Guide to Research Techniques in Neuroscience PDF Download

Author: Matt Carter
Publisher: Academic Press
ISBN: 0323915612
Category : Medical
Languages : en
Pages : 416

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Book Description
Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more Clear, straightforward explanations of each technique for anyone new to the field A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture Detailed recommendations on where to find protocols and other resources for specific techniques "Walk-through" boxes that guide readers through experiments step-by-step

Author: Huangui Xiong
Publisher: Springer
ISBN: 9781493952168
Category : Medical
Languages : en
Pages : 0

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Book Description
Current Laboratory Methods in Neuroscience Research is a research manual for both students and seasoned researchers. It focuses on commonly-used techniques employed in neuroscience research, presented in a simple, step-by-step manner for laboratory use. The manual also offers a “blueprint” for bench-to-bedside research designed to facilitate multidisciplinary neuroscience pursuits. Sections include coverage of neurohistological techniques, in vitro preparations, leukocyte isolation and application in neuroscience, standard laboratory nucleic acid and protein detections, nanomedicine, bioimaging, neuroelectrophysiology, immunohistochemistry and autoradiography, analysis of gene expression, and animal models.

Author:
Publisher: Elsevier
ISBN: 008053645X
Category : Science
Languages : en
Pages : 475

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Book Description
The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike. Direct application of PCR to fresh or frozen clinical specimens (e.g., blood and solid tissue) Complete retrieval of novel expressed genes by PCR without screening a library Quantitation by PCR Mutagenesis by PCR PCR in AIDS research Simple and effective protocols for PCR on archival specimens

Author:
Publisher: Elsevier
ISBN: 0080536476
Category : Mathematics
Languages : en
Pages : 449

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Book Description
In this volume contemporary methods designed to provide insights into, mathematical structure for, and predictive inferences about neuroendocrine control mechanisms are presented. Collates an array of contemporary techniques for analysis of neuroendocrine data Discusses current problems in and solutions to neurohormone pulse analysis Identifies relevant software available

Author: Carlo Laing
Publisher: Oxford University Press
ISBN: 0199235074
Category : Mathematics
Languages : en
Pages : 399

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Book Description
Great interest is now being shown in computational and mathematical neuroscience, fuelled in part by the rise in computing power, the ability to record large amounts of neurophysiological data, and advances in stochastic analysis. These techniques are leading to biophysically more realistic models. It has also become clear that both neuroscientists and mathematicians profit from collaborations in this exciting research area.Graduates and researchers in computational neuroscience and stochastic systems, and neuroscientists seeking to learn more about recent advances in the modelling and analysis of noisy neural systems, will benefit from this comprehensive overview. The series of self-contained chapters, each written by experts in their field, covers key topics such as: Markov chain models for ion channel release; stochastically forced single neurons and populations of neurons; statistical methods for parameterestimation; and the numerical approximation of these stochastic models.Each chapter gives an overview of a particular topic, including its history, important results in the area, and future challenges, and the text comes complete with a jargon-busting index of acronyms to allow readers to familiarize themselves with the language used.

Author: Eddie Harmon-Jones
Publisher: Guilford Press
ISBN: 1462506275
Category : Psychology
Languages : en
Pages : 371

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Book Description
Straightforward and practical, this is the first book to provide detailed guidance for using neurobiological methods in the study of human social behavior, personality, and affect. Each chapter clearly introduces the method at hand, provides examples of the method's applications, discusses its strengths and limitations, and reviews concrete experimental design considerations. Written by acknowledged experts, chapters cover neuroimaging techniques, genetic measurement, hormonal methods, lesion studies, startle eyeblink responses, facial electromyography, autonomic nervous system responses, and modeling based on neural networks.

Author: Uwe Windhorst
Publisher: Springer Science & Business Media
ISBN: 3642585523
Category : Medical
Languages : en
Pages : 1336

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Book Description
An overview of the techniques used in modern neuroscience research with the emphasis on showing how different techniques can optimally be combined in the study of problems that arise at some levels of nervous system organization. This is essentially a working tool for the scientist in the laboratory and clinic, providing detailed step-by-step protocols with tips and recommendations. Most chapters and protocols are organized such that they can be used independently, while cross-references between the chapters, a glossary, a list of suppliers and appendices provide further help.

Author: Flavio Fröhlich
Publisher: Academic Press
ISBN: 0128015861
Category : Medical
Languages : en
Pages : 484

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Book Description
Studying brain networks has become a truly interdisciplinary endeavor, attracting students and seasoned researchers alike from a wide variety of academic backgrounds. What has been lacking is an introductory textbook that brings together the different fields and provides a gentle introduction to the major concepts and findings in the emerging field of network neuroscience. Network Neuroscience is a one-stop-shop that is of equal use to the neurobiologist, who is interested in understanding the quantitative methods employed in network neuroscience, and to the physicist or engineer, who is interested in neuroscience applications of mathematical and engineering tools. The book spans 27 chapters that cover everything from individual cells all the way to complex network disorders such as depression and autism spectrum disorders. An additional 12 toolboxes provide the necessary background for making network neuroscience accessible independent of the reader’s background. Dr. Flavio Frohlich wrote this book based on his experience of mentoring dozens of trainees in the Frohlich Lab, from undergraduate students to senior researchers. The Frohlich lab pursues a unique and integrated vision that combines computer simulations, animal model studies, human studies, and clinical trials with the goal of developing novel brain stimulation treatments for psychiatric disorders. The book is based on a course he teaches at UNC that has attracted trainees from many different departments, including neuroscience, biomedical engineering, psychology, cell biology, physiology, neurology, and psychiatry. Dr. Frohlich has consistently received rave reviews for his teaching. With this book he hopes to make his integrated view of neuroscience available to trainees and researchers on a global scale. His goal is to make the book the training manual for the next generation of (network) neuroscientists, who will be fusing biology, engineering, and medicine to unravel the big questions about the brain and to revolutionize psychiatry and neurology. Easy-to-read, comprehensive introduction to the emerging field of network neuroscience Includes 27 chapters packed with information on topics from single neurons to complex network disorders such as depression and autism Features 12 toolboxes serve as primers to provide essential background knowledge in the fields of biology, mathematics, engineering, and physics

Author: Adrian C. Michael
Publisher: CRC Press
ISBN: 1420005863
Category : Medical
Languages : en
Pages : 540

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Book Description
Since the first implant of a carbon microelectrode in a rat 35 years ago, there have been substantial advances in the sensitivity, selectivity and temporal resolution of electrochemical techniques. Today, these methods provide neurochemical information that is not accessible by other means. The growing recognition of the versatility of electrochemi

Author: Eugene M. Izhikevich
Publisher: MIT Press
ISBN: 0262514206
Category : Medical
Languages : en
Pages : 459

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Book Description
Explains the relationship of electrophysiology, nonlinear dynamics, and the computational properties of neurons, with each concept presented in terms of both neuroscience and mathematics and illustrated using geometrical intuition. In order to model neuronal behavior or to interpret the results of modeling studies, neuroscientists must call upon methods of nonlinear dynamics. This book offers an introduction to nonlinear dynamical systems theory for researchers and graduate students in neuroscience. It also provides an overview of neuroscience for mathematicians who want to learn the basic facts of electrophysiology. Dynamical Systems in Neuroscience presents a systematic study of the relationship of electrophysiology, nonlinear dynamics, and computational properties of neurons. It emphasizes that information processing in the brain depends not only on the electrophysiological properties of neurons but also on their dynamical properties. The book introduces dynamical systems, starting with one- and two-dimensional Hodgkin-Huxley-type models and continuing to a description of bursting systems. Each chapter proceeds from the simple to the complex, and provides sample problems at the end. The book explains all necessary mathematical concepts using geometrical intuition; it includes many figures and few equations, making it especially suitable for non-mathematicians. Each concept is presented in terms of both neuroscience and mathematics, providing a link between the two disciplines. Nonlinear dynamical systems theory is at the core of computational neuroscience research, but it is not a standard part of the graduate neuroscience curriculum—or taught by math or physics department in a way that is suitable for students of biology. This book offers neuroscience students and researchers a comprehensive account of concepts and methods increasingly used in computational neuroscience. An additional chapter on synchronization, with more advanced material, can be found at the author's website, www.izhikevich.com.