Author: Vasile V. Cosofret Publisher: CRC Press ISBN: 1351083945 Category : Science Languages : en Pages : 443
Book Description
A one-of-a-kind book discussing drug-membrane sensors in pharmaceutical analysis Pharmaceutical Applications of Membrane Sensors is the first book to deal with the theory of drug-membrane sensors, as well as applications of such devices in pharmaceutical analysis. The book contains three main parts. The three major sections of the book cover the design and principles of membrane drug sensors, the use of membrane sensors in the analysis of pharmaceuticals, and various aspects of drug release monitoring by membrane sensors. Detailed analytical methods for more than 400 organic pharmaceuticals assayed by membrane sensor techniques are presented. Pharmaceutical Applications of Membrane Sensors will be a valuable reference for specialists in analytical and pharmaceutical chemistry, electroanalytical chemistry, medicine, pharmaceutical sciences, and pharmacology.
Author: Annarosa Gugliuzza Publisher: John Wiley & Sons ISBN: 1119028639 Category : Science Languages : en Pages : 333
Book Description
This book addresses the reader to use synergistically the concepts of membranes and sensors materials. It contains insightful contributions from leading scientists working in both the fields. The focus is on the fabrication of smart membranes from sensor materials and related impact on many technologically sophisticated areas such as telemedicine, microfluidics, drug delivery targeting, (bio)separation, labs-on-a-chip, textiles, power storage and release, environment monitoring, agro-food safety, cosmetics, architecture, automotive and so on. This book covers various topics, including the choice of materials and techniques for assembling responsive membranes with ability to transport mass, energy and signals on demand; the reader will find through the book an extensive description of the best techniques used to monitor molecular scale events, which are regarded as responsible for the smartness of multifunctional objects and for the conversion of chemical signals into optical, electrical, thermal and mechanical responses. The reader is encouraged to use this cross-disciplinary discussion for his own research. Chemical, biological and physical concepts, expressed through the book, contribute to form a common language, which will allow the reader to discover causes for reflection and innovation, measuring how smart objects with desired properties can be tailored from exiting materials and used flexibly for different developed applications. Specifically: This book deals with materials smartness and suitable techniques to assemble and characterize them in sensor-like membranes. This book shows how ultra-smart functional devices can be accomplished by using traditional raw materials. This book describes particular key events, which control 'sense to react and adapt' mechanisms. The potential of sensor-like membranes in some key strategic fields is examined with particular emphasis on biomedicine, food and textiles markets. The benefits arising from the use of smart membranes are analysed in terms of life quality, safety, and innovation.
Author: Claus Hélix-Nielsen Publisher: Springer Science & Business Media ISBN: 9400721846 Category : Science Languages : en Pages : 303
Book Description
This book addresses the possibilities and challenges in mimicking biological membranes and creating membrane-based sensor and separation devices. Recent advances in developing biomimetic membranes for technological applications will be presented with focus on the use of integral membrane protein mediated transport for sensing and separation. It describes the fundamentals of biosensing as well as separation and shows how the two processes are working in a cooperative manner in biological systems. Biomimetics is a truly cross-disciplinary approach and this is exemplified using the process of forward osmosis will be presented as an illustration of how advances in membrane technology may be directly stimulated by an increased understanding of biological membrane transport. In the development of a biomimetic sensor/separation technology, both channels (ion and water channels) and carriers (transporters) are important. An ideal sensor/separation device requires the supporting biomimetic matrix to be virtually impermeable to anything but the solute in question. In practice, however, a biomimetic support matrix will generally have finite permeabilities to water, electrolytes, and non-electrolytes. These non-protein mediated membrane transport contributions will be presented and the implications for biomimetic device construction will be discussed. New developments in our understanding of the reciprocal coupling between the material properties of the biomimetic matrix and the embedded proteins will be presented and strategies for inducing biomimetic matrix stability will be discussed. Once reconstituted in its final host biomimetic matrix the protein stability also needs to be maintained and controlled. Beta-barrel proteins exemplified by the E. Coli outer membrane channels or small peptides are inherently more stable than alpha-helical bundle proteins which may require additional stabilizing modifications. The challenges associated with insertion and stabilization of alpha-helical bundle proteins including many carriers and ligand and voltage gated ion (and water) channels will be discussed and exemplified using the aquaporin protein. Many biomimetic membrane applications require that the final device can be used in the macroscopic realm. Thus a biomimetic separation device must have the ability to process hundred of liters of permeate in hours – effectively demanding square-meter size membranes. Scalability is a general issue for all nano-inspired technology developments and will be addressed here in the context biomimetic membrane array fabrication. Finally a robust working biomimetic device based on membrane transport must be encapsulated and protected yet allowing massive transport though the encapsulation material. This challenge will be discussed using microfluidic design strategies as examples of how to use microfluidic systems to create and encapsulate biomimetic membranes. The book provides an overview of what is known in the field, where additional research is needed, and where the field is heading.
Author: Vasile V. Cosofret Publisher: CRC Press ISBN: 1351092391 Category : Science Languages : en Pages : 507
Book Description
A one-of-a-kind book discussing drug-membrane sensors in pharmaceutical analysis Pharmaceutical Applications of Membrane Sensors is the first book to deal with the theory of drug-membrane sensors, as well as applications of such devices in pharmaceutical analysis. The book contains three main parts. The three major sections of the book cover the design and principles of membrane drug sensors, the use of membrane sensors in the analysis of pharmaceuticals, and various aspects of drug release monitoring by membrane sensors. Detailed analytical methods for more than 400 organic pharmaceuticals assayed by membrane sensor techniques are presented. Pharmaceutical Applications of Membrane Sensors will be a valuable reference for specialists in analytical and pharmaceutical chemistry, electroanalytical chemistry, medicine, pharmaceutical sciences, and pharmacology.
Author: Claus Hélix-Nielsen Publisher: Springer Science & Business Media ISBN: 9400721838 Category : Science Languages : en Pages : 303
Book Description
This book addresses the possibilities and challenges in mimicking biological membranes and creating membrane-based sensor and separation devices. Recent advances in developing biomimetic membranes for technological applications will be presented with focus on the use of integral membrane protein mediated transport for sensing and separation. It describes the fundamentals of biosensing as well as separation and shows how the two processes are working in a cooperative manner in biological systems. Biomimetics is a truly cross-disciplinary approach and this is exemplified using the process of forward osmosis will be presented as an illustration of how advances in membrane technology may be directly stimulated by an increased understanding of biological membrane transport. In the development of a biomimetic sensor/separation technology, both channels (ion and water channels) and carriers (transporters) are important. An ideal sensor/separation device requires the supporting biomimetic matrix to be virtually impermeable to anything but the solute in question. In practice, however, a biomimetic support matrix will generally have finite permeabilities to water, electrolytes, and non-electrolytes. These non-protein mediated membrane transport contributions will be presented and the implications for biomimetic device construction will be discussed. New developments in our understanding of the reciprocal coupling between the material properties of the biomimetic matrix and the embedded proteins will be presented and strategies for inducing biomimetic matrix stability will be discussed. Once reconstituted in its final host biomimetic matrix the protein stability also needs to be maintained and controlled. Beta-barrel proteins exemplified by the E. Coli outer membrane channels or small peptides are inherently more stable than alpha-helical bundle proteins which may require additional stabilizing modifications. The challenges associated with insertion and stabilization of alpha-helical bundle proteins including many carriers and ligand and voltage gated ion (and water) channels will be discussed and exemplified using the aquaporin protein. Many biomimetic membrane applications require that the final device can be used in the macroscopic realm. Thus a biomimetic separation device must have the ability to process hundred of liters of permeate in hours – effectively demanding square-meter size membranes. Scalability is a general issue for all nano-inspired technology developments and will be addressed here in the context biomimetic membrane array fabrication. Finally a robust working biomimetic device based on membrane transport must be encapsulated and protected yet allowing massive transport though the encapsulation material. This challenge will be discussed using microfluidic design strategies as examples of how to use microfluidic systems to create and encapsulate biomimetic membranes. The book provides an overview of what is known in the field, where additional research is needed, and where the field is heading.
Author: Sergey Yurish Publisher: Lulu.com ISBN: 8409030284 Category : Technology & Engineering Languages : en Pages : 560
Book Description
The Vol. 5 of this Book Series contains 22 chapters written by 79 contributors-experts from universities, research centres and industry from 15 countries: Australia, Canada, China, France, Germany, Italy, Malaysia, Mexico, Poland, Portugal, Russia, Slovenia, Spain, Ukraine and USA. This volume contains information at the cutting edge of sensor research and related topics from the following three areas: Physical Sensors, Sensor Networks and Remote Sensing. Coverage includes current developments in various sensors, sensor instrumentation and applications. In order to offer a fast and easy reading of each topic, every chapter in this volume is independent and self-contained.With the unique combination of information in this volume, the 'Advances in Sensors: Reviews' Book Series will be of value for scientists and engineers in industry and at universities, to sensors developers, distributors, and end users.
Author: Claus Hélix-Nielsen Publisher: Springer ISBN: 9789400721852 Category : Science Languages : en Pages : 292
Book Description
This book addresses the possibilities and challenges in mimicking biological membranes and creating membrane-based sensor and separation devices. Recent advances in developing biomimetic membranes for technological applications will be presented with focus on the use of integral membrane protein mediated transport for sensing and separation. It describes the fundamentals of biosensing as well as separation and shows how the two processes are working in a cooperative manner in biological systems. Biomimetics is a truly cross-disciplinary approach and this is exemplified using the process of forward osmosis will be presented as an illustration of how advances in membrane technology may be directly stimulated by an increased understanding of biological membrane transport. In the development of a biomimetic sensor/separation technology, both channels (ion and water channels) and carriers (transporters) are important. An ideal sensor/separation device requires the supporting biomimetic matrix to be virtually impermeable to anything but the solute in question. In practice, however, a biomimetic support matrix will generally have finite permeabilities to water, electrolytes, and non-electrolytes. These non-protein mediated membrane transport contributions will be presented and the implications for biomimetic device construction will be discussed. New developments in our understanding of the reciprocal coupling between the material properties of the biomimetic matrix and the embedded proteins will be presented and strategies for inducing biomimetic matrix stability will be discussed. Once reconstituted in its final host biomimetic matrix the protein stability also needs to be maintained and controlled. Beta-barrel proteins exemplified by the E. Coli outer membrane channels or small peptides are inherently more stable than alpha-helical bundle proteins which may require additional stabilizing modifications. The challenges associated with insertion and stabilization of alpha-helical bundle proteins including many carriers and ligand and voltage gated ion (and water) channels will be discussed and exemplified using the aquaporin protein. Many biomimetic membrane applications require that the final device can be used in the macroscopic realm. Thus a biomimetic separation device must have the ability to process hundred of liters of permeate in hours – effectively demanding square-meter size membranes. Scalability is a general issue for all nano-inspired technology developments and will be addressed here in the context biomimetic membrane array fabrication. Finally a robust working biomimetic device based on membrane transport must be encapsulated and protected yet allowing massive transport though the encapsulation material. This challenge will be discussed using microfluidic design strategies as examples of how to use microfluidic systems to create and encapsulate biomimetic membranes. The book provides an overview of what is known in the field, where additional research is needed, and where the field is heading.
Author: Andrzej Lewenstam Publisher: Mdpi AG ISBN: 9783036510705 Category : Science Languages : en Pages : 154
Book Description
Ion-sensitive membrane-based sensors and ionic processes in bio-membranes are the focus of this book. The chapters are carefully chosen to characterize essential research trends, applications, and perspectives. They include solid contact ion-selective and reference electrodes and their electroanalytical behavior in zero and nonzero-current modes, planar and miniaturized multielectrode platforms, ion monitoring in extreme sports, and transmembrane transport through living endothelial cells to find the volume. This book is crowned by the consideration of a yet unexplored ion status in a mitochondrial matrix
Author: Vasile V. Cosofret
Author: Annarosa Gugliuzza
Author: Claus Hélix-Nielsen
Author: Vasile V. Cosofret
Author: Claus Hélix-Nielsen
Author: Shuichi Suzuki
Author: Sergey Yurish
Author: Miguel A. R. B. Castanho
Author: Claus Hélix-Nielsen
Author: Andrzej Lewenstam