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Author: Herbert Taylor Publisher: Elsevier ISBN: 0323146848 Category : Science Languages : en Pages : 534
Book Description
Molecular Genetics, Part II covers the significant developments in various areas of molecular genetics. This book is composed of 10 chapters that also consider the gene expression and regulation of some enzymes. The opening chapters deal with the mechanisms of nucleic acid replication and repair, as well as the structural aspects of the genetic apparatus of viruses and cells. The next chapters explore the patterns and mechanisms of genetic recombination, the in vitro and in vivo experiments to delineate the genetic code, and the initiation of peptide chains in Escherichia coli. These topics are followed by discussions of the mechanism of DNA-dependent RNA synthesis, the regulation of enzyme synthesis in microorganisms, and the regulation of viral replication. The final chapters consider the theoretical and practical aspects of the metabolic regulation in metazoan system and the procedures for the study of DNA-DNA and DNA-RNA interactions. This book will be of great value to molecular geneticists, biochemists, and researchers.
Author: Herbert Taylor Publisher: Elsevier ISBN: 0323146848 Category : Science Languages : en Pages : 534
Book Description
Molecular Genetics, Part II covers the significant developments in various areas of molecular genetics. This book is composed of 10 chapters that also consider the gene expression and regulation of some enzymes. The opening chapters deal with the mechanisms of nucleic acid replication and repair, as well as the structural aspects of the genetic apparatus of viruses and cells. The next chapters explore the patterns and mechanisms of genetic recombination, the in vitro and in vivo experiments to delineate the genetic code, and the initiation of peptide chains in Escherichia coli. These topics are followed by discussions of the mechanism of DNA-dependent RNA synthesis, the regulation of enzyme synthesis in microorganisms, and the regulation of viral replication. The final chapters consider the theoretical and practical aspects of the metabolic regulation in metazoan system and the procedures for the study of DNA-DNA and DNA-RNA interactions. This book will be of great value to molecular geneticists, biochemists, and researchers.
Author: Herbert Taylor Publisher: Elsevier ISBN: 0323151876 Category : Science Languages : en Pages : 407
Book Description
Molecular Genetics, Part III: Chromosome Structure explores the structure and modification of DNA, chromatin, and higher order organization and possible subunits of chromosomes at the molecular level. It describes major changes in concepts of chromatin structure and packaging of DNA based on studies of nuclease digests and electron micrographs; the role of restriction endonucleases in molecular genetics; the involvement of DNA topoisomerases in concerted breaking and rejoining of DNA backbone bonds; enzymatic methylation of DNA; and transcriptional units in eukaryotic chromosomes. Organized into seven chapters, this volume begins with an overview of the general properties of type I and type II restriction enzymes, basic aspects of restriction enzyme technology, and applications of restriction enzyme technology to the study of chromosome structure and function. It then discusses recombinant DNA technology; possible biological roles of DNA topoisomerases; recognition and control sequences in nucleic acids; composition and substructure of nucleosomes; analysis of chromosome fibers by electron microscopy; organization of fibers into chromosomes; and functional aspects of organization of chromosome fibers. Molecular biologists, geneticists, scientists, and electron microscopists will find this book extremely helpful.
Author: Charles R. Scriver Publisher: New York ; Montreal : McGraw-Hill ISBN: 9780071363198 Category : Genetic disorders Languages : en Pages : 6338
Book Description
Presents clinical, biochemical, and genetic information concerning those metabolic anomalies grouped under inborn errors of metabolism.
Author: National Research Council Publisher: National Academies Press ISBN: 0309134404 Category : Science Languages : en Pages : 270
Book Description
In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.
Author: T A Brown Publisher: Garland Science ISBN: 1136665358 Category : Science Languages : en Pages : 554
Book Description
Introduction to Genetics: A Molecular Approach is a new textbook for first and second year undergraduates. It first presents molecular structures and mechanisms before introducing the more challenging concepts and terminology associated with transmission genetics.
Author: Rathan Subramaniam Publisher: Elsevier Health Sciences ISBN: 0323546811 Category : Medical Languages : en Pages :
Book Description
This issue of PET Clinics focuses on Molecular Imaging and Precision Medicine, Part II, and is edited by Dr. Rathan Subramaniam. Articles will include: Precision Medicine in Esophageal Cancer; Precision Medicine and PET/CT in Melanoma; Precision Medicine and PET/CT in Hepatobilliary and Pancreatic Cancer; Precision Medicine and PET/CT in Gastric Cancer; Precision Medicine and PET/CT in Skeletal and Soft Tissue Sarcomas; Precision Medicine and PET/MRI; Precision Medicine and PET/CT in Uterine and Ovarian Cancers; Precision Medicine and PET/CT in Cardiovascular Disorders, and more!
Author: Herbert Taylor
Author: Herbert Taylor
Author: Bruce Alberts
Author: 
Author: Herbert Taylor
Author: Charles R. Scriver
Author: National Research Council
Author: T A Brown
Author: Rathan Subramaniam
Author: Marjorie A. Hoy
Author: J.H. Taylor