Author: Emel ArinçPublisher: Springer Science & Business Media
ISBN: 1468472844
Category : Medical
Languages : en
Pages : 493
Book Description
Proceedings of a NATO ASI held in Çesme (Izmir), Turkey, August 27-September 7, 1989.
Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds
Author: Emel ArinçPublisher: Springer Science & Business Media
ISBN: 1468472844
Category : Medical
Languages : en
Pages : 493
Book Description
Proceedings of a NATO ASI held in Çesme (Izmir), Turkey, August 27-September 7, 1989.
Molecular Aspects of Oxidative Drug Metabolizing Enzymes
Author: Emel ArincPublisher: Springer Science & Business Media
ISBN: 3642795285
Category : Science
Languages : en
Pages : 615
Book Description
Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of genetically engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity.
National Library of Medicine Current Catalog
Author: National Library of Medicine (U.S.)Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1332
Book Description
Molecular, Clinical and Environmental Toxicology
Author: Andreas LuchPublisher: Springer Science & Business Media
ISBN: 3764383364
Category : Medical
Languages : en
Pages : 479
Book Description
Molecular Toxicology is the first volume of a three-volume set Molecular, Clinical and Environmental Toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals in daily life. By providing intriguing insights far down to the molecular level, this work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health and engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.
Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes
Author: Emel ArinçPublisher: Springer Science & Business Media
ISBN: 1461548551
Category : Science
Languages : en
Pages : 297
Book Description
Proceedings of a NATO ASI held in Antalya, Turkey, August 31 - September 11, 1997
Current Catalog
Author: National Library of Medicine (U.S.)Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 690
Book Description
First multi-year cumulation covers six years: 1965-70.
Cytochrome P450
Author: John B. SchenkmanPublisher: Springer Science & Business Media
ISBN: 3642777635
Category : Medical
Languages : en
Pages : 740
Book Description
The most complete and up-to-date survey of this important superfamily of enzymes, including the first ever coverage of the forms involved in steroid hormone biosynthesis. The components of the enzyme system, the reaction mechanisms involved, and the evolution and nomenclature are analyzed, as is the hepatic microsomal enzyme in a large number of species, illustrating the very wide implications for life processes.
Introduction to Drug Metabolism
Author: G. GORDON GIBSON AND PAUL SKETTPublisher: Springer
ISBN: 148996844X
Category : Medical
Languages : en
Pages : 275
Book Description
This introduction to the mechanisms by which the body metabolizes and excretes administered drugs is directed at advanced undergraduate biochemists, pharmacologists, pre-clinical medical students and advanced undergraduate/postgraduate toxicologists.
Environmental Health Perspectives
Author: Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 754
Book Description
Cell Culture Methods for In Vitro Toxicology
Author: G. StaceyPublisher: Springer Science & Business Media
ISBN: 9401709963
Category : Medical
Languages : en
Pages : 166
Book Description
Cell Culture Methods for in vitro Toxicology introduces the reader to a range of techniques involved in the use of in vitro cell culture in toxicological studies. It deals with major cell types studied in the field of toxicology and will be useful for anyone wishing to start work with animal cell cultures or to refresh their knowledge relating to in vitro cell models. Fundamental chapters deal with the general biology of cytotoxicity and cell immortalisation these are key issues for in vitro systems addressing the `3Rs' principle. Up-to-date overviews deal with the use of cells from liver, brain and intestine. In addition, biochemical analysis of cell responses, biotransformation pathways in cells and recombinant approaches to the early detection of cell stress are also covered in detail. Prominent features of in vitro technologies also include regulation, biosafety and standardisation. Dedicated chapters deal with these issues in a practical way in order to lead the reader to the right source of information. This book provides an up-to-date, informative and practical review of cell culture methods for in vitro toxicology. It will be of equal benefit to students and experienced toxicologists with little experience of in vitro cell culture.