Metabolic and Immune Disorders Associated with Psychiatric Disease: Potential Etiology and Pathway for Treatment PDF Download

Author: Richard Eugene Frye
Publisher: Frontiers Media SA
ISBN: 2889639584
Category :
Languages : en
Pages : 251

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Author: Katherine J. Aitchison
Publisher: CRC Press
ISBN: 9781853174353
Category : Medical
Languages : en
Pages : 152

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The new edition of this popular handbook has been thoroughly updated to include the latest data concerning treatment of first-episode patients. Drawing from their experience, the authors discuss the presentation and assessment of the first psychotic episode and review the appropriate use of antipsychotic agents and psychosocial approaches in effective management.

Author: Bernhard Baune
Publisher: Academic Press
ISBN: 0128131772
Category : Medical
Languages : en
Pages : 594

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Book Description
Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. - Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics - Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry - Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

Author: Jonas H. Ellenberg
Publisher: CRC Press
ISBN: 9780824788230
Category : Medical
Languages : en
Pages : 600

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Book Description
This comprehensive reference provides a detailed overview of current concepts regarding the cause of Parkinson's disease-emphasizing the issues involved in the design, implementation, and analysis of epidemiological studies of parkinsonism.

Author: Ole Köhler-Forsberg
Publisher: Frontiers Media SA
ISBN: 2889662691
Category : Medical
Languages : en
Pages : 130

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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Author: Alexander Choukèr
Publisher: Springer Nature
ISBN: 3030169960
Category : Medical
Languages : en
Pages : 756

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This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology. The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Author: Roberto Canitano
Publisher: Frontiers Media SA
ISBN: 2889195309
Category : Autism
Languages : en
Pages : 162

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Book Description
Developing novel and more effective treatments that improve quality of life for individuals with autism spectrum disorders is urgently needed. To date a wide range of behavioral interventions have been shown to be safe and effective for improving language and cognition and adaptive behavior in children and adolescents with ASD. However many people with ASD can receive additional benefit from targeted pharmacological interventions. One of the major drawback in setting up therapeutics intervention is the remarkable individual differences found across individuals with ASD. As a matter of fact the medications that are currently available address only symptoms associated with ASD and not the core domains of social and communication dysfunction. The pathogenesis paradigm shift of ASD towards synaptic abnormalities moved the research to pathway to disease that involve multiple systems and that are becoming the forefront of ASD treatment and are pointing toward the development of new targeted treatments. Some new therapeutics have been tested and others are being studied. In this context single gene disorders frequently associated with ASD such as Rett Syndrome, Fragile X and Tuberous Sclerosis have been of significant aid as neurobiology of these disorders is more clear and has a potential to shed light on the altered signaling in ASD. However much research is needed to further understand the basic mechanisms of disease and the relationship to idiopathic ASD. Clinical trials in children are underway with agents directed to core symptoms and to the associated disorders in the search of new therapeutics and progress are expected with possible new option for therapeutics in ASD in the upcoming future. Children and Adolescents with ASD and their families can provide important information about their experience with new treatments and this should be a priority for future research. In addition, research performed on genetic mouse models of ASD will keep on providing useful information on the molecular pathways dysrupted in the disease, thus contributing to identify novel drug targets.

Author: N. Sartorius
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318026042
Category : Medical
Languages : en
Pages : 202

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Book Description
This publication presents evidence about the magnitude and severe consequences of comorbidity of mental and physical illnesses from a personal and societal perspective. Leading experts address the huge burden of co-morbidity to the affected individual as well as the public health aspects, the costs to society and interaction with factors stemming from the context of socioeconomic developments. The authors discuss the clinical challenge of managing cardiovascular illnesses, cancer, infectious diseases and other physical illness when they occur with a range of mental and behavioral disorders, including substance abuse, eating disorders and anxiety. Also covered are the organization of health services, the training of different categories of health personnel and the multidisciplinary engagement necessary to prevent and manage comorbidity effectively. The book is essential reading for general practitioners, internists, public health specialists, psychiatrists, cardiologists, oncologists, medical educationalists and other health care professionals.

Author: Abul K. Abbas
Publisher: Elsevier Health Sciences
ISBN: 1437735738
Category : Medical
Languages : en
Pages : 560

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Book Description
Cellular and Molecular Immunology takes a comprehensive yet straightforward approach to the latest developments in this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present sweeping updates in this new edition to cover antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more. This reference is the up-to-date and readable textbook you need to master the complex subject of immunology. Recognize the clinical relevance of the immunology through discussions of the implications of immunologic science for the management of human disease. Grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions. Stay abreast of the latest advances in immunology and molecular biology through extensive updates that cover cytokines, innate immunity, leukocyte-endothelial interactions, signaling, costimulation, and more. Visualize immunologic processes more effectively through a completely revised art program with redrawn figures, a brighter color palette, and more 3-dimensional art. Find information more quickly and easily through a reorganized chapter structure and a more logical flow of material.

Author: Alexandrina Ferreira Mendes
Publisher: Frontiers Media SA
ISBN: 288945729X
Category :
Languages : en
Pages : 255

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Book Description
Chronic diseases are increasingly recognized as involving low grade inflammation, that is, a self-perpetuating tissue response to stress caused by exogenous or endogenous triggers, that progressively evokes danger-associated molecular pattern release, ultimately driving tissue damage and loss of function. This response is frequently unapparent clinically, thus the designation "low grade". This eBook comprises nineteen reviews and original articles that provide the most updated knowledge on the causes and roles of this inflammatory response in a variety of diseases and conditions. The editorial that precedes these articles not only summarizes each one, but provides a broader interpretation of the role of inflammation in health and a variety of disease conditions, the underlying mechanisms and the targets more promising for therapy. Finally, it also highlights the most relevant and emerging research topics that are already shaping future directions for the development of more fine-tuned and innovative therapies.