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Methods and Devices for Noninvasive Physiologic Fluid Volume Assessment

Methods and Devices for Noninvasive Physiologic Fluid Volume Assessment PDF Author: Matthew Li (Ph. D.)
Publisher:
ISBN:
Category :
Languages : en
Pages : 154

Book Description
Fluid volume status is a physiologic parameter that currently lacks a reliable diagnostic tool. Volume control becomes an issue during sickness and/or stress (physical and mental) in a wide range of populations. Unfortunately, current diagnostics suffer from being imprecise, invasive, and/or easily confounded and cannot unambiguously and practically inform volume status. There exists a need for a tool that can inform individuals and clinicians of fluid status in a noninvasive, rapid, and reliable manner. Drawing on the molecular sensitivity of IH nuclear magnetic resonance (NMR), we explored the ability of NMR methods to quantitate physiologic fluid volume changes. We first proved that NMR methods could detect volume changes in an animal model of dehydration. Correlation between NMR value changes in specific tissues and clinical tools used to assess dehydration validate NMR as a viable tool. We then proceeded to design and fabricate practical NMR sensors that could be easily integrated into the clinic. New methods of magnetic instrument design optimized for both field strength and spatial resolution were developed resulting in compact device prototypes with signal fidelity rivaling those of impractical commercial systems. Finally, we explored the ability of these devices to detect intravascular fluid changes during hemodialysis. Our methods and devices were able to detect intravascular blood property changes associated with blood dilution, in addition to overall fluid volume changes due to hemodialysis therapy. These results, methods, and devices provide the foundation and framework for the integration of NMR-based personalized fluid volume assessment into standard clinical practice.

Methods and Devices for Noninvasive Physiologic Fluid Volume Assessment

Methods and Devices for Noninvasive Physiologic Fluid Volume Assessment PDF Author: Matthew Li (Ph. D.)
Publisher:
ISBN:
Category :
Languages : en
Pages : 154

Book Description
Fluid volume status is a physiologic parameter that currently lacks a reliable diagnostic tool. Volume control becomes an issue during sickness and/or stress (physical and mental) in a wide range of populations. Unfortunately, current diagnostics suffer from being imprecise, invasive, and/or easily confounded and cannot unambiguously and practically inform volume status. There exists a need for a tool that can inform individuals and clinicians of fluid status in a noninvasive, rapid, and reliable manner. Drawing on the molecular sensitivity of IH nuclear magnetic resonance (NMR), we explored the ability of NMR methods to quantitate physiologic fluid volume changes. We first proved that NMR methods could detect volume changes in an animal model of dehydration. Correlation between NMR value changes in specific tissues and clinical tools used to assess dehydration validate NMR as a viable tool. We then proceeded to design and fabricate practical NMR sensors that could be easily integrated into the clinic. New methods of magnetic instrument design optimized for both field strength and spatial resolution were developed resulting in compact device prototypes with signal fidelity rivaling those of impractical commercial systems. Finally, we explored the ability of these devices to detect intravascular fluid changes during hemodialysis. Our methods and devices were able to detect intravascular blood property changes associated with blood dilution, in addition to overall fluid volume changes due to hemodialysis therapy. These results, methods, and devices provide the foundation and framework for the integration of NMR-based personalized fluid volume assessment into standard clinical practice.

Hemodynamic Monitoring

Hemodynamic Monitoring PDF Author: Michael R. Pinsky
Publisher: Springer
ISBN: 3319692690
Category : Medical
Languages : en
Pages : 476

Book Description
This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.

Fetal Heart Rate Monitoring

Fetal Heart Rate Monitoring PDF Author: Roger K. Freeman
Publisher: Lippincott Williams & Wilkins
ISBN: 1451171706
Category : Medical
Languages : en
Pages : 281

Book Description
Fetal heart rate monitoring affects the lives of millions of women and infants every year in the United States alone. Used by all members of the obstetric team - nurses, students, midwives, and physicians – it is the primary method to assess fetal oxygenation in both the antepartum and intrapartum setting. Improving outcomes and promoting patient safety depends upon correct use and interpretation of fetal heart rate monitoring, and is crucial to daily obstetric practice. This fourth edition provides the obstetrical team a framework within which to interpret and understand fetal heart rate tracings and their implications. The text covers key issues as the physiological basis for monitoring, a discussion of fetal hypoxemia and neonatal encephalopathy, instrumentation and pattern recognition. In addition to an in-depth review of the standardized NICHD nomenclature and three-tiered FHR Category approach, there are chapters on intrapartum and antepartum management as well as fetal central nervous system effects on monitor patterns. Since fetal monitoring is primarily a screening tool there are also discussions on the use of backup methods for evaluation of abnormal patterns. This 4th edition also brings the addition of Lisa A. Miller CNM, JD, who provides a nursing and midwifery perspective as well an enhanced legal and risk management review. This new fourth edition includes: Review of neonatal encephalopathy and recent studies on CP Currentinformation and discussion of most recent NICHD panel recommendations, both antepartum and intrapartum New chapter on Pitfalls in EFM Detailed chapter on risk management, liability & documentation New section on fetal maternal hemorrhage Update on new instrumentation Crucial information on maternal/fetal coincidence and FDA warnings All chapters include updated practice tips and clinical implications for the entire obstetric team Plus, with this edition clinicians have access to a companion website with full text and an image bank for fast & simplified clinical review.

Noninvasive Physiological Measurement

Noninvasive Physiological Measurement PDF Author: James C. Lin
Publisher: CRC Press
ISBN: 100383745X
Category : Technology & Engineering
Languages : en
Pages : 515

Book Description
This book explains the principles and techniques of microwave physiological sensing and introduces fundamental results of the noninvasive sensing of physiological signatures, vital signs, as well as life detection. Specifically, noninvasive microwave techniques for contact, contactless, and remote sensing of circulatory and respiratory movements and physiological volume changes are discussed. Noninvasive Physiological Measurement: Wireless Microwave Sensing, is written by a pioneering researcher in microwave noninvasive physiological sensing and leading global expert in microwaves in biology and medicine. The book reviews current advances in noninvasive cardiopulmonary sensing technology and measurement. It includes measurements of the vital signs and physiological signatures from laboratory and clinical testing. The book discusses the applicable domains and scenarios in which there is an interaction of radio frequency (RF) and microwaves with biological matter in gas, fluid, or solid form, both from inside and outside of the human or animal body. The book also provides examples for healthcare monitoring and diagnostic applications through wearables, devices, or remote contactless sensors for physiological signals and signature, vital signs, and body motion sensing. This book is an essential guide to understanding the human body’s interaction with microwaves and noninvasive physiological sensing and monitoring. This book is intended for researchers and professionals in biomedical, electrical, and computer engineering with an interest in antenna, sensors, microwaves, signal processing, and medical applications. It will also be of interest to healthcare professionals, technologists, and practitioners interested in noninvasive physiological sensing and patient monitoring.

Intra-Abdominal Hypertension

Intra-Abdominal Hypertension PDF Author: Manu Malbrain
Publisher: Cambridge University Press
ISBN: 0521149398
Category : Medical
Languages : en
Pages : 255

Book Description
Practical clinical handbook reviewing all aspects of the diagnosis and management of intra-abdominal hypertension; essential reading for all critical care staff.

Solving Problems with NMR Spectroscopy

Solving Problems with NMR Spectroscopy PDF Author: Atta-ur Rahman
Publisher: Academic Press
ISBN: 0124116132
Category : Science
Languages : en
Pages : 535

Book Description
Solving Problems with NMR Spectroscopy, Second Edition, is a fully updated and revised version of the best-selling book. This new edition still clearly presents the basic principles and applications of NMR spectroscopy with only as much math as is necessary. It shows how to solve chemical structures with NMR by giving many new, clear examples for readers to understand and try, with new solutions provided in the text. It also explains new developments and concepts in NMR spectroscopy, including sensitivity problems (hardware and software solutions) and an extension of the multidimensional coverage to 3D NMR. The book also includes a series of applications showing how NMR is used in real life to solve advanced problems beyond simple small-molecule chemical analysis. This new text enables organic chemistry students to choose the most appropriate NMR techniques to solve specific structures. The problems provided by the authors help readers understand the discussion more clearly and the solution and interpretation of spectra help readers become proficient in the application of important, modern 1D, 2D, and 3D NMR techniques to structural studies. Explains and presents the most important NMR techniques used for structural determinations Offers a unique problem-solving approach for readers to understand how to solve structure problems Uses questions and problems, including discussions of their solutions and interpretations, to help readers understand the fundamentals and applications of NMR Avoids use of extensive mathematical formulas and clearly explains how to implement NMR structure analysis Foreword by Nobel Prize winner Richard R. Ernst New to This Edition Key developments in the field of NMR spectroscopy since the First Edition in 1996 New chapter on sensitivity enhancement, a key driver of development in NMR spectroscopy New concepts such as Pulse Field Gradients, shaped pulses, and DOSY (Diffusion Order Spectroscopy) in relevant chapters More emphasis on practical aspects of NMR spectroscopy, such as the use of Shigemi tubes and various types of cryogenic probes Over 100 new problems and questions addressing the key concepts in NMR spectroscopy Improved figures and diagrams More than 180 example problems to solve, with detailed solutions provided at the end of each chapter

Neuro-Urology

Neuro-Urology PDF Author: Roger Dmochowski
Publisher:
ISBN: 9783319909967
Category : Gynecology
Languages : en
Pages : 453

Book Description
This volume is a useful handbook for medical doctors involved in the diagnosis and treatment of neuro-urological problems. The first section reviews the relevant neuro-anatomy and neuro-physiology and provides a practical overview of specific neuro-urological pathologic conditions. The second section discusses the various clinical entities that can be encountered and focuses on the clinical entities neuro-urological consquences. The third section is devoted to the different diagnostic possibilities. Internationally accepted algorithms are presented and put into perspective. Section 4 deals with the triad of major clinical problems in this area: urinary (incontinence, retention and voiding dysfunction as well as upper urinary tract problems), anorectal (faecal incontinence and constipation) and sexual (erectile dysfunction and ejaculatory failure) dysfunctions. The final section covers the specific management of patients with neuro-urological problems and describes conservative and surgical treatments, providing the most recent information. Throughout, the text is accompanied by numerous illustrated case reports and discussions as well as tips and tricks based on the personal experience of the different authors.

Fluid Resuscitation

Fluid Resuscitation PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309064813
Category : Medical
Languages : en
Pages : 208

Book Description
Historically, 20% of all injured combatants die on the battlefield before they can be evacuated to a field hospital. Blood lossâ€"hemorrhageâ€"is the single major cause of death among those killed in action whose lives might otherwise be saved. Fluid resuscitation and the treatment of hypovolemia (the abnormally decreased volume of circulating fluid in the body) offer the greatest opportunity for reducing mortality and morbidity associated with battlefield casualties. In Fluid Resuscitation, a committee of experts assess current resuscitation fluids and protocols for the treatment of combat casualties and make recommendations for future research. Chapters focus on the pathophysiology of acute hemorrhagic shock, experience with and complications of fluid resuscitation, novel approaches to the treatment of shock, protocols of care at the site of injury, and future directions for research. The committee explicitly describes the similarities and differences between acute medical care during combat and civilian emergency trauma care. Fluid Resuscitation should help energize and focus research in both civilian and military emergency care and help save the lives of citizens and soldiers alike.

Surgical Technology - E-Book

Surgical Technology - E-Book PDF Author: Joanna Kotcher
Publisher: Elsevier Health Sciences
ISBN: 0323430562
Category : Medical
Languages : en
Pages : 1120

Book Description
Learn to deliver the best patient care before, during, and after surgery with Surgical Technology: Principles and Practice, 7th Edition. Within its pages you’ll find comprehensive coverage of all the updated AST Core Curriculum components — including all aspects of health care sciences; technological sciences; patient care concepts; preoperative, intraoperative, and postoperative care; surgical procedures; and professional practice. But what you won’t find in any other surg tech book is an incredibly reader-friendly approach featuring conversational, mentor-like guidance and loads of full-color pictures and illustrations. You’ll also have an abundance of helpful learning features at your disposal — like case studies, review questions, and online learning activities — that will help you easily master important concepts and apply that learning to professional practice. No other surgical technology text better prepares you for the challenges of professional practice! Comprehensive coverage addresses all areas of the AST Core Curriculum for Surgical Technology. Reader-friendly writing style and organization utilizes a mentoring approach to present content within the building blocks of fundamentals, aseptic technique, the role and function of the surgical technologist, and surgical procedures. Consistent chapter format breaks down each surgical procedure in an easy-to-understand way making it easy for students to comprehend the key elements of more than 70 procedures. Experienced author/consulting editor team lends a breadth of experience for a well-rounded view of life in the operating room and multiple perspective focused on quality patient care. Over 1,200 full-color illustrations and clinical photos bring concepts and procedures to life. Robust practice opportunities include review questions and case studies at the end of each chapter along with crosswords, additional review questions, and surgical practice videos found on the Evolve companion website. Learning objectives serve as checkpoints for comprehension and as study tools in preparation for examinations. Key terminology appears in boldface and in color within chapter discussions and are defined and cross-referenced to chapters in a back-of-book glossary. Key concepts are covered in a bulleted list at the end of each chapter discussion to summarize and rephrase chapter concepts. References and bibliographies provide a listing of in-text and additional citations of scientific research. Pathology appendix summarizes the most commonly seen pathological processes and organizes them by body system. Website mentions are highlighted within the text to draw readers’ attention to available videos in the Evolve Resources and suggested websites to visit for additional information on content covered.

Functional Hemodynamic Monitoring

Functional Hemodynamic Monitoring PDF Author: Michael R. Pinsky
Publisher: Springer Science & Business Media
ISBN: 3540269002
Category : Medical
Languages : en
Pages : 414

Book Description
This is the newest volume in the softcover series "Update in Intensive Care Medicine". It takes a novel, practical approach to analyzing hemodynamic monitoring, focusing on the patient and outcomes based on disease, treatment options and relevance of monitoring to direct patient care. It will rapidly become a classic in the approach to patient monitoring and management during critical illness.