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Author: Carol A. Wise Publisher: Springer ISBN: 149392169X Category : Medical Languages : en Pages : 173
Book Description
In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders. A few projects have even progressed into the realm of clinical trials that are primarily aimed at controlling progressive disease. Meanwhile, genomic technology development has outpaced expectations and is enabling gene discovery for disorders that were previously intractable with traditional genetic methods. Included in this latter category are common disorders that display multigenic inheritance, sporadic disorders, and very rare conditions that are difficult to ascertain. Simultaneously, the study of pediatric orthopaedic disorders has been continuously refined and updated, highlighting a number of likely genetic conditions that are as yet unsolved. Molecular Genetics of Pediatric Orthopaedic Disorders updates researchers and clinicians of new developments of pediatric orthopaedic genetics. The chapters inform the audience on the revolution in new genomic methods and the impact this is having on potential study designs and the potential to discover genetic causes of many unsolved orthopaedic conditions. Recent examples have been included of pediatric orthopaedic conditions, both rare and common, that are being solved with these new methods. The book also educates pediatric orthopedic clinicians and geneticists on our understanding of the biology of “classic” genetic diseases that were derived from prior genetic studies. Chapters include biobanks and strategies for studying very rare disorders, genes and pathways causing primordial dwarfism, and notch signaling in congenital scoliosis, and more.
Author: Carol A. Wise Publisher: Springer ISBN: 149392169X Category : Medical Languages : en Pages : 173
Book Description
In the past two decades we have seen a surge forward in understanding the genetics and biochemistry underlying many pediatric orthopaedic disorders. A few projects have even progressed into the realm of clinical trials that are primarily aimed at controlling progressive disease. Meanwhile, genomic technology development has outpaced expectations and is enabling gene discovery for disorders that were previously intractable with traditional genetic methods. Included in this latter category are common disorders that display multigenic inheritance, sporadic disorders, and very rare conditions that are difficult to ascertain. Simultaneously, the study of pediatric orthopaedic disorders has been continuously refined and updated, highlighting a number of likely genetic conditions that are as yet unsolved. Molecular Genetics of Pediatric Orthopaedic Disorders updates researchers and clinicians of new developments of pediatric orthopaedic genetics. The chapters inform the audience on the revolution in new genomic methods and the impact this is having on potential study designs and the potential to discover genetic causes of many unsolved orthopaedic conditions. Recent examples have been included of pediatric orthopaedic conditions, both rare and common, that are being solved with these new methods. The book also educates pediatric orthopedic clinicians and geneticists on our understanding of the biology of “classic” genetic diseases that were derived from prior genetic studies. Chapters include biobanks and strategies for studying very rare disorders, genes and pathways causing primordial dwarfism, and notch signaling in congenital scoliosis, and more.
Author: Ian D. Young Publisher: Remedica ISBN: 1901346420 Category : Orthopedic Languages : en Pages : 113
Book Description
Molecular biology is one of the fastest growing areas of medical research and now impinges on almost every medical discipline. This work provides an up-to-date overview of developments in molecular genetics as they relate to orthopedic practice.
Author: Frederic Shapiro Publisher: Elsevier ISBN: 0080538568 Category : Medical Languages : en Pages : 975
Book Description
Specific operative and nonoperative techniques and their results are stressed. The book is extensively illustrated with drawings, most of which were made for this book, microscopy photos, and serial radiographs. The reader learns of pediatric orthopedic deformity in relation to normal and abnormal developmental biology, the worsening of untreated disease with growth, and the diagnostic and treatment interventions required based on the stage of progression.* Treatments are correlated with the pathologic state of the disorder* Discusses disorders from earliest onset to the final state showing how the altered biology leads to progressively greater clinical deformity* Initial chapter focuses on development bone biology stressing a broad based approach involving histologic, gene and molecular, and biomechanical features* Subsequent chapters discuss the pathogenesis of the various deformities, natural history, radiographic and imaging findings and orthopaedic and surgical management
Author: Frederic Shapiro Publisher: Springer ISBN: 3319205293 Category : Medical Languages : en Pages : 807
Book Description
Developmental biology of normal bone and cartilage including histogenesis, molecular/gene and biomechanical aspects is updated and expanded. The book outlines the biology of: bone repair with differing mechanical environments; cartilage repair at articular and physeal sites; and distraction osteogenesis. The generously illustrated text provides an in-depth presentation of the interplay between normal developmental biology, abnormal pathologic states and the influence of operative and non-operative orthopedic interventions on childhood orthopedic deformity. Thirty-four principles underlying the development, progression and management of skeletal deformity in the growing child are defined. Orthopedic management including surgical treatment is discussed for: skeletal dysplasias; epiphyseal growth plate fracture-separations; lower extremity length discrepancies; and deformities of joints and epiphyses due to metabolic, inflammatory, infectious, hematologic, and neoplastic disorders. Treatments are related to extent of deformity, remodeling post-surgery and possible recurrence. This 2nd edition of Pediatric Orthopedic Deformities has been expanded to cover more regions and disorders and is being presented in 3 volumes.
Author: Publisher: Lippincott Williams & Wilkins ISBN: 1582558183 Category : Medical Languages : en Pages : 827
Book Description
Designed for general orthopedists, residents, pediatricians, physical therapists, and students, Practice of Pediatric Orthopedics, Second Edition is a practical, authoritative, generously illustrated, full-color how-to guide to the essentials of pediatric orthopedics. Dr. Staheli provides current, clinically proven, mainstream, whole child oriented management recommendations for musculoskeletal problems in children. The book features over 2,300 full-color photographs and drawings and numerous flowcharts to guide patient management. For this updated and expanded Second Edition, Dr. Staheli has recruited eight distinguished co-authors to contribute new information. Illustrations have been updated and many new illustrations have been added. The upper limb and hand chapters have been separated and expanded.
Author: J.G. Thometz Publisher: IOS Press ISBN: 1643681834 Category : Medical Languages : en Pages : 356
Book Description
It is over 70 years since two orthopedic surgeons invented the Milwaukee brace for the treatment of children with scoliosis. Since then, clinicians and researchers have been inspired to design ever more effective braces to correct 3-D spinal deformities. This book presents papers from the bi-annual meeting of the International Research Society of Spinal Deformities (IRSSD), held as a virtual event on 22 and 23 January 2021. The IRSSD concentrates on research into spinal deformity with clinical applications. In addition to 3D assessment of the spine, researchers also explore spinal biomechanics, etiopathogenesis, and innovative conservative and surgical therapies with the goal of integrating science with clinical care to improve patient care. The 2021 meeting was originally scheduled to take place in Milwaukee, Wisconsin, USA, but was instead held in a virtual format due to the Covid 19 pandemic. Despite this change, the meeting still allowed valuable interaction and open discussion among practitioners from around the world, and keynote speakers and authors contributed the 44 short papers and 47 abstracts included here. The papers are grouped under 17 chapter headings, and cover a wide range of topics, including biologic and biomechanical benchmarks, clinical evaluation, conservative treatments and surgical approaches. Diagnostic assessments and non-surgical treatments of EOS are also emphasized and elucidated. The book will be of interest to all those whose work is related to the treatment and care of patients with spinal deformities.
Author: John M. Flynn Publisher: Lippincott Williams & Wilkins ISBN: 1975108671 Category : Medical Languages : en Pages : 6466
Book Description
The gold standard comprehensive reference in pediatric orthopaedics is a must-have resource for physicians and residents treating infants, children, and adolescents with orthopaedic problems. Lovell and Winter’s Pediatric Orthopaedics, 8th Edition, brings you fully up to date in the field with new content, a new editor, and many new contributing authors who cover all aspects of basic science, clinical manifestations, and management. You’ll find complete, expert coverage of normal musculoskeletal development and the causes, diagnosis, and treatment of the entire range of abnormalities, with emphasis on evidence-based decision making in treatment selection.
Author: John A. Herring Publisher: Elsevier Health Sciences ISBN: 1455737402 Category : Medical Languages : en Pages : 2662
Book Description
Continuing the tradition of excellence that began in 1972, this latest edition of Tachdjian?s Pediatric Orthopaedics offers the detailed visual guidance; and unmatched expertise you need to effectively diagnose and treat pediatric musculoskeletal disorders. Extensive updates offer you the latest knowledge on etiology, imaging, differential diagnosis, and non-operative and surgical techniques for a wide range of pediatric orthopaedic conditions. "... delivers the most comprehensive text on this subject." Reviewed by Dr. Neel Kamal on behalf of BACCH Newsletter, March 2015 Access expert guidance on difficult diagnostic and clinical management issues for your most challenging cases. Perfect your technique with the visual guidance of nearly 2,500 full-color illustrations and 60 videos of pediatric surgical procedures, including a number that highlight clinical examination and unusual clinical findings. Produce the best possible outcomes using today's most effective approaches for management of severe spinal deformities, hip impingement, early-onset scoliosis, and other pediatric musculoskeletal conditions. See exactly how to proceed step-by-step with instructional videos demonstrating repair of bilateral dislocated hips, triple arthrodesis for planovalgus foot, patellofemoral ligament reconstruction, elbow arthroscopy, and more. Access the full contents online at Expert Consult.
Author: Paul Haynes Publisher: Elsevier Health Sciences ISBN: 0323710433 Category : Medical Languages : en Pages :
Book Description
In collaboration with Consulting Editor, Dr. Bonita Stanton, Dr. Paul Haynes has assembled expert authors to bring current information to pediatricians on the topic of Pediatric Orthopedics. The issue provides a general overview of evaluation and treatment of the pediatric orthopedic patients. Specific articles are devoted to the following topics: Evaluation: Pediatric Orthopedic Exam; Genetic and Metabolic Conditions; Musculoskeletal Infections; Neuromuscular Conditions - Orthopedic Manifestations; Pediatric Anesthesia as Related To Orthopedic Procedures -Perioperative Management; The Limping Child; Pediatric Orthopedic Trauma; Hand and Upper Extremity; Hip and Pelvis; Knee and Lower Extremity; Foot and Ankle; Pediatric Spine; Pediatric Sports Injuries; Concussions and Chronic Overuse Injuries And Injury Prevention; and Tumors and Tumor-Like Conditions. Readers will come away with the most current information on this important topic.
Author: Mikel San-Julian Publisher: Springer ISBN: 3319242202 Category : Medical Languages : en Pages : 283
Book Description
The second edition of this well-received book reflects the state of the art in surgery for malignant bone tumors in children, with a particular focus on epiphysiolysis before excision. With a thorough update, new chapters, a clear presentation of tips and tricks to address complications, as well as supplementary online videos and tutorials, this book addresses the challenges of limb preservation that are posed to the surgeon in this new era of cancer treatment characterized by higher survival rates and longer survival times. The authors are experienced practitioners of Cañadell's technique, but the book also explores, thanks to the focused contributions of experts from other fields of medicine, a range of topics from the molecular biology and histological aspects of bone tumors, to the use of imaging techniques and surgical options for epiphyseal preservation. Abundant illustrations and accounts of clinical results make this book an indispensable guide for orthopedic surgeons and pediatric oncologists and give the book an interdisciplinary appeal to practitioners in more general orthopedics, oncology, pediatrics and surgery.
Author: Carol A. Wise
Author: Carol A. Wise
Author: Ian D. Young
Author: Frederic Shapiro
Author: Frederic Shapiro
Author: 
Author: J.G. Thometz
Author: John M. Flynn
Author: John A. Herring
Author: Paul Haynes
Author: Mikel San-Julian