Author: Eric D. SchwoebelPublisher:
ISBN:
Category : Zona pellucida
Languages : en
Pages : 246
Book Description
Molecular Analysis of the CDNA Encoding the 55-kDa Rabbit Zona Pellucida Protein
Author: Eric D. SchwoebelPublisher:
ISBN:
Category : Zona pellucida
Languages : en
Pages : 246
Book Description
Reproductive Immunology
Author: Satish Kumar GuptaPublisher: Springer Science & Business Media
ISBN: 9401141975
Category : Medical
Languages : en
Pages : 416
Book Description
Reproductive Immunology is a compilation of research articles presented during the VII International Congress of Reproductive Immunology which was held in New Delhi, India on 27-30 October 1998. The articles pertain to the following six major themes: Molecular and Immunological Aspects of Sperm-Egg Interaction Embryonic-Endometrial Cross-Talk Immunobiology of Pregnancy Autoantibodies and Infertility Immunocontraception Mucosal Immunology and Reproductive Tract Infections . The first section deals with our current understanding of various steps involved in fertilization. The functional significance of sperm surface mannosidase and glutathione S-transferases to bind zona pellucida is described. The role of zona pellucida glycoproteins in the binding of sperm, induction of acrosome reactions and avoidance of polyspermy is discussed. In the second section, the role of various cytokines, growth factors and immunomodulatory agents in implantation of embryos is described. In the field of reproductive immunology, one of the major issues is to explore the successful gestation of the histoincompatible fetus in the uterus of an immunologically competent mother. The Proceedings presents the issues of paternal antigens at the feto-maternal interface and shows that Th2-type of immunity is involved in normal successful conception. The role of membrane-bound and soluble HLA-G in protecting the fetus from the lytic activities of maternal uterine and peripheral blood natural killer (NK) cells is also presented. Nature's experiments suggest that antibodies against sperm-specific antigens are responsible for infertility in some women. The possibility that an immunogenetic background contributes to production of sperm-immobilizing antibodies in infertile women is discussed in the section on autoantibodies and infertility. The Proceedings presents the issue of Th1-type cytokines in inducing recurrent spontaneous abortions of unexplained etiology. The roles of β2-glycoprotein 1 (β2-GP1)-dependent anticardiolipin antibody, lupus anticoagulant, antiphospholipids, anti-thyroid antibody and anti-nuclear antibody in miscarriages are also described. The rising global human population, particularly in the developing countries, has driven the need for new and safer methods of contraception. Fertility regulation by vaccines is thus an interesting proposition. The section on contraceptive vaccines discusses the latest advances in this area and describes the current status of vaccines based on βhCG, sperm antigens, zona pellucida glycoproteins, and riboflavin carrier proteins. The issues of mucosal immunity and strategies for enhancing local genital immune responses to combat HIV infection is discussed. The role of inflammatory and related cytokines in chorioamnionitis is described. The contents of this Proceedings describes various facets of reproductive immunology which will help us to design strategies to combat genital infections and miscarriages caused by immunological etiology. Descriptions of the molecular basis of gamete recognition, implantation and survival of the allogenic fetus will help in designing strategies for overcoming infertility and also new contraceptive approaches. The Proceedings will be useful to researchers and clinicians involved in basic or applied research in the disciplines of reproductive biology, reproductive immunology, and obstetrics and gynecology.
Zona Pellucida Glycoproteins and Immunocontraception
Author: S. K. GuptaPublisher:
ISBN:
Category : Contraception, Immunological
Languages : en
Pages : 216
Book Description
Contains the proceeds of the International Symposium on Prospects of Zona Pellucida Glycoproteins for Immunocontraception held in New Delhi in 1995. The text provides a critical appraisal of the potential of zona pellucida glycoprotiens in the design of a fertility regulating vaccine.
Fertilization
Author: Daniel M. HardyPublisher: Academic Press
ISBN: 9780123116291
Category : Medical
Languages : en
Pages : 456
Book Description
Gamete reansport / Susan S. Suarez -- Sperm motility activation and chemoattraction / Timothy A. Quill and David L. Garbers -- Capacitation / Bijay S. Jaiswal and Michael Eisenbach -- Function of the egg's extracellular matrix / Richard A. Cardullo and Catherine D. Thaler -- Sperm adhesion to the extracellular / Ming Bi, Michael J. Wassler, and Daniel M. Hardy -- Signal transduction mechanisms regulating sperm acrosomal exocytosis / Gregory S. Kopf -- Regulation of sperm ion currents / Alberto Darszon, Felipe Espinosa, Blanca Galindo, Daniel Sánchez, and Carmen Beltrán -- Function of the sperm acrosome/ George L. Gerton -- Gamete fusion in mammals / Paul Primakoff and Diana G. Myles -- Membrane events of egg activation / Karl Swann and Keith T. Jones -- Molecular genetics of fertilization / Patricia Olds-Clarke and Stephen H. Pilder -- Gemete immunobiology / M.G. O'rand and I.A. Lea -- Fertilization biophysics / D.P.L. Green -- Applications of fertility regulation for the management of ...
Cumulated Index Medicus
Author: Cambridge Scientific Biochemistry Abstracts
Author: Proceedings
Author: Indian National Science AcademyPublisher:
ISBN:
Category : Biology
Languages : en
Pages : 664
Book Description
Journal of Reproduction and Fertility
Author: Publisher:
ISBN:
Category : Fertility
Languages : en
Pages : 688
Book Description
Includes the Proceedings of the Society for the Study of Fertility.
Nucleic Acids Abstracts
Author: Proceedings of the Indian National Science Academy
Author: Indian National Science AcademyPublisher:
ISBN:
Category : Biology
Languages : en
Pages : 662
Book Description