Author: Jure Piškur Publisher: Springer ISBN: 3642550134 Category : Science Languages : en Pages : 328
Book Description
Yeast is one of the most studied laboratory organisms and represents one of the most central models to understand how any eukaryote cell works. On the other hand, yeast fermentations have for millennia provided us with a variety of biotech products, like wine, beer, vitamins, and recently also with pharmaceutically active heterologous products and biofuels. A central biochemical activity in the yeast cell is the metabolism of carbon compounds, providing energy for the whole cell, and precursors for any of the final fermentation products. A complex set of genes and regulatory pathways controls the metabolism of carbon compounds, from nutrient sensing, signal transduction, transcription regulation and post-transcriptional events. Recent advances in comparative genomics and development of post-genomic tools have provided further insights into the network of genes and enzymes, and molecular mechanisms which are responsible for a balanced metabolism of carbon compounds in the yeast cell, and which could be manipulated in the laboratory to increase the yield and quality of yeast biotech products. This book provides a dozen of most comprehensive reviews on the recent developments and achievements in the field of yeast carbon metabolism, from academic studies on gene expression to biotechnology relevant topics.
Author: Jared William Wenger Publisher: Stanford University ISBN: Category : Languages : en Pages : 122
Book Description
The processes by which the budding yeast Saccharomyces cerevisiae metabolizes carbon sources by both fermentation and respiration have been studied for more than a century. Yeast metabolism has been used both industrially, for the production of important molecules such as ethanol, and as a model for basic scientific research. Applied scientists have studied yeast metabolism to create and optimize novel metabolic phenotypes not naturally found in Saccharomyces yeasts. In parallel, basic scientists have used yeast as a model to understand fundamental processes such as evolutionary adaptation, as well as the pathways of carbon metabolism themselves. There are many unanswered questions in both of these fields, some of which I have addressed in this work. With respect to the industrial importance of yeast, I asked whether there are naturally existing Saccharomyces yeasts that can metabolize the five-carbon sugars important for lignocellulosic ethanol production (such as xylose), and, if so, what is the genetic basis for their phenotypes? Having characterized natural genetic variation in xylose metabolism, I also wanted to understand something more fundamental about how carbon metabolism can adapt, including the molecular nature of adaptations to selection on a limiting carbon source. Specifically, I asked what is the niche breadth of, and are there genetic trade-offs in, yeast that have been evolved under glucose-limitation? I have used a combination of classical genetics, physiology, and high-throughput genomics to answer these two questions. I have discovered novel xylose-utilizing Saccharomyces yeasts and have shed considerable light on the genetic basis for their phenotypes. In addition, I have discovered at least one trade-off for adaptation to limiting glucose, namely that amplification of the hexose-transporter genes HXT6 and HXT7 causes reduced fitness in carbon-rich environments. These two projects highlight two major spheres of Saccharomyces research, and they provide key answers to outstanding questions in both fields.
Author: Jared William Wenger Publisher: ISBN: Category : Languages : en Pages :
Book Description
The processes by which the budding yeast Saccharomyces cerevisiae metabolizes carbon sources by both fermentation and respiration have been studied for more than a century. Yeast metabolism has been used both industrially, for the production of important molecules such as ethanol, and as a model for basic scientific research. Applied scientists have studied yeast metabolism to create and optimize novel metabolic phenotypes not naturally found in Saccharomyces yeasts. In parallel, basic scientists have used yeast as a model to understand fundamental processes such as evolutionary adaptation, as well as the pathways of carbon metabolism themselves. There are many unanswered questions in both of these fields, some of which I have addressed in this work. With respect to the industrial importance of yeast, I asked whether there are naturally existing Saccharomyces yeasts that can metabolize the five-carbon sugars important for lignocellulosic ethanol production (such as xylose), and, if so, what is the genetic basis for their phenotypes? Having characterized natural genetic variation in xylose metabolism, I also wanted to understand something more fundamental about how carbon metabolism can adapt, including the molecular nature of adaptations to selection on a limiting carbon source. Specifically, I asked what is the niche breadth of, and are there genetic trade-offs in, yeast that have been evolved under glucose-limitation? I have used a combination of classical genetics, physiology, and high-throughput genomics to answer these two questions. I have discovered novel xylose-utilizing Saccharomyces yeasts and have shed considerable light on the genetic basis for their phenotypes. In addition, I have discovered at least one trade-off for adaptation to limiting glucose, namely that amplification of the hexose-transporter genes HXT6 and HXT7 causes reduced fitness in carbon-rich environments. These two projects highlight two major spheres of Saccharomyces research, and they provide key answers to outstanding questions in both fields.
Author: Friedrich K. Zimmermann Publisher: CRC Press ISBN: 9781566764667 Category : Technology & Engineering Languages : en Pages : 590
Book Description
Yeast Sugar Metabolism looks at the biomechanics, genetics, biotechnology and applications of yeast sugar. The yeast Saccharomyces cereisiae has played a central role in the evolution of microbiology biochemistry and genetics, in addition to its use of a technical microbe for the production of alcoholic beverages and leavening of dough.
Author: Helmut König Publisher: Springer ISBN: 3319600214 Category : Technology & Engineering Languages : en Pages : 711
Book Description
The second edition of the book begins with the description of the diversity of wine-related microorganisms, followed by an outline of their primary and energy metabolism. Subsequently, important aspects of the secondary metabolism are dealt with, since these activities have an impact on wine quality and off-flavour formation. Then chapters about stimulating and inhibitory growth factors follow. This knowledge is helpful for the growth management of different microbial species. The next chapters focus on the application of the consolidated findings of molecular biology and regulation the functioning of regulatory cellular networks, leading to a better understanding of the phenotypic behaviour of the microbes in general and especially of the starter cultures as well as of stimulatory and inhibitory cell-cell interactions during wine making. In the last part of the book, a compilation of modern methods complete the understanding of microbial processes during the conversion of must to wine.This broad range of topics about the biology of the microbes involved in the vinification process could be provided in one book only because of the input of many experts from different wine-growing countries.
Author: Ram Prasad Publisher: Springer ISBN: 3319773860 Category : Science Languages : en Pages : 401
Book Description
Bioremediation is the use of microorganisms' metabolism to degrade waste contaminants (sewage, domestic, and industrial effluents) into non-toxic or less toxic materials by natural biological processes. Volume 2 offers new discussion of remediation through fungi—or mycoremediation—and its multifarious possibilities in applied remediation engineering and the future of environmental sustainability. Fungi have the biochemical and ecological capability to degrade environmental organic chemicals and to decrease the risk associated with metals, semi-metals, noble metals, and radionuclides, either by chemical modification or by manipulating chemical bioavailability. Additional expanded texts shows the capability of these fungi to form extended mycelia networks, the low specificity of their catabolic enzymes, and their use against pollutants as a growth substrate, making these fungi well suited for bioremediation processes. Their mycelia exhibit the robustness of adapting to highly limiting environmental conditions often experienced in the presence of persistent pollutants, which makes them more useful compared to other microbes. Despite dominating the living biomass in soil and being abundant in aquatic ecosystems, however, fungi have not been exploited for the bioremediation of such environments until this added Volume 2. This book covers the various types of fungi and associated fungal processes used to clean up waste and wastewaters in contaminated environments and discusses future potential applications.
Author: Sérgio Luiz Alves Júnior Publisher: Bentham Science Publishers ISBN: 9815051075 Category : Science Languages : en Pages : 494
Book Description
Since ancient times, yeasts have been used for brewing and breadmaking processes. They now represent a flagship organism for alcoholic fermentation processes. The ubiquity of some yeast species also offers microbiologists a heterologous gene-expression platform, making them a model organism for studying eukaryotes. Yeasts: from Nature to Bioprocesses brings together information about the origin and evolution of yeasts, their ecological relationships, and the main taxonomic groups into a single volume. The book initially explores six significant yeast genera in detailed chapters. The book then delves into the main biotechnological processes in which both prospected and engineered yeasts are successfully employed. Yeasts: from Nature to Bioprocesses, therefore, elucidates the leading role of these single-cell organisms for industrial microbiology in environmental, health, social, and economic terms. This book is a comprehensive, multidisciplinary resource for general readers as well as scholars of all levels who want to know all about yeast microbiology and their industrial applications.
Author: Rouf Ahmad Bhat Publisher: Springer Nature ISBN: 3030940748 Category : Science Languages : en Pages : 173
Book Description
This volume discusses how plant and algae organisms play a pivotal role in the transformation of solar energy to essential metabolites, and explores the numerous beneficial roles these metabolites have at an industrial level. It presents information on the utilization of plant and algae for biomass production, and shows how this is a practical option for large scale biofuel production. The book examines how these bio-metabolites can then be used to extract biofuel. Biomass produced from plants and algae can act as the source of feedstock for biofuel production and industrially important compounds. This book also explores that by curtailing culturing cost using wastewater, seawater, and industrial water as a nutrient and water source, biomass becomes an economical energy source. The introductory chapters of the book focus on the appreciative values of a pollution-free atmosphere, with special reference to enhanced greenhouse effect, and then are followed by chapters on the potential of plant and algae as a liquid energy resource. This book targets researchers, graduate students, and energy and fuel industry professionals interested in the plant sciences, biotechnology and renewable energy.
Author: Otto Geiger Publisher: Springer ISBN: 9783319504292 Category : Science Languages : en Pages : 0
Book Description
Concise chapters, written by experts in the field, cover a wide spectrum of topics on lipid and membrane formation in microbes (Archaea, Bacteria, eukaryotic microbes).All cells are delimited by a lipid membrane, which provides a crucial boundary in any known form of life. Readers will discover significant chapters on microbial lipid-carrying biomolecules and lipid/membrane-associated structures and processes.
Author: Jure Piškur
Author: Jared William Wenger
Author: Jared William Wenger
Author: Friedrich K. Zimmermann
Author: Helmut König
Author: Bruce Alberts
Author: Ram Prasad
Author: Sérgio Luiz Alves Júnior
Author: Rouf Ahmad Bhat
Author: Otto Geiger