a diploid tumor containing gly cogen and a "nearly normal" complement of enzymes, to a large group of rapidly-growing, poorly differentiated cancer tissues, e. g.
Author: Harold Morris Publisher: Springer Science & Business Media ISBN: 1461588529 Category : Medical Languages : en Pages : 773
Book Description
In 1960, Dr. Van R. Potter and Dr. Henry Pitot (at McCardle Laboratory in Madison, Wisconsin), Dr. Tetsuo Ono (then at McCardle Laboratory and now at the Japanese Foundation for Cancer Research in Tokyo, Japan) and Dr. Harold P. Morris (then at the National Cancer Institute and now at Howard University, Washington, D. C. ) decided that an experimental cancer model would be an invaluable tool to examine neoplastic changes in cells. Since they were study ing the various highly specific metabolic processes which are unique to liver tissues, they determined that a transplantable liver cancer model would be the ideal system to work with. This system would provide for comparison of normal liver tissue of the non-tumor bear ing animal, the tumor bearing animal's (host) liver and the liver cancer. Dr. Morris undertook a series of rat studies employing several chemicals known to cause liver cancer. Soon the first Morris hepatomas (#3683, 3924A, 5123) were being studied by several labs. During the next 18 years, Dr. Morris developed and transplanted numerous strains of hepatomas of which no two were identical. These tumors ranged from the very slowly-growing, highly differentiated cancer tissues, e. g. , 96l8A which is a diploid tumor containing gly cogen and a "nearly normal" complement of enzymes, to a large group of rapidly-growing, poorly differentiated cancer tissues, e. g.
Author: Roeland van Wijk Publisher: Meluna / Boekenservice.nl ISBN: 9081884328 Category : Medical Languages : en Pages : 310
Book Description
The production of biological light (ultra-weak photon emission or biophotons) within many types of cells and tissues is characteristic of an alive organism. You will begin a journey of discovery about biophotons in relationship to biological matter and about how such biophotons can be detected utilizing specialized very photon-sensitive technologies. In this book, Roeland Van Wijk provides a unified synthesis that facilitates easy entry into an exciting sub-field of biology. Light in Shaping Life encompasses the history of biophoton research, insight into how biophotons are generated, and into their involvement with life. Also included, is an overview of the potential benefits of such research to a better understanding of health and medicine. There is sequel to Light in Shaping Life available: Biophoton Technology in Energy and Vitality Diagnostics A Multi-disciplinary, Systems biology, and Biotechnology Appraoch Roeland van Wijk, Yu Yan and Eduard van Wijk Meluna, 2017 ISBN 9789081884341
Author: I. Bekhor Isaac Publisher: CRC Press ISBN: 1351092960 Category : Medical Languages : en Pages : 267
Book Description
The purpose of this text is to encourage research on nonhistones and to stimulate the imagination of other investigators whose future efforts might result in new discoveries as to the significance of these proteins.
Author: M. A. Hayat Publisher: Academic Press ISBN: 0124055346 Category : Medical Languages : en Pages : 432
Book Description
Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst encouraging researchers to explore their potentially important connections. Volume 3 explores the role of autophagy in specific diseases and developments, including: Crohn’s Disease, Gaucher Disease, Huntington’s Disease, HCV infection, osteoarthritis, and liver injury. A full section is devoted to in-depth exploration of autophagy in tumor development and cancer. Finally, the work explores the relationship between autophagy and apoptosis, with attention to the ways in which autophagy regulates apoptosis, and the ways in which autophagy has been explored in Lepidoptera, elucidating the use of larval midgut as a model for such exploration. From these well-developed foundations, researchers, translational scientists, and practitioners may work to better implement more effective therapies against some of the most devastating human diseases. Volumes in the Series
Author: Harold Morris
Author: Harold Morris
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Author: National Cancer Institute (U.S.)
Author: Philip G. Stansly
Author: Roeland van Wijk
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Author: 
Author: National Institutes of Health (U.S.). Division of Research Grants
Author: I. Bekhor Isaac
Author: M. A. Hayat