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Handbook of Models for Human Aging

Handbook of Models for Human Aging PDF Author: P. Michael Conn
Publisher: Elsevier
ISBN: 0080460062
Category : Medical
Languages : en
Pages : 1103

Book Description
The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. - Utilizes a multidisciplinary approach - Shows tricks and approaches not available in primary publications - First volume of its kind to combine both methods of study for human aging and animal models - Over 200 illustrations

Handbook of Models for Human Aging

Handbook of Models for Human Aging PDF Author: P. Michael Conn
Publisher: Elsevier
ISBN: 0080460062
Category : Medical
Languages : en
Pages : 1103

Book Description
The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. - Utilizes a multidisciplinary approach - Shows tricks and approaches not available in primary publications - First volume of its kind to combine both methods of study for human aging and animal models - Over 200 illustrations

Exceptional Longevity

Exceptional Longevity PDF Author: Bernard Jeune
Publisher:
ISBN:
Category : Health & Fitness
Languages : en
Pages : 180

Book Description
States that the number of genuine long-livers is exploding and a substantial proportion of new-borns in developed countries may survive to celebrate their 100th birthday. This book examines the storied realms of exceptional longevity.

Model Ecosystems in Extreme Environments

Model Ecosystems in Extreme Environments PDF Author:
Publisher: Academic Press
ISBN: 0128127430
Category : Science
Languages : en
Pages : 230

Book Description
Model Ecosystems in Extreme Environments, Second Edition examines ecosystems at the most extreme habitats and their interaction with the environment, providing a key element in our understanding of the role and function of microorganisms in nature. The book highlights current topics in the field, such as biodiversity and the structure of microbial communities in extreme environments, the effects of extreme environmental conditions on microbial ecosystems, and ecological and evolutionary interactions in extreme environments, among other topics. It will be a valuable text for faculty and students working with extremophiles and/or microbial ecology and researchers, including astrobiologists, biologists, evolutionary scientists, astronomers, geochemists and oceanographers. - Explores, in detail, how microbial ecosystems thrive in extreme environments - Highlights the relevance of extremophiles as model ecosystems to the study of microbial ecology - Examines how extreme ecosystems can help our search for life on other planets

Papers of the Conference on Genetics of Aging and Longevity 2012

Papers of the Conference on Genetics of Aging and Longevity 2012 PDF Author: Alexey Moskalev
Publisher: Frontiers E-books
ISBN: 2889193535
Category : Genetics
Languages : en
Pages : 141

Book Description


Extreme Value Theory

Extreme Value Theory PDF Author: Laurens de Haan
Publisher: Springer Science & Business Media
ISBN: 0387344713
Category : Mathematics
Languages : en
Pages : 421

Book Description
Focuses on theoretical results along with applications All the main topics covering the heart of the subject are introduced to the reader in a systematic fashion Concentration is on the probabilistic and statistical aspects of extreme values Excellent introduction to extreme value theory at the graduate level, requiring only some mathematical maturity

Development of the Rodent as a Model System of Aging

Development of the Rodent as a Model System of Aging PDF Author: Don C. Gibson
Publisher:
ISBN:
Category : Aging
Languages : en
Pages : 334

Book Description


Centenarians—A Model to Study the Molecular Basis of Lifespan and Healthspan

Centenarians—A Model to Study the Molecular Basis of Lifespan and Healthspan PDF Author: Annibale Puca
Publisher: MDPI
ISBN: 3036509801
Category : Science
Languages : en
Pages : 204

Book Description
People around the world are living longer. For the first time in history, most humans will live to be sixty and beyond. By 2050, the world's population aged 60 and over will reach a total of 2 billion, up from 900 million in 2015. Today, 125 million people are 80 years of age or older. By 2050, there will be 434 million people in this age group worldwide. In addition, the pace of aging of the world population is also increasing. However, there is not enough evidence to show that older people have better health than their parents. While rates of severe disability have declined over the past 30 years (but only in high-income countries), there have been no significant changes in mild to moderate disability over the same period of time. Indeed, the increase in the duration of life (lifespan) does not coincide with the increase in the duration of health (healthspan), that is, the period of life free from serious chronic diseases and disabilities. Therefore, the identification of the factors that predispose to a long and healthy life, as discussed in the papers of this book, is of enormous interest for translational medicine.

Advances in Theoretical and Applied Statistics

Advances in Theoretical and Applied Statistics PDF Author: Nicola Torelli
Publisher: Springer Science & Business Media
ISBN: 3642355889
Category : Mathematics
Languages : en
Pages : 538

Book Description
This volume includes contributions selected after a double blind review process and presented as a preliminary version at the 45th Meeting of the Italian Statistical Society. The papers provide significant and innovative original contributions and cover a broad range of topics including: statistical theory; methods for time series and spatial data; statistical modeling and data analysis; survey methodology and official statistics; analysis of social, demographic and health data; and economic statistics and econometrics.

The Albergo Diffuso Model

The Albergo Diffuso Model PDF Author: Maurizio Droli
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110643766
Category : Business & Economics
Languages : en
Pages : 248

Book Description
The hospitality model called "Albergo Diffuso" (AD), or "scattered hotel," has been engneered by Mr Giancarlo Dall'Ara and described by The New York Times as a way of bringing life back to historic towns and rural hamlets by utilizing unused rooms for tourism. This "simple but genial" model devised in Italy in the mid-90's received an award from the UNDP for its sustainability, but despite the spread of AD's, no peer-reviewed books have previously been published in English focusing on this innovation. In this book, the author therefore begins by exploring the AD as a community-based hospitality model, examining both its pros and cons. He then considers conviviality, sense of security, and other factors that Hans Magnus Enzensberger referred to as luxuries of our time for urban dwellers. These represent the key pre-requisites a location must possess to be deemed suitable for this innovation. Next, investors and co-interested private, public and not-for-profit associations are provided with a structured framework to help them achieve a defensible competitive advantage by harnessing the economic potential of valuable, rare, inimitable and non-substitutable (VRIN) resources. The final section assesses the AD as a business model, evaluating various aspects at the heart of any business plan.

Longevity

Longevity PDF Author: James R. Carey
Publisher: Princeton University Press
ISBN: 0691224080
Category : Science
Languages : en
Pages : 305

Book Description
Despite our deep interest in mortality, little is known about why some individuals live to middle age and others to extreme old age. Life span, mortality, and aging present some of the most profound mysteries in biology. In Longevity, James Carey draws on unprecedented data to develop a biological and demographic framework for identifying the key factors that govern aging, life span, and mortality in humans and other animals. Carey presents the results of a monumental, twelve-year, National Institute on Aging-funded research project on the determinants of longevity using data from the life tables of five million Mediterranean fruit flies, the most comprehensive set of life table studies ever on the mortality dynamics of a single species. He interprets the fruit fly data within the context of human aging and the aging process in general to identify the determinants of mortality. Three key themes emerge: the absence of species-specific life span limits, the context-specific nature of the mortality rate, and biodemographic linkages between longevity and reproduction. A powerful foundation for the emerging field of biodemography and a rich framework for considering the future of human life span, Longevity will be an indispensable resource for readers from a range of fields including population biology, demography, gerontology, ecology, evolutionary biology, and medical research.