Author: F. GrussuPublisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Microstructural Imaging of the Human Spinal Cord with Advanced Diffusion MRI.
Author: F. GrussuMicrostructural Imaging of the Human Spinal Cord with Advanced Diffusion MRI
Author: Francesco GrussuQuantitative MRI of the Spinal Cord
Author: Julien Cohen-AdadPublisher: Academic Press
ISBN: 0123972825
Category : Medical
Languages : en
Pages : 331
Book Description
Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory’s applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord. Chapters authored by international experts in the field of MRI of the spinal cord Contains “cooking recipes —examples of imaging parameters for each quantitative technique—designed to aid researchers and clinicians in using them in practice Ideal for clinical settings
Diffusion Magnetic Resonance Imaging of the Human Spinal Cord in Vivo
Author: Samantha ByPublisher:
ISBN:
Category : Electronic dissertations
Languages : en
Pages : 126
Book Description
Microstructure Imaging in the Human Brain with Advanced Diffusion MRI and Machine Learning
Author: Noémi G. GyőriDiffusion MRI
Author: Heidi Johansen-BergPublisher: Academic Press
ISBN: 0124055095
Category : Medical
Languages : en
Pages : 627
Book Description
Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie. Fully revised and updated edition of the first comprehensive reference on a powerful technique in brain imaging Covers all aspects of a diffusion MRI study from acquisition through analysis to interpretation, and from fundamental theory to cutting-edge developments New chapters covering connectomics, advanced diffusion acquisition, artifact removal, and applications to the neonatal brain Provides practical advice on running an experiment Includes discussion of applications in psychiatry, neurology, neurosurgery, and basic neuroscience Full color throughout
Structural, Microstructural, and Functional Magnetic Resonance Imaging Measures of the Brain and Spinal Cord are Associated with Neurological Symptoms and Chronic Pain in Patients with Cervical Stenosis
Author: Davis C WoodworthPublisher:
ISBN:
Category :
Languages : en
Pages : 280
Book Description
Cervical stenosis (CS), or tightening of the spinal canal, that causes long-term neurological impairment including neck pain and motor weakness, is termed cervical spondylotic myelopathy (CSM). However, substantial compression of the spinal cord does not necessarily entail more severe symptomatology and evaluations of clinical magnetic resonance imaging (MRI) scans are only weakly associated with patient symptom severity and have shown limited value in predicting patient disease progression or response to treatment. Thus, non-invasive imaging biomarkers that better reflect patient symptoms are in great need. While the spinal cord is the primary site of injury in CSM, the brain can also present with degenerative or compensatory changes in relation to patient symptoms. The purpose of this dissertation was to evaluate, via advanced MRI scans, the associations between structure, function, and microstructure, of the spinal cord and brain, with neurological symptoms and pain severity in patients with CS. High-resolution structural, resting-state functional, and diffusion MRI scans of the brain and spinal cord were acquired in 26 CS patients and 17 healthy control subjects. Measures of brain and spinal cord structure, functional connectivity, and microstrucutre, were compared to the modified Japanese Orthopedic (mJOA) and the Neck Disability Index (NDI) scores. Similar to previous findings, structural measures of the spinal cord were not associated with symptom severity. However, patients with CS presented decreased brain structure with worsening neurological symptoms in subregions of the primary sensorimotor cortex, the superior frontal gyrus, and precuneus, and in the anterior cingulate and putamen in relation to both neurological and pain symptoms. These regions also demonstrated altered functional connectivity, presenting mostly with increasing connectivity with worsening symptoms. Diffusion MRI revealed altered microstructure consistent with degenerative changes in the spinal cord, both at the site of injury and at uncompressed sites, and further rostrally in the corticospinal tracts in the brain. This cross-sectional study brings the brain and spinal cord together using advanced MRI to paint a more holistic picture of patients with CSM, and provides a groundwork for future studies to evaluate the brain and spinal cord longitudinally and after surgery to help determine optimal treatment strategies.
Brain Network Analysis
Author: Moo K. ChungPublisher: Cambridge University Press
ISBN: 110718486X
Category : Computers
Languages : en
Pages : 343
Book Description
This coherent mathematical and statistical approach aimed at graduate students incorporates regression and topology as well as graph theory.
Magnetic Resonance Imaging of the Brain and Spine
Author: Scott W. AtlasPublisher: Lippincott Williams & Wilkins
ISBN: 9780781769853
Category : Medical
Languages : en
Pages : 1976
Book Description
Established as the leading textbook on imaging diagnosis of brain and spine disorders, Magnetic Resonance Imaging of the Brain and Spine is now in its Fourth Edition. This thoroughly updated two-volume reference delivers cutting-edge information on nearly every aspect of clinical neuroradiology. Expert neuroradiologists, innovative renowned MRI physicists, and experienced leading clinical neurospecialists from all over the world show how to generate state-of-the-art images and define diagnoses from crucial clinical/pathologic MR imaging correlations for neurologic, neurosurgical, and psychiatric diseases spanning fetal CNS anomalies to disorders of the aging brain. Highlights of this edition include over 6,800 images of remarkable quality, more color images, and new information using advanced techniques, including perfusion and diffusion MRI and functional MRI. A companion Website will offer the fully searchable text and an image bank.
Diffusion-Weighted MR Imaging of the Brain, Head and Neck, and Spine
Author: Toshio MoritaniPublisher: Springer Nature
ISBN: 3030621200
Category : Medical
Languages : en
Pages : 928
Book Description
This richly illustrated book, now in an updated and extended third edition, systematically covers the use of diffusion-weighted (DW) MR imaging in all major areas of neuroradiology, including imaging of the head and neck and the spine as well as the brain. The authors guide the reader from the basic principles of DW imaging through to the use of cutting-edge diffusion sequences such as diffusion tensor (DTI) and kurtosis (DKI), fiber tractography, high b value, intravoxel incoherent motion (IVIM), neurite orientation dispersion and density imaging (NODDI), and oscillating gradient spin echo (OGSE). Pathology, pathophysiology, and patient management and treatment are all thoroughly discussed. Since the early descriptions by LeBihan and colleagues of the ability to image and measure the micromovement of water molecules in the brain, diffusion imaging and its derivatives have contributed ever more significantly to the evaluation of multiple disease processes. In comprehensively describing the state of the art in the field, this book will be of high value not only for those who deal routinely with neuro-MR imaging but also for readers who wish to establish a sound basis for understanding diffusion images in the hope of extending these principles into more exotic areas of neuroimaging.