Microencapsulación de nanopartículas de quitosano para la administración pulmonar de macromoléculas terapéuticas. PDF Download

Author:
Publisher: Univ Santiago de Compostela
ISBN:
Category :
Languages : en
Pages : 307

View

Book Description

Author: Maria Jose Alonso
Publisher: Royal Society of Chemistry
ISBN: 1849733635
Category : Medical
Languages : en
Pages : 643

View

Book Description
This book provides a critical overview of the advances being made toward overcoming biological barriers through the contribution of nanosciences and nanotechnologies to solve the problems of many current drugs and vaccines.

Author: Maria José Alonso
Publisher: Springer
ISBN: 3319080849
Category : Medical
Languages : en
Pages : 478

View

Book Description
This authoritative volume focuses on emerging technologies in cancer nano medicine, characterized by their multi-functionality and potential to address simultaneously diverse issues of clinical relevance in the treatment of cancer. The book consists of sixteen chapters divided into six sections: 1) Biological Barriers in Cancer; 2) Tumor Targeting; 3) Targeting the Immune System; 4) Gene Therapy; 5) Nano theranostics and 6) Translational Aspects of Nano-Oncologicals. The volume starts with an introduction describing the biological barriers associated with cancer therapy and highlighting ways to overcome such barriers through the use of nanotechnology. This is followed by an analysis of the two major targeting strategies currently under investigation in cancer therapy: namely, the targeting of cancer cells and the targeting of the immune system. In the first case, the book presents liposomal and polymer-based therapies, including photodynamic approaches. In the second case, it analyzes in detail the possibility of either improving the efficiency of the immune system toward preventing cancer progression (cancer immunomodulation) or generating responses against specific cancer antigens (cancer vaccines). Beyond these targeting options, Nano-Oncologicals: New Targeting and Delivery Approaches presents the most recent technological advances in the area of nucleic acid-based therapies, along with those in the area of theranostics, where the design of multifunctional nano carriers becomes vital. Following the study of the most promising nanotechnologies around the development of nano-oncologicals, the book ends with an overview of regulatory and toxicological issues, which are critical in their translational pathway, and the presentation of a nucleic acid-based therapy case-study. This book is an important resource for scientists interested in the design and development of anticancer nanotechnologies and also to those aiming to push their technology through clinical development.

Author: V. P. Torchilin
Publisher: Imperial College Press
ISBN: 186094907X
Category : Technology & Engineering
Languages : en
Pages : 758

View

Book Description
Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications. This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, biomedical engineering, physiology, experimental and clinical medicine, and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting, as well as in more specialized topics of using nanoparticulate-mediated drug delivery approaches in the individual areas of clinical medicine. Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences. Sample Chapter(s). Chapter 1: Introduction. Nanocarriers for Drug Delivery: Needs and Requirements (442 KB). Contents: Nanoparticle Flow: Implications for Drug Delivery (A T Florence); Polymer Micelles as Drug Carriers (E V Batrakova et al.); Lipoproteins as Pharmaceutical Carriers (S Liu et al.); Dendrimers as Nanoparticular Drug Carriers (S Svenson & D A Tomalia); Cells and Cell Ghosts as Drug Carriers (J M Lanao & M L Sayalero); Magnetic Nanoparticles as Drug Carriers (U O Hnfeli & M Chastellain); Liposomal Drug Carriers in Cancer Therapy (A A Gabizon); Delivery of Nanoparticles to the Cardiovascular System (B-A Khaw); Nanoparticles for Targeting Lymphatics (W Phillips); Nanoparticular Carriers for Ocular Drug Delivery (A Sanchez & M J Alonso); and other papers. Readership: Graduate students, academics in nanomedicine, clinicians, pharmacologists, pharmacists, bioengineers, researchers in biotechnology and diagnostic imaging."

Author: Smadar Cohen
Publisher: CRC Press
ISBN: 9780824797539
Category : Science
Languages : en
Pages : 536

View

Book Description
This practical guide offers concise coverage of the scientific and pharmaceutical aspects of protein delivery from controlled release microparticulate systems-emphasizing protein stability during encapsulation and release.

Author: Abraham J. Domb
Publisher: Amer Scientific Pub
ISBN: 9781588830890
Category : Medical
Languages : en
Pages : 389

View

Book Description

Author: Jeffrey L. Cleland
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 384

View

Book Description
Presents an updated review of the recent research in formulation and delivery of proteins and peptides. Examines measurement and characterization of degradation products formed during storage, degradation mechanisms, and model systems designed to predict formulation stability. Discusses stabilization of proteins and peptides through lyophilization and focuses on the use of FTIR as a tool for understanding the role of excipients during lyophilization. Describes potential new routes and methods of delivery such as depot systems based on biodegradable polymers and aerosol systems for pulmonary delivery.

Author: Vinod Kumar Yata
Publisher: Springer Nature
ISBN: 3030471209
Category : Technology & Engineering
Languages : en
Pages : 352

View

Book Description
This book is the third volume on this subject and focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.

Author: Gregory Gregoriadis
Publisher: Springer Science & Business Media
ISBN: 1489901272
Category : Medical
Languages : en
Pages : 294

View

Book Description
Proceedings of a NATO ASI held in Cape Sounion Beach, Greece, June 24-July 5, 1997

Author: Lynda M. Sanders
Publisher: Springer Science & Business Media
ISBN: 0306468034
Category : Science
Languages : en
Pages : 447

View

Book Description
Thirteen chapters by industrial and academic authorities in this rapidly evolving field present detailed case histories and reviews of current sophisticated protein-drug delivery technologies. Highlights include a comprehensive overview of insulin delivery and a discussion of the use of biodegradable microspheres.