Moments of Discovery PDF Download

Author: Eliot Porter
Publisher:
ISBN:
Category : Bird watching
Languages : en
Pages : 0

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Author: Eugene H. Cordes
Publisher: Oxford University Press, USA
ISBN: 0190080450
Category : Medical
Languages : en
Pages : 333

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Book Description
"This work provides eleven stories of drug discovery and features the scientists who made them. The outcome of the discovery work has provided novel therapies in cancer, cardiovascular medicine, antibacterial and antiviral infectious diseases, parasitic diseases, metabolic diseases, and weight control. Each story begins with the basic biomedical science that revealed the pathway to effective drug therapy and continues with the step-by-step process that leads from insight to a product in clinical practice meeting a defined medical need. The tales feature creative problem solving by clever and dedicated scientists as they overcame roadblocks to success., hallelujah moments. Each drug discovery story reflects the interface between basic science, medicine, and drug discovery. Embedded in these tales are the societal and medical environments in which drug discovery takes place, the discovery of agents to treat HIV/AIDS, for example. Finally, a series of appendices provides basic chemical background for non-scientists"--

Author: George I. Schwartz
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 536

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Author: Virginia Woolf
Publisher: Houghton Mifflin Harcourt
ISBN: 9780156619189
Category : Biography & Autobiography
Languages : en
Pages : 236

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Book Description
Published years after her death, Moments of Being is Virginia Woolf's only autobiographical writing, considered by many to be her most important book. A collection of five memoir pieces written for different audiences spanning almost four decades, Moments of Being reveals the remarkable unity of Virginia Woolf's art, thought, and sensibility. "Reminiscences," written during her apprenticeship period, exposes the childhood shared by Woolf and her sister, Vanessa, while "A sketch of the Past" illuminates the relationship with her father, Leslie Stephens, who played a crucial role in her development as an individual a writer. Of the final three pieces, composed for the Memoir Club, which required absolute candor of its members, two show Woolf at the threshold of artistic maturity and one shows a confident writer poking fun at her own foibles.

Author: Jie Jack Li
Publisher: John Wiley & Sons
ISBN: 111835446X
Category : Medical
Languages : en
Pages : 572

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Book Description
Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design. Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contributions are based on a thorough review of the current literature as well as the authors' firsthand laboratory experience in drug discovery. The book begins with the history of drug discovery, describing groundbreaking moments in the field. Next, it covers such topics as: Target identification and validation Drug metabolism and pharmacokinetics Central nervous system drugs In vitro and in vivo assays Cardiovascular drugs Cancer drugs Each chapter features a case study, helping readers understand how science is put into practice throughout all phases of drug discovery. References at the end of each chapter serve as a gateway to groundbreaking original research studies and reviews in the field. Drug Discovery is ideal for newcomers to medicinal chemistry and drug discovery, providing a comprehensive overview of the field. Veterans in the field will also benefit from the perspectives of leading international experts in all aspects of drug discovery.

Author: Rosebud Ben-Oni
Publisher: Alice James Books
ISBN: 1948579499
Category : Poetry
Languages : en
Pages : 88

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A fascinating blend of poetry and science, Ben-Oni’s poems are precisely crafted, like a surgeon sewing a complicated stitch. The speaker of the collection falls ill, and takes comfort in exploring the idea of “Efes” which is “zero” in Modern Hebrew, using that nullification to be a means of transformation.

Author: Thomas Nickles
Publisher: Taylor & Francis
ISBN: 9789027710925
Category : History
Languages : en
Pages : 418

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Book Description
The history of science is articulated by moments of discovery. Yet, these 'moments' are not simple or isolated events in science. Just as a scientific discovery illuminates our understanding of nature or of society, and reveals new connections among phenomena, so too does the history of scientific activity and the analysis of scientific reasoning illuminate the processes which give rise to moments of discovery and the complex network of consequences which follow upon such moments. Understanding discovery has not been, until recently, a major concern of modem philosophy of science. Whether the act of discoyery was regarded as mysterious and inexplicable, or obvious and in no need of explanation, modem philosophy of science in effect bracketed the question. It concentrated instead on the logic of scientific explanation or on the issues of validation or justification of scientific theories or laws. The recent revival of interest in the context of discovery, indeed in the acts of discovery, on the part of philosophers and historians of science, represents no one particular method'ological or philosophical orientation. It proceeds as much from an empiricist and analytical approach as from a sociological or historical one; from considerations of the logic of science as much as from the alogical or extralogical contexts of scientific tho'¢tt and practice. But, in general, this new interest focuses sharply on the actual historical and contem porary cases of scientific discovery, and on an examination of the act or moment of discovery in situ.

Author: Peter Reich
Publisher: Peter Reich
ISBN: 1458179281
Category : Biography & Autobiography
Languages : en
Pages : 106

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Author: Gillian Siddall
Publisher: Duke University Press
ISBN: 0822374498
Category : Music
Languages : en
Pages : 376

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Book Description
The contributors to Negotiated Moments explore how subjectivity is formed and expressed through musical improvisation, tracing the ways the transmission and reception of sound occur within and between bodies in real and virtual time and across memory, history, and space. They place the gendered, sexed, raced, classed, disabled, and technologized body at the center of critical improvisation studies and move beyond the field's tendency toward celebrating improvisation's utopian and democratic ideals by highlighting the improvisation of marginalized subjects. Rejecting a singular theory of improvisational agency, the contributors show how improvisation helps people gain hard-won and highly contingent agency. Essays include analyses of the role of the body and technology in performance, improvisation's ability to disrupt power relations, Pauline Oliveros's ideas about listening, flautist Nicole Mitchell's compositions based on Octavia Butler's science fiction, and an interview with Judith Butler about the relationship between her work and improvisation. The contributors' close attention to improvisation provides a touchstone for examining subjectivities and offers ways to hear the full spectrum of ideas that sound out from and resonate within and across bodies. Contributors. George Blake, David Borgo, Judith Butler, Rebecca Caines, Louise Campbell, Illa Carrillo Rodríguez, Berenice Corti, Andrew Raffo Dewar, Nina Eidsheim, Tomie Hahn, Jaclyn Heyen, Christine Sun Kim, Catherine Lee, Andra McCartney, Tracy McMullen, Kevin McNeilly, Leaf Miller, Jovana Milovic, François Mouillot, Pauline Oliveros, Jason Robinson, Neil Rolnick, Simon Rose, Gillian Siddall, Julie Dawn Smith, Jesse Stewart, Clara Tomaz, Sherrie Tucker, Lindsay Vogt, Zachary Wallmark, Ellen Waterman, David Whalen, Pete Williams, Deborah Wong, Mandy-Suzanne Wong

Author: Tim Shapiro
Publisher: Rowman & Littlefield
ISBN: 1566997453
Category : Religion
Languages : en
Pages : 187

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Book Description
Change isn’t always easy or intuitive. How Your Congregation Learns introduces churches and leaders—both lay and ordained—to the process of the learning journey. By understanding learning dynamics and working to become a learning community, the congregation will be able to move more purposefully to achieve its goals. Congregations face many kinds of challenges. Some are mundane: the roof leaks; the parking lot needs repaving; the microphones don’t work well. Some tests are transcendent: How should lives be honored? What is God calling the congregation to do and be? How can generosity be taught? Throughout life people face challenges for which they are not prepared—the death of a parent, a new job offer, making a decision about where to live. So it goes that congregational leaders face challenges that are just beyond the grasp of their abilities. This book addresses the just-beyond-the-grasp challenges and shows how real congregations can learn from them.