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Genetic Control of Malaria and Dengue

Genetic Control of Malaria and Dengue PDF Author: Zach N. Adelman
Publisher: Academic Press
ISBN: 0128004053
Category : Medical
Languages : en
Pages : 487

Book Description
Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. - Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission - Provides a summary of the concepts of both population suppression and population replacement - Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies

Genetic Control of Malaria and Dengue

Genetic Control of Malaria and Dengue PDF Author: Zach N. Adelman
Publisher: Academic Press
ISBN: 0128004053
Category : Medical
Languages : en
Pages : 487

Book Description
Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown. - Includes coverage of vectorial capacity, critical to understanding vector-borne disease transmission - Provides a summary of the concepts of both population suppression and population replacement - Contains pivotal coverage of ethical and ecological ramifications of genetics-based control strategies

Sex Determination and Sexual Development

Sex Determination and Sexual Development PDF Author:
Publisher: Academic Press
ISBN: 0080922848
Category : Science
Languages : en
Pages : 306

Book Description
This volume reviews our current understanding for how sex determination is initiated and how it results in sexual dimorphic development. Chapters discussing work on different model systems provide a basis for understanding similarities that exist between different species. Coverage includes discussion of sexual development of the soma in C. elegans; sexual development of the germline in C. elegans; sexual development of the soma in Drosophila; sexual development of the germline in Drosophila; sexual development of the soma in the mouse; sexual development of the germline in the mouse; control of sex-specific behavior in Drosophila; and control of sex-specific behavior in vertebrates. - Uncovers the latest research findings on sexual determination and sexual development - Model systems illustrate key sexual similarities - Explores in-depth the origins of sex specific behavior

Molecular Analysis of Tra-2

Molecular Analysis of Tra-2 PDF Author: Peter Gerald Okkema
Publisher:
ISBN:
Category :
Languages : en
Pages : 356

Book Description


Molecular Approaches to Fundamental and Applied Entomology

Molecular Approaches to Fundamental and Applied Entomology PDF Author: John Oakeshott
Publisher: Springer Science & Business Media
ISBN: 1461392179
Category : Science
Languages : en
Pages : 513

Book Description
Insects as a group occupy a middle ground in the biosphere between bacteria and viruses at one extreme, amphibians and mammals at the other. The size and general nature of insects present special problems to the study of entomology. For example, many commercially available instruments are geared to measure in grams, while the forces commonly encountered in studying insects are in the milligram range. Therefore, techniques developed in the study of insects or in those fields concerned with the control of insect pests are often unique. Methods for measuring things are common to all sciences. Advances sometimes depend more on how something was done than on what was measured; indeed a given field often progresses from one technique to another as new methods are discovered, developed, and modified. Just as often, some of these techniques find their way into the classroom when the problems involved have been sufficiently ironed out to permit students to master the manipulations in a few laboratory periods. Many specialized techniques are confined to one specific research laboratory. Although methods may be considered commonplace where they are used, in another context even the simplest procedures may save considerable time. It is the purpose of this series (1) to report new developments in methodology, (2) to reveal sources of groups who have dealt with and solved particular entomological problems, and (3) to describe experiments which may be applicable for use in biology laboratory courses.

The Origin and Evolution of Sex

The Origin and Evolution of Sex PDF Author: Harlyn O. Halvorson
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 368

Book Description


Genetic and Molecular Analysis of Suppressors of the Drosophila Melanogaster Female-specific Lethal Mutation SisterlessA1

Genetic and Molecular Analysis of Suppressors of the Drosophila Melanogaster Female-specific Lethal Mutation SisterlessA1 PDF Author: Daniel Alan Barbash
Publisher:
ISBN:
Category :
Languages : en
Pages : 520

Book Description


Reproductive Biology of Invertebrates, Vol. 12, Part B

Reproductive Biology of Invertebrates, Vol. 12, Part B PDF Author: A S Raikhel
Publisher: CRC Press
ISBN: 1482280108
Category : Science
Languages : en
Pages : 427

Book Description
This book discusses the major accomplishments made in elucidating vitellogenic events at the cellular, biochemical, and molecular biological levels. It is helpful for researchers and students interested in reproduction of invertebrates.

Molecular Genetics of Sex Determination

Molecular Genetics of Sex Determination PDF Author: Stephen S. Wachtel
Publisher: Academic Press
ISBN: 1483295583
Category : Science
Languages : en
Pages : 537

Book Description
In this era of accelerated discovery and prolific output, Molecular Genetics of Sex Determination keeps readers abreast of this fields fast-moving biology. Its chapters were completed by experts in eacharea only months before publication. The text is organized into two parts. First, it reviews the basic biology of sex determination and summarizes ground-breaking work in mouse, marsupial, and Drosophila systems. Second, it covers current human genetics, clinical studies, and the syndromes of abnormal sex differentiation. With chapters by preeminent reproductive biologists, this is a capital work. Ohno's law is described by Ohno; the Lyon hypothesis, by Lyon; Sinclair tells how he cloned the testis-determining gene; and so on. Molecular Genetics of Sex Determination is authoritative, comprehensive, and current. It is prime reading for geneticists, developmental biologists, graduate students in these and related fields, clinical researchers, physicians, and medical students. - Reviews the genetics of sex determination in 19 up-to-date chapters - Features research on sex chromosomes and sex-determining genes - Includes abnormalities of sex determination and clinical genetics - Written by scientists who pioneered work in this field

Research Awards Index

Research Awards Index PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 776

Book Description


RNA: Catalysis, Splicing, Evolution

RNA: Catalysis, Splicing, Evolution PDF Author: M. Belfort
Publisher: Elsevier
ISBN: 0444599711
Category : Science
Languages : en
Pages : 239

Book Description
The conference on "RNA: Catalysis, Splicing, Evolution" brought together a unique assembly of scientific leaders in this currently very important field. Two participants of this Conference, Drs. T.R. Cech and S. Altman, were just awarded the 1989 Nobel prize in chemistry, which attests to the timeliness of this volume. The critical reviews authored by these two prominent scientists are included. For those scientists with roots in this field, who do not subscribe to GENE, this is an excellent opportunity to obtain a masterly collection of papers. All the original papers and reviews have undergone the rigorous peer review of the journal "Gene".