The Analysis of Case-control Studies PDF Download

Author: Norman E. Breslow
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 352

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Author: Norman E. Breslow
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 440

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Author: Ole Møller Jensen
Publisher: IARC
ISBN: 9283211952
Category : Medical
Languages : en
Pages : 295

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Book Description
Data obtained by population based cancer registries have a pivotal role in cancer control. Now also available in Spanish and French, this volume, which contains 15 authored chapters and four useful appendices, remains a standard reference for those planning to establish new cancer registries and those keen to adopt recognized methodologies. Information is given on the techniques required to collect, store, analyse and interpret data.

Author: Raphael. L.C Araújo
Publisher: Springer
ISBN: 3319713248
Category : Medical
Languages : en
Pages : 348

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This book introduces and discusses the most important aspects of clinical research methods and biostatistics for oncologists, pursuing a tailor-made and practical approach. Evidence-based medicine (EBM) has been in vogue in the last few decades, particularly in rapidly advancing fields such as oncology. This approach has been used to support decision-making processes worldwide, sparking new clinical research and guidelines on clinical and surgical oncology. Clinical oncology research has many peculiarities, including specific study endpoints, a special focus on survival analyses, and a unique perspective on EBM. However, during medical studies and in general practice, these topics are barely taught. Moreover, even when EBM and clinical cancer research are discussed, they are presented in a theoretical fashion, mostly focused on formulas and numbers, rather than on clinical application for a proper literature appraisal. Addressing that gap, this book discusses more practical aspects of clinical research and biostatistics in oncology, instead of relying only on mathematical formulas and theoretical considerations. Methods and Biostatistics in Oncology will help readers develop the skills they need to understand the use of research on everyday oncology clinical practice for study design and interpretation, as well to demystify the use of EBM in oncology.

Author: Elsevier Science & Technology Books
Publisher:
ISBN: 9780121476724
Category : Cancer
Languages : en
Pages : 426

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Author: H. Acker
Publisher: Springer Science & Business Media
ISBN: 3642823408
Category : Medical
Languages : en
Pages : 328

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Malignant growth of cells is often characterized by disorganization of tissue structure, abnormal blood vessel development, and insuffi cient vascular supply. As a consequence, the cancer cells grow in a three-dimensional pattern in atypical microenvironments which include physical, chemical, and nutritional stresses. Necrosis often develops some distance away from the blood vessels. In association with an inherent instability in malignant cell populations, and also because of the changing micromilieu, significant cellular heteroge neity emerges with regard to various phenotypic characteristics. Both biological behavior and responses to therapeutic agents can be affected. A variety of in vitro and in vivo experimental models exist for research on properties of cancer cells during growth. The multicell spheroid model was developed as a system of intermediate complexity in which three dimensional growth of cells enhances cell-cell interactions and creates micro environments that simulate the conditions in intervascular microregions of tumors or microme tastatic foci. Spheroids may change their cellular characteristics with changing environments during growth. These can be studied under controlled conditions in vitro. Interest in details of experimental methods for this model system stimulated the organization of the First International Conference in Rochester, NY in 1980, the Proceedings of which were summarized in Cancer Research in 1981. Since then there has been a rapid increase in the use of this model system, and increased research on the significance of cell-cell and cell-microenvironment interactions in biology in general.

Author: Gauri Misra
Publisher: Academic Press
ISBN: 0323898173
Category : Science
Languages : en
Pages : 222

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Protocol Handbook for Cancer Biology brings together a comprehensive collection of the methods used for cancer assessment, diagnostics, and therapeutics. Various protocols are discussed along with alternative strategies, including the advantages and limitations of techniques that have been used in labs globally. These protocols are presented by cancer biology experts based on their real-world experience. The protocols in this book will be a valuable resource for cancer researchers and graduate students, who can utilize the techniques described to conduct research more efficiently and successfully. Presents comprehensive protocols used for cancer assessment, diagnostics, and therapeutics all in one place Encompasses alternative strategies considering the requirements of the end user and taking into consideration diverse research settings Discusses limitations and advantages of each method in experimental design and execution, thus saving time during the research process

Author: N. E. Breslow
Publisher:
ISBN:
Category : Investigacion
Languages : en
Pages :

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Author: Norman E. Breslow
Publisher: IARC Scientific Publications
ISBN: 9789283201328
Category : Language Arts & Disciplines
Languages : en
Pages : 0

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The case control study is the major epidemiological approach used to identify risk factors for cancer. This textbook explains the statistical

Author: Margot M. Ip
Publisher: Springer Science & Business Media
ISBN: 9780306463976
Category : Medical
Languages : en
Pages : 366

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This book is a bench manual that provides in one volume all theimportant and unique technologies necessary to studies of mammarygland biology and breast cancer. The chapters are written by expertsin each area with an emphasis on nitty-gritty details that are keypoints for the successful use of a method. Sections include "in""vivo" model systems, special techniques for "in vivo"studies, "in vitro" model systems, and molecular analysis and genetransfer techniques.