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Author: Lutz Hein Publisher: Springer Science & Business Media ISBN: 9783540001096 Category : Medical Languages : en Pages : 692
Book Description
Up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects.
Author: Lutz Hein Publisher: Springer Science & Business Media ISBN: 9783540001096 Category : Medical Languages : en Pages : 692
Book Description
Up-to-date information on animal models generated by transgenic or gene targeting techniques. Naturally, the focus is on the mouse system. Each chapter has been written by leading experts in the field and gives an overview on existing animal models. This is facilitated by tables, which list the most important genetically engineered animal models and their phenotypes. This book aims at illustrating the impact of transgenic animal models in the field of Experimental Pharmacology and Toxicology, which includes their role in the understanding of basic cellular mechanisms, the evaluation of potential drug targets or the testing for drug effects.
Author: Richard D. Granstein Publisher: Springer Science & Business Media ISBN: 3540359893 Category : Medical Languages : en Pages : 248
Book Description
Much anecdotal information has suggested an influence of psychology and the nervous system on immunity within the skin and the expression of inflammatory skin disorders. Recent years have seen an explosion of knowledge providing a scientific basis for important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin. The results of recent investigations have important implications, not only for an understanding of cutaneous immunity, but also for the development of novel treatments for diseases involving abnormal inflammation or immune reactivity within the skin. This book provides a comprehensive and interdisciplinary review of the molecular biology, cell biology, biochemistry and clinical aspects of nervous system–immune system interactions within the skin. It includes contributions from leading world experts in these areas. The contents are relevant to both investigators and clinicians interested in the skin, its functions and its disorders.
Author: Gerhard M. Artmann Publisher: Springer Science & Business Media ISBN: 3642118658 Category : Technology & Engineering Languages : en Pages : 566
Book Description
The potential of stem cells for healing and disease prevention in all fields of medicine is tremendous and has revolutionized the high-tech biomedical research. In this book, many of the most prominent researchers discuss the challenging topics of stem cell engineering, for example: Ethical issues of stem cell research; technological challenges, stem cell growth and differentiation, therapeutic applications, bioreactors and bioprocesses, high throughput and microfluidic screening platforms, stem cell identification and sorting, intercellular signaling and engineered niches, novel approaches for embryonic and adult stem cell growth and differentiation, stem cells and drug discovery, screening platforms. Stem Cell Engineering offers valuable background and reference for both the public and professionals including industrial staffers, faculty, researchers, engineers, students and scientific journalists.
Author: Gebhard Wagener Publisher: Springer ISBN: 3319642987 Category : Medical Languages : en Pages : 536
Book Description
Providing anesthesiology for liver surgery and especially liver transplantation is highly complex and requires profound expertise in the physiology and pathophysiology of liver disease. This new edition incorporates the latest information in the field and remains the only available book on the topic. It focuses on the practical aspect of liver anesthesiology and critical care, while providing a comprehensive and in depth summary of the knowledge in this field. Most liver transplant centers now have dedicated teams providing anesthesia care during liver transplantations. In the last years there has been a substantial increase in knowledge and improvement in techniques in anesthesiology and critical care of patients undergoing liver surgery and transplant patients. Liver Anesthesiology and Critical Care Medicine, 2nd Edition includes new chapters on chronic liver failure and hepatic cirrhosis, preoperative risk assessment, evidence in liver anesthesiology, the splanchnic and systemic circulation in liver disease and a special focus on analgesia for liver resection including regional techniques. Written for anesthesiologists and critical care physicians caring for patients undergoing liver surgery and transplantation, this book proves to be an essential companion and review book as the number of liver surgeries with higher complexity continue to increase.
Author: Dorland Publisher: Elsevier Health Sciences ISBN: 0323442544 Category : Medical Languages : en Pages : 481
Book Description
Medical acronyms and abbreviations offer convenience, but those countless shortcuts can often be confusing. Now a part of the popular Dorland's suite of products, this reference features thousands of terms from across various medical specialties. Its alphabetical arrangement makes for quick reference, and expanded coverage of symbols ensures they are easier to find. Effective communication plays an important role in all medical settings, so turn to this trusted volume for nearly any medical abbreviation you might encounter. - Symbols section makes it easier to locate unusual or seldom-used symbols. - Convenient alphabetical format allows you to find the entry you need more intuitively. - More than 90,000 entries and definitions. - Many new and updated entries including terminology in expanding specialties, such as Nursing; Physical, Occupational, and Speech Therapies; Transcription and Coding; Computer and Technical Fields. - New section on abbreviations to avoid, including Joint Commission abbreviations that are not to be used. - Incorporates updates suggested by the Institute for Safe Medication Practices (ISMP).
Author: Mauro Giacca Publisher: Springer Science & Business Media ISBN: 8847016436 Category : Medical Languages : en Pages : 318
Book Description
I entered the gene therapy field in the mid-1990s, being fascinated by the immense potential of genes as drugs for the treatment of human disease. Since then, I have experienced the ups and downs of this discipline, and tried to contribute with my work and that of my laboratory to the development of innovative approaches to the treatment of cardiovascular disorders. During these years, I have had several opp- tunities to speak on gene therapy at lectures and academic lessons, and have often noticed that the field is very attractive to scientists of all disciplines. However, as yet no comprehensive book on the subject has been published. Indeed, most books in the field are either a collection of gene transfer laboratory protocols or deal with the subject in a rather superficial manner. Hence the idea to write a gene therapy textbook that is broad and comprehensive, but at the same time provides sufficient molecular and clinical detail to be of interest to students, professors, and specialists in the various disciplines that contribute to gene therapy. I have tried to keep the language plain and, whenever possible, non-technical. Since the book is intended to be a textbook in the field of gene therapy in both the basic science and clinical areas, whenever technical descriptions are required, they are provided.
Author: A.M. Joussen Publisher: Springer Science & Business Media ISBN: 3540295410 Category : Medical Languages : en Pages : 807
Book Description
Vascular diseases of the retina are a major cause of blindness among all age groups. Edited and written by internationally well-known experts, this state-of-the-art comprehensive overview of basic and clinical science will enhance the understanding of retinal vascular disease and help in the evaluation of current and future treatment approaches for the clinician. The well-structured and highly illustrated text is divided into three easy-to-follow sections. This unique textbook-atlas also includes topics which are not currently found in other retinal disease textbooks, such as case reports and clinical follow-ups.
Author: International Society for Research on Aggression. World Meeting Publisher: Springer Science & Business Media ISBN: 9780306466243 Category : Medical Languages : en Pages : 476
Book Description
Proceedings of the XIV World Meeting of the International Society for the Research on Aggression: Prevention and Control of Aggression and the Impact on its Victims, held in July 9-14, 2000, in Valencia, Spain. Aggression is an aspect of human society that has interested scientists for many decades, and their work has provided important knowledge about its causes and way to prevent and control this behavior. However, not only scientists but many professionals working in the wide spectrum of society, from family to international policy, are interested in having programs of interventions capable of reducing aggression and violence in our society. This comprehensive book is a compendium of most research approaches that are currently taking place in the field of aggression, focusing on the interventions to control and prevent this behavior and the impact on its victims. The chapters of the book include biological approaches to aggression, such as neuroanatomy, neurochemistry, neuroendocrinology, genetics and psychopathology; information about aggression in children and adolescents in different settings such as family, school and community; characteristics if aggression in specific relationships such as marital and sexual, and specific settings such as bars, prisons and traffic; and cultural approaches to aggression, social prejudice, war and programs of peace. Furthermore, a small number of representative chapters about victims are included, ranging from the impact of aggression on behavior and physiology in animal models to victims of war. As this book highlights, the interventions to prevent and control aggression have to be diverse (highly heterogenic) in order to deal with all aspects of human beings and society, ranging from pharmacological control in individuals to programs of peace to promote respect among people and among nations. Scientists, academics and professionals dealing with any facet of aggression and its impact on our society will obtain in this book information about the complexity of this research field and the ways to approach our objective: eliminate aggression from the human behavioral repertoire.
Author: Jens F. Rehfeld Publisher: Springer Science & Business Media ISBN: 3642118364 Category : Science Languages : en Pages : 245
Book Description
The concept of hormonal regulation using intercellular peptide messengers dates back to the discovery of secretin in 1902. The concept was simple: A peptide is released from specific hormone producing cells, endocrine cells, into circulation upon stimulation of the cells. The peptide hormone travels via blood to its target, the cells of which are equipped with specific receptors for high-affinity binding of the particular peptide hormone. Receptor binding subsequently elicits action of the target cells. This concept has been seriously challenged by modern biochemistry and cell biology. Thus, it is now well established that the gene of a specific peptide hormone may be expressed in different types of endocrine cells, in neurons, and in some instances also in adipocytes, myocytes, osteoblasts, and immune cells. Today, only a few hormones – including the old master hormone insulin – represent the original endocrine paradigm. Instead, the widespread cellular synthesis now raises the qu- tion of how the body maintains the regulation of its functions by peptide hormones when a hormone may originate from a variety of cells.
Author: Lutz Hein
Author: Lutz Hein
Author: Richard D. Granstein
Author: Gerhard M. Artmann
Author: Gebhard Wagener
Author: Dorland
Author: Mauro Giacca
Author: A.M. Joussen
Author: Sean Kehoe
Author: International Society for Research on Aggression. World Meeting
Author: Jens F. Rehfeld