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Author: Sergej M. Ostojic Publisher: Academic Press ISBN: 0323984525 Category : Science Languages : en Pages : 714
Book Description
Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals provides a comprehensive examination of molecular aspects of mitochondrial nutrition and how dietary compounds might impact the treatment of mitochondrial dysfunction. Beginning with an overview of the fundamentals of mitochondria physiology and the methods used to evaluate mitochondrial imbalance in clinical practice, the book goes on to outline nutritional shortfalls in mitochondrial dysfunction and highlights the complex intra-organelle milieu affecting interactions between food compounds and mitochondrial co-factors, metabolites, and signaling molecules. Further sections explore the impact of essential nutrients, such as vitamin E, fatty acids, and complex lipids, on mitochondrial biogenesis, as well as non-essential bioactive compounds originating from food that can be evaluated for their mitochondria-modulating potential, such as mitochondria-targeted small molecule antioxidants, plant-based pigments and organic compounds, nucleotides, non-proteogenic amino acids and derivatives, and mitochondria-specific enzyme mimetics from food. Molecular Nutrition and Mitochondria covers the key impacts of nutrition on mitochondria, and is the ideal reference for researchers, students and clinicians looking to develop an in-depth understanding of how dietary compounds can prevent and treat disorders associated with mitochondrial dysfunction. - Describes the fundamentals of mitochondria physiology and considers the methods used to evaluate mitochondrial imbalance in clinical practice - Provides broad biochemical and metabolic background on nutritional deficits found in mitochondrial dysfunction - Explores the prevention and treatment of various inherited and acquired disorders associated with mitochondrial dysfunction - Discusses the link between the dosage for each nutrient (nutritional vs. pharmacological) and the clinical effect - Features a dedicated section on whole-diet interventions and mitochondrial function
Author: Sergej M. Ostojic Publisher: Academic Press ISBN: 0323984525 Category : Science Languages : en Pages : 714
Book Description
Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals provides a comprehensive examination of molecular aspects of mitochondrial nutrition and how dietary compounds might impact the treatment of mitochondrial dysfunction. Beginning with an overview of the fundamentals of mitochondria physiology and the methods used to evaluate mitochondrial imbalance in clinical practice, the book goes on to outline nutritional shortfalls in mitochondrial dysfunction and highlights the complex intra-organelle milieu affecting interactions between food compounds and mitochondrial co-factors, metabolites, and signaling molecules. Further sections explore the impact of essential nutrients, such as vitamin E, fatty acids, and complex lipids, on mitochondrial biogenesis, as well as non-essential bioactive compounds originating from food that can be evaluated for their mitochondria-modulating potential, such as mitochondria-targeted small molecule antioxidants, plant-based pigments and organic compounds, nucleotides, non-proteogenic amino acids and derivatives, and mitochondria-specific enzyme mimetics from food. Molecular Nutrition and Mitochondria covers the key impacts of nutrition on mitochondria, and is the ideal reference for researchers, students and clinicians looking to develop an in-depth understanding of how dietary compounds can prevent and treat disorders associated with mitochondrial dysfunction. - Describes the fundamentals of mitochondria physiology and considers the methods used to evaluate mitochondrial imbalance in clinical practice - Provides broad biochemical and metabolic background on nutritional deficits found in mitochondrial dysfunction - Explores the prevention and treatment of various inherited and acquired disorders associated with mitochondrial dysfunction - Discusses the link between the dosage for each nutrient (nutritional vs. pharmacological) and the clinical effect - Features a dedicated section on whole-diet interventions and mitochondrial function
Author: Ray Griffiths Publisher: Singing Dragon ISBN: 0857012886 Category : Health & Fitness Languages : en Pages : 338
Book Description
What are the functions of mitochondria in the human body? Why might they stop working properly and what can happen as a result? How can personalized nutrition help to optimize mitochondrial function and prevent or address chronic conditions? This innovative book explores the incredibly complex biochemical roles of mitochondria in health and disease. When healthy, mitochondria provide us with ninety percent of our body's energy. When unhealthy, this can lead to many chronic and degenerative conditions including cancer and Alzheimer's disease. This guide helps practitioners to identify the mitochondrial dysfunction underlying a wide range of health complaints, and provides inspiration about relevant and emerging mitochondria-supportive dietary regimes and nutrients to explore within the model of personalized nutrition.
Author: Martha H. Stipanuk Publisher: Saunders ISBN: Category : Medical Languages : en Pages : 1244
Book Description
Presents advanced nutrition in a comprehensive format ideal for graduate students in nutritional programs, organic chemistry, physiology, biochemistry and molecular biology. Focuses on the biology of human nutrition at the molecular, cellular, tissue and whole-body levels.
Author: Manlio Vinciguerra Publisher: Academic Press ISBN: 0128138637 Category : Technology & Engineering Languages : en Pages : 450
Book Description
Molecular Nutrition: Mother and Infant presents the impact of diet in early life stages, from pre-conception, throughout pregnancy, and to the infant. The book covers the molecular biology of the cell, genetic machinery and its function, general coverage on diet and nutrition, pregnancy, placenta, weight gain, breast milk, feeding practices, gestational disease, glucose metabolism, immunity, vitamins and minerals. Other topics discusses include fetal programming, bioactive compounds, amino acids, intrauterine growth, one carbon metabolism, overnutrition, genetic risk factors, polymorphisms, folic acid genes, DNA methylation, genes involved in lipid metabolism, microRNAs, epigenetics, transcriptomics and micro RNA. This book will be a welcomed reference for research scientists and practitioners, including nutritionists and dieticians. Addresses mother and infant nutrition and its critical impact on the well-being of humankind Contains coverage from pre-conception to young offspring Includes pedagogical features (e.g. a list of key facts, mini-dictionaries of terms and definitions, and summary points) to assist in its use as a reference Contains coverage of emerging fields of molecular biology and important discoveries related to diet and nutritional health
Author: F. Palmieri Publisher: Newnes ISBN: 0444599827 Category : Science Languages : en Pages : 279
Book Description
The topics contained in this book represent timely and currently exciting areas of research focused on mitochondria. It forms a comprehensive and up-to-date record of present knowledge at the molecular level of many important mitochondrial processes. Major achievements as well as new openings in the field have been stressed in many of the contributions to the book. Thus, it represents a valuable source and reference book, comprising the most recent results in this area. The topics treated should attract the attention of scientists from various fields, who are interested in bioenergetics, molecular biology and pathology of mitochondria.
Author: Didac Mauricio Publisher: Academic Press ISBN: 0128017619 Category : Medical Languages : en Pages : 400
Book Description
Molecular Nutrition and Diabetes: A Volume in the Molecular Nutrition Series focuses on diabetes as a nutritional problem and its important metabolic consequences. Fuel metabolism and dietary supply all influence the outcome of diabetes, but understanding the pathogenesis of the diabetic process is a prelude to better nutritional control. Part One of the book provides general coverage of nutrition and diabetes in terms of dietary patterns, insulin resistance, and the glucose-insulin axis, while Part Two presents the molecular biology of diabetes and focuses on areas such as oxidative stress, mitochondrial function, insulin resistance, high-fat diets, nutriceuticals, and lipid accumulation. Final sections explore the genetic machinery behind diabetes and diabetic metabolism, including signaling pathways, gene expression, genome-wide association studies, and specific gene expression. While the main focus of each chapter is the basic and clinical research on diabetes as a nutritional problem, all chapters also end with a translational section on the implications for the nutritional control of diabetes. - Offers updated information and a perspective on important future developments to different professionals involved in the basic and clinical research on all major nutritional aspects of diabetes mellitus - Explores how nutritional factors are involved in the pathogenesis of both type1 and type2 diabetes and their complications - Investigates the molecular and genetic bases of diabetes and diabetic metabolism through the lens of a rapidly evolving field of molecular nutrition
Author: Peter Sutovsky Publisher: Springer ISBN: 3030045706 Category : Science Languages : en Pages : 126
Book Description
This new volume of our successful book series Advances in Anatomy, Embryology and Cell Biology is focused on mitochondrial inheritance in humans and both vertebrate and invertrebate animals including Drosophila, C. elegans, bivalve molusc Mytilus and livestock mammals. Special consideration is given to cellular mechanisms promoting uniparental inheritance of mitochondria and mitochondrial genes, evolutionary perspectives, and biomedical and epidemiological considerations. Contributed by five distinguished mitochondrial research teams from around the world, this volume will target a wide audience of physiologists, anatomists, cell, and developmental and evolutionary biologists, as well as physicians, veterinarians, livestock specialists and biomedical researchers.
Author: Aysegul Coruhlu Publisher: ISBN: 9781659507904 Category : Languages : en Pages : 192
Book Description
Human beings produce energy according to quantum principles. Therefore, human beings need to eat what is consistent with quantum biology. Human beings must eat quantum.This book will help you to eat in a way that is appropriate for the biology of our mitochondria-our source of life, our energy engines. The thousands of mitochondria in each of our cells are there only for us to produce energy. Altogether they number trillions, and we are dependent on them.- Even a strand of our hair cannot grow without the energy from mitochondria. - Our aging cells cannot be renewed without the energy produced by mitochondria.- We will not recover from diseases if mitochondria do not produce energy. We are dependent on that energy for something as simple as blinking an eye and something as vital as our immune system intercepting a cancer cell. All our life functions are dependent on that energy. We must secure that energy. And what's more, we must do this for every second of twenty-four hours a day. We must do whatever it takes for our mitochondria to produce that energy for us. We must give whatever source of energy they choose as fuel to these energy engines. Otherwise, we shall die. Our afflictions in illness and cures in treatment are the same for all of us: choosing the most appropriate fuel for our mitochondrial engine, so that it may produce the best energy. That is our fundamental task. That is our prime concern. The best fuel is the most appropriate one (nothing more) for our mitochondria's biology, our mitochondria's quantum biology. Classical biology is now inadequate in explaining the complex energy production in mitochondria. The new biology is quantum biology.If we want to stay alive for many years and live a healthy life, we cannot go against the unequivocal principles of biology. We receive energy that supplies our vitality according to quantum biological principles of mitochondria. In other words, we must abide by the rules of quantum biology. The medicine of the future will merely be to prevent initial damage. In the future, physicians will not be diagnosing diseases.Consequently, there will no longer be such a thing as curing diseases. Medicine, biophysics, biomedicine, quantum physics, and electronics will be intertwined, and the system faults will be dealt with at micro and molecular levels. There will be a greater need for quantum biologists than for surgeons.These are not exaggerations, they just need broader thinking. Since we accept that we are biological creatures, we must stop ignoring the biology of our smallest units-the cells, and the organelles inside them. The secret that makes the human being a special living species is hidden in the system inside these cells. The cells' own inner processes, energy production, intercellular communication, the cell systems' functioning as a whole, the cells being synchronized with the earth, sun, and universe occur entirely according to the rules of quantum biology. These are subatomic events that seem strange to us.Subatomic little particles (not just electrons and protons but quarks, tachyons, etc.) and information about their effects on health and vitality will in time be a source of amazement.Throughout this book, I have only attempted to clarify matters at the cell and mitochondria levels-the deepest points to which we can go down. If we can understand even this much, we can establish the link between our health and getting ill.
Author: Tatiana K. Rostovtseva Publisher: Springer ISBN: 3319555391 Category : Science Languages : en Pages : 388
Book Description
This book covers recent advances in the study of structure, function, and regulation of metabolite, protein and ion translocating channels, and transporters in mitochondria. A wide array of cutting-edge methods are covered, ranging from electrophysiology and cell biology to bioinformatics, as well as structural, systems, and computational biology. At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established. After years of work on the physiology and structure of VDAC channels in the mitochondrial outer membrane, there have been multiple discoveries on VDAC permeation and regulation by cytosolic proteins. Recent breakthroughs in structural studies of the mitochondrial cholesterol translocator reveal a set of novel unexpected features and provide essential clues for defining therapeutic strategies. Molecular Basis for Mitochondrial Signaling covers these and many more recent studies of mitochondria function, their communication with other organelles, and their critical roles in development, aging, and in a plethora of stressful or degenerative events. Authored by leading researchers in the field, this volume will be an indispensable reference resource for graduate students and academics working in related areas of biophysics and cell biology as well as for professionals within industry.
Author: Sergej M. Ostojic
Author: Sergej M. Ostojic
Author: Ray Griffiths
Author: Martha H. Stipanuk
Author: 
Author: Manlio Vinciguerra
Author: F. Palmieri
Author: Didac Mauricio
Author: Peter Sutovsky
Author: Aysegul Coruhlu
Author: Tatiana K. Rostovtseva