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Author: M. W. Miller Publisher: Springer Science & Business Media ISBN: 1468432796 Category : Science Languages : en Pages : 545
Book Description
Research on the study of membrane toxicity has advanced a great deal in a relatively short period of time, prompting scientists to re-examine the problems associated with carriers, receptors and reactors to toxic substances. This book presents current research on the responses of membranes to toxic sub stances both by direct observation of macromolecules reacting with these substances and by inference from data on the bio chemical responses of cells and cell fractions. Two basic areas of membrane toxicity are analyzed by a large number and variety of scientists in this field. The first area is the effect of various toxic substances on membrane structure and function. The second area is where the membrane serves as the site of rate limiting step of the transport of various toxic substances. The aim of the book is to evaluate present concepts of membrane structure and function in relation to exposure to envir onmental toxicants. The book is divided into five sessions: 1. Xenobiotics and Membrane Transport 2. Cellular Responses to Toxins 3. Effects of Membranes and Receptors 4. Modification of Membrane Function by Toxicological Agents 5. Toxic Chemicals as Molecular Probes of Membrane Structure and Function Each paper is generally concluded by an edited discussion which contains many useful and interesting additional insights in each subject area. v ACKNOWLEDGEMENT We gratefully acknowledge the support provided for this conference by the U. S. Energy Research and Development Administration, the Environmental Protection Agency and the University of Rochester.
Author: M. W. Miller Publisher: Springer Science & Business Media ISBN: 1468432796 Category : Science Languages : en Pages : 545
Book Description
Research on the study of membrane toxicity has advanced a great deal in a relatively short period of time, prompting scientists to re-examine the problems associated with carriers, receptors and reactors to toxic substances. This book presents current research on the responses of membranes to toxic sub stances both by direct observation of macromolecules reacting with these substances and by inference from data on the bio chemical responses of cells and cell fractions. Two basic areas of membrane toxicity are analyzed by a large number and variety of scientists in this field. The first area is the effect of various toxic substances on membrane structure and function. The second area is where the membrane serves as the site of rate limiting step of the transport of various toxic substances. The aim of the book is to evaluate present concepts of membrane structure and function in relation to exposure to envir onmental toxicants. The book is divided into five sessions: 1. Xenobiotics and Membrane Transport 2. Cellular Responses to Toxins 3. Effects of Membranes and Receptors 4. Modification of Membrane Function by Toxicological Agents 5. Toxic Chemicals as Molecular Probes of Membrane Structure and Function Each paper is generally concluded by an edited discussion which contains many useful and interesting additional insights in each subject area. v ACKNOWLEDGEMENT We gratefully acknowledge the support provided for this conference by the U. S. Energy Research and Development Administration, the Environmental Protection Agency and the University of Rochester.
Author: E. Edward Bittar Publisher: JAI Press(NY) ISBN: 9780762301416 Category : Cell-mediated cytotoxicity Languages : en Pages : 0
Book Description
Cellular toxicology has entered a new era. No longer are we concerned only with necrotic cell death produced by severe, acute insult (often to multiple intracellular targets) leading to disruption of the cell membrane. New advances in molecular and cellular biology are allowing the dissection of mechanisms of cell death involving more subtle targets within the cell. Toxicology has been very important, not only in understanding the mechanisms, nature, and severity of toxicity and thereby helping in risk assessment, but toxicology has also played a very important role in helping to understand basic biological processes. Historically this has perhaps been most evident in the use of toxic agents to interfere with specific reactions in the body and hence help to dissect out the mechanisms of metabolic processes. For example, the use of chemical inhibitors was very important in understanding the process of oxidative phosphorylation, or the tricarboxylic acid cycle. More recent examples are seen herein where toxicology interfaces with, for example structural biology in the study of the cytoskeletal components and their interactions. Indirectly, an understanding of the mechanisms of endogenous protective systems also improves knowledge of basic cell biology. Toxic insult and manipulation of cell signalling and control mechanisms in cell growth and differentation also highlight how important the discipline of cell toxicity has been and will continue to be a major contributor to our understanding of basic issues in the biological and biomedical sciences. This book offers selected reviews of some of the principal molecular mechanisms of cell toxicity.
Author: G.R. Gobran Publisher: Elsevier ISBN: 0080457673 Category : Technology & Engineering Languages : en Pages : 481
Book Description
The rhizosphere in soil environments refers to the narrow zone of soil influenced by the root and exudates. Microbial populations in the rhizosphere can be 10 - 100 times larger than the populations in the bulk soil. Therefore, the rhizosphere is bathed in root exudates and microbial metabolites and the chemistry and biology at the soil-root interface is governed by biotic (plant roots, microbes) and abiotic (physical and chemical) interactions. The research on biotic and abiotic interactions in the rhizosphere should, thus, be an issue of intense interest for years to come. This book, which consists of 15 chapters, addresses a variety of issues on fundamentals of microscopic levels and the impact on food chain contamination and the terrestrial ecosystem. It is an essential reference work for chemists and biologists studying environmental systems, as well as earth, soil and environmental scientists.* 15 chapter book, which addresses a variety of issues on fundamentals of microscopic levels and the impact on food chain contamination and the terrestrial ecosystem
Author: Alberto Figoli Publisher: CRC Press ISBN: 1315735237 Category : Science Languages : en Pages : 332
Book Description
Focuses on the application of membrane technologies in removing toxic metals\metalloids from water. Particular attention is devoted to the removal of arsenic, uranium, and fluoride. These compounds are all existing in the earth’s crust at levels between two and five thousands micrograms per kg (parts per million) on average and these compounds can be considered highly toxic to humans, who are exposed to them primarily from air, food and water. In order to comply with the new maximum contaminant level, numerous studies have been undertaken to improve established treatments or to develop novel treatment technologies for removing toxic metals from contaminated surface and groundwater. Among the technologies available, applicable for water treatment, membrane technology has been identified as a promising technology to remove such toxic metals from water. The book describes both pressure driven (traditional processes, such as Nanofiltration, Reverse Osmosis, Ultrafiltration,etc) and more advanced membrane processes (such as forward osmosis, membrane distillation, and membrane bio-reactors) employed in the application of interest. Key aspect of this book is to provide information on both the basics of membrane technologies and on the results depending on the type of technology employed.
Author: National Research Council Publisher: National Academies Press ISBN: 0309052289 Category : Science Languages : en Pages : 322
Book Description
Diseases of the kidney, bladder, and prostate exact an enormous human and economic toll on the population of the United States. This book examines prevention of these diseases through the development of reliable markers of susceptibility, exposure, and effect and the promise that new technologies in molecular biology and sophisticated understanding of metabolic pathways, along with classical approaches to the study of nephrotoxicants and carcinogens, can be developed and prevention of the diseases achieved. The specific recommendations included in this book complement those made in the previous three volumes on biomarkers, Biologic Markers in Reproductive Toxicology (1989), Biologic Markers in Pulmonary Toxicology (1989), and Biologic Markers in Immunotoxicology (1991).
Author: Jean L. Bolognia Publisher: Elsevier Health Sciences ISBN: 0702084697 Category : Medical Languages : en Pages : 3312
Book Description
**Selected for Doody's Core Titles® 2024 in Dermatology**For dermatology residents and trainees, as well as those in clinical practice, Dermatology is the leading reference for understanding, diagnosing, and treating the full spectrum of skin disease—and is the key resource that residents rely on throughout their training and certification. Widely recognized for its easy-in, easy-out approach, this revised 5th Edition turns complex information into user-friendly visual content through the use of clear, templated chapters, digestible artwork, and easy-to-follow algorithms and tables. This two-volume masterwork provides complete, authoritative coverage of basic science, clinical practice of both adult and pediatric dermatology, dermatopathology, and dermatologic surgery—more than any other source, making it the gold standard reference in the field today. - Simplifies complex content in a highly accessible, highly visual manner, with 1,100+ tables; 2,600+ figures, including numerous disease classification algorithms as well as diagnostic and therapeutic pathways; and over 1,500 additional figures and tables online. - Utilizes weighted differential diagnosis tables and a "ladder" approach to therapeutic interventions. - Any additional digital ancillary content may publish up to 6 weeks following the publication date. - Features an intuitive organization and color-coded sections that allow for easy and rapid access to the information you need. - Retains an emphasis on clinicopathologic correlations, with photomicrographs demonstrating key histologic findings adjacent to clinical images of the same disorder. - Contains updated treatment information throughout, including immune checkpoint inhibitors, JAK inhibitors, and monoclonal antibodies for a wide range of conditions such as psoriasis, atopic dermatitis, alopecia areata, vitiligo, and skin cancers. - Provides up-to-date information on genetic and molecular markers and next-generation sequencing as it applies to dermatologists. - Features new videos, including cryosurgical and suturing techniques, treatment of rhinophyma via electrosection, and neuromodulator treatment of axillary hyperhidrosis. - Includes new WHO classifications of skin tumors, new FDA pregnancy drug labeling, and new ACR/EULAR criteria for vasculitis and lupus erythematosus. - Includes new sections on confocal microscopy and artificial intelligence.
Author: Jan Wilschut Publisher: CRC Press ISBN: 1000715620 Category : Medical Languages : en Pages : 927
Book Description
This balanced volume provides a broad and coherent overview of recent progress in membrane fusion research—highlighting an interdisciplinary treatment of the subject from the fields of biophysics, biochemistry, cell biology, virology, and biotechnology—in a single volume., Featuring easy-access sections on the general properties of membranes and applications of membrane fusion techniques, this valuable sourcebook outlines membrane structure, lipid polymorphism, and intermembrane forces ... covers membrane fusion in model systems ... presents the fusogenic properties of enveloped viruses ... discusses the fusion and flow of intracellular membranes and cell-cell fusion occurring during fertilization and myogenesis ... offers applications of membrane fusion techniques in cell-biological research and biotechnology ... and more. Supplying a comprehensive view of this exciting topic, Membrane Fusion is a working resource for molecular, cell, and membrane biologists; biophysicists; biochemists; virologists; biotechnologists; microbiologists; immunologists; physiologists; and graduate and medical school students in biophysics, biochemistry, physiology, virology, cell biology, and biotechnology.
Author: M. W. Miller
Author: M. W. Miller
Author: Mike Mickley
Author: E. Edward Bittar
Author: G.R. Gobran
Author: Alberto Figoli
Author: National Research Council
Author: 
Author: Torald Hermann Sollmann
Author: Jean L. Bolognia
Author: Jan Wilschut