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Author: Richard Bucala Publisher: Springer ISBN: 3319523546 Category : Science Languages : en Pages : 247
Book Description
The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, metabolism, and cellular stress responses. MIF’s molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. New family members, such as D-dopachrome tautomerase, or MIF-2, and the closely homologous genes encoding by parasites have been defined and are being functionally characterized. MIF directed therapies also are entering clinical testing and ultimately may be applied in a pharmacogenomics manner. This book provides a comprehensive synthesis of the state-of-the-art of MIF science. The intended audience are post-graduate students and researchers in inflammation, innate immunity, immunology, and immunopathology.
Author: Richard Bucala Publisher: Springer ISBN: 3319523546 Category : Science Languages : en Pages : 247
Book Description
The role of the cytokine macrophage migration inhibitory factor (MIF) in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well-established. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, metabolism, and cellular stress responses. MIF’s molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. New family members, such as D-dopachrome tautomerase, or MIF-2, and the closely homologous genes encoding by parasites have been defined and are being functionally characterized. MIF directed therapies also are entering clinical testing and ultimately may be applied in a pharmacogenomics manner. This book provides a comprehensive synthesis of the state-of-the-art of MIF science. The intended audience are post-graduate students and researchers in inflammation, innate immunity, immunology, and immunopathology.
Author: Faith H. A. Osier Publisher: Frontiers Media SA ISBN: 288963874X Category : Languages : en Pages : 187
Book Description
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Author: National Research Council Publisher: National Academies Press ISBN: 0309180686 Category : Medical Languages : en Pages : 102
Book Description
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Author: Ian McConachie Publisher: Cambridge University Press ISBN: 0521678579 Category : Medical Languages : en Pages : 453
Book Description
Handbook of ICU Therapy provides rapid access to important information on the treatment of the critically ill patient. It comprises a series of 'cutting edge' reviews of the most advanced treatment concepts available in the modern ICU. Whilst assuming a basic knowledge of underlying conditions, it nonetheless outlines key physiological principles where necessary, and critically reviews current literature and best practice. The heart of the book is aimed at providing key practical information on treatment techniques to the busy clinician in an easily accessible style. In addition to conventional drug therapy, ventilator, fluid and physical therapies are also discussed in detail. All of the authors are directly involved in ICU research and practice and are familiar with all of the latest developments in this fast-moving field of medicine.
Author: Diana Boraschi Publisher: Frontiers Media SA ISBN: 2832544347 Category : Medical Languages : en Pages : 848
Book Description
We are delighted to present the inaugural Frontiers in Immunology “Women in Cytokines and Soluble Mediators in Immunity” series of article collections. At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and Science, Technology, Engineering and Mathematics (STEM) research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.
Author: Katherine A. Fitzgerald Publisher: Elsevier ISBN: 0080530206 Category : Medical Languages : en Pages : 526
Book Description
Completely revised and expanded, this second edition of The Cytokine FactsBook is the most up-to-date reference manual available for all current well-characterized interleukins, cytokines, and their receptors. An additional 52 cytokines are included, doubling the number of entries from the previous edition. The key properties of each cytokine are described and presented in a very accessible format with diagrams for each of the receptors. The Cytokine FactsBook includes free online access to the regularly updated Cytokine Webfacts. Cytokine Webfacts is a web-based comprehensive compendium of facts about cytokines and their receptors that includes a variety of data representations, such as text, signal pathway diagrams and 3D images. This exciting resource is integrated into other databases via hypertext links to provide a unique network, and contains a web-enabled version of RasMol for viewing structures.
Author: Jean L. Bolognia Publisher: Elsevier Health Sciences ISBN: 0702084697 Category : Medical Languages : en Pages : 3312
Book Description
**Selected for Doody's Core Titles® 2024 in Dermatology**For dermatology residents and trainees, as well as those in clinical practice, Dermatology is the leading reference for understanding, diagnosing, and treating the full spectrum of skin disease—and is the key resource that residents rely on throughout their training and certification. Widely recognized for its easy-in, easy-out approach, this revised 5th Edition turns complex information into user-friendly visual content through the use of clear, templated chapters, digestible artwork, and easy-to-follow algorithms and tables. This two-volume masterwork provides complete, authoritative coverage of basic science, clinical practice of both adult and pediatric dermatology, dermatopathology, and dermatologic surgery—more than any other source, making it the gold standard reference in the field today. - Simplifies complex content in a highly accessible, highly visual manner, with 1,100+ tables; 2,600+ figures, including numerous disease classification algorithms as well as diagnostic and therapeutic pathways; and over 1,500 additional figures and tables online. - Utilizes weighted differential diagnosis tables and a "ladder" approach to therapeutic interventions. - Any additional digital ancillary content may publish up to 6 weeks following the publication date. - Features an intuitive organization and color-coded sections that allow for easy and rapid access to the information you need. - Retains an emphasis on clinicopathologic correlations, with photomicrographs demonstrating key histologic findings adjacent to clinical images of the same disorder. - Contains updated treatment information throughout, including immune checkpoint inhibitors, JAK inhibitors, and monoclonal antibodies for a wide range of conditions such as psoriasis, atopic dermatitis, alopecia areata, vitiligo, and skin cancers. - Provides up-to-date information on genetic and molecular markers and next-generation sequencing as it applies to dermatologists. - Features new videos, including cryosurgical and suturing techniques, treatment of rhinophyma via electrosection, and neuromodulator treatment of axillary hyperhidrosis. - Includes new WHO classifications of skin tumors, new FDA pregnancy drug labeling, and new ACR/EULAR criteria for vasculitis and lupus erythematosus. - Includes new sections on confocal microscopy and artificial intelligence.
Author: Peter J. Barnes Publisher: Elsevier ISBN: 0080920608 Category : Medical Languages : en Pages : 897
Book Description
The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations
Author: Jean L. Bolognia Publisher: Elsevier Health Sciences ISBN: 0702063428 Category : Medical Languages : en Pages : 2752
Book Description
With more complete, authoritative coverage of basic science, clinical practice of both adult and pediatric dermatology, dermatopathology, and dermatologic surgery than you'll find in any other source, Dermatology, 4th Edition, is the gold-standard reference in the field today. Drs. Jean L. Bolognia, Julie V. Schaffer, and Lorenzo Cerroni bring their considerable knowledge and experience to this two-volume masterwork, ensuring its reliability and usefulness for both residents and practitioners. Provides the in-depth, expert information you need to address challenges you face in practice across all subspecialties – including medical dermatology, pediatric dermatology, dermatopathology, dermatologic surgery, and cosmetic dermatology. Uses the famous "easy-in, easy-out" approach, transforming complex information into more than 1,000 reader-friendly tables and algorithms, along with templated chapter contents for quick recognition and access. Focuses on the essential "need-to-know" basic science information and key references. Brings together an esteemed team of expert editors and contributors that provide a truly global perspective, led by Drs. Jean L. Bolognia, Julie V. Schaffer, and Lorenzo Cerroni. Includes over 4,000 illustrations, with over 2,000 new images in this edition, that provide more examples of skin disorders across different skin types in varying stages of presentation; plus enhanced histologic images that provide a clearer understanding of clinicopathologic correlations for multiple skin disorders. Features 70 brand-new schematics and algorithms to better aid diagnosis, optimize decision making, and improve your approach to each patient. Includes the latest therapy options with supporting evidence-based grading levels.
Author: Richard Bucala
Author: Richard Bucala
Author: Faith H. A. Osier
Author: National Research Council
Author: Ian McConachie
Author: Diana Boraschi
Author: Dunfang Zhang
Author: Katherine A. Fitzgerald
Author: Jean L. Bolognia
Author: Peter J. Barnes
Author: Jean L. Bolognia