Author: A. Wagoner Johnson Publisher: Springer Science & Business Media ISBN: 1441980830 Category : Technology & Engineering Languages : en Pages : 329
Book Description
Mechanobiology of Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediate cell behavior. Studies of cell-matrix interactions rely on integrating engineering, (molecular and cellular) biology, and imaging disciplines. Recent advances in the field have begun to unravel our understanding of how cells gather information from their surrounding environment, and how they interrogate such information during the cell fate decision making process. Topics include adhesive and integrin-ligand interactions; extracellular influences on cell biology and behavior; cooperative mechanisms of cell-cell and cell-matrix interactions; the mechanobiology of pathological processes; (multi-scale) modeling approaches to describe the complexity or cell-matrix interactions; and quantitative methods required for such experimental and modeling studies.
Author: Christopher R. Jacobs Publisher: Garland Science ISBN: 1135042659 Category : Medical Languages : en Pages : 350
Book Description
Introduction to Cell Mechanics and Mechanobiology is designed for a one-semester course in the mechanics of the cell offered to advanced undergraduate and graduate students in biomedical engineering, bioengineering, and mechanical engineering. It teaches a quantitative understanding of the way cells detect, modify, and respond to the physical prope
Author: Stefaan Verbruggen Publisher: Academic Press ISBN: 0128129530 Category : Medical Languages : en Pages : 530
Book Description
Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. - Provides an essential digest of primary research from many fields and disciplines in one convenient volume - Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives - Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science
Author: Corinne Nardin Publisher: John Wiley & Sons ISBN: 3527810994 Category : Technology & Engineering Languages : en Pages : 288
Book Description
Biological Soft Matter Explore a comprehensive, one-stop reference on biological soft matter written and edited by leading voices in the field Biological Soft Matter: Fundamentals, Properties and Applications delivers a unique and indispensable compilation of up-to-date knowledge and material on biological soft matter. The book presents a thorough overview about biological soft matter, beginning with different substance classes, including proteins, nucleic acids, lipids, and polysaccharides. It goes on to describe a variety of superstructures and aggregated and how they are formed by self-assembly processes like protein folding or crystallization. The distinguished editors have included materials with a special emphasis on macromolecular assembly, including how it applies to lipid membranes, and proteins fibrillization. Biological Soft Matter is a crucial resource for anyone working in the field, compiling information about all important substance classes and their respective roles in forming superstructures. The book is ideal for beginners and experts alike and makes the perfect guide for chemists, physicists, and life scientists with an interest in the area. Readers will also benefit from the inclusion of: An introduction to DNA nano-engineering and DNA-driven nanoparticle assembly Explorations of polysaccharides and glycoproteins, engineered biopolymers, and engineered hydrogels Discussions of macromolecular assemblies, including liquid membranes and small molecule inhibitors for amyloid aggregation A treatment of inorganic nanomaterials as promoters and inhibitors of amyloid fibril formation An examination of a wide variety of natural and artificial polymers Perfect for materials scientists, biochemists, polymer chemists, and protein chemists, Biological Soft Matter: Fundamentals, Properties and Applications will also earn a place in the libraries of biophysicists and physical chemists seeking a one-stop reference summarizing the rapidly evolving topic of biological soft matter.
Author: Hiroyuki Abe Publisher: Springer Science & Business Media ISBN: 4431658629 Category : Technology & Engineering Languages : en Pages : 443
Book Description
A research project entitled Biomechanics of Structure and Function of Living Cells, Tissues, and Organs was launched in Japan in 1992. This data book presents the original, up-to-date information resulting from the research project, supplemented by some of the important basic data published previously. The aim of collecting the information is to offer accurate and useful data on the mechanical properties of living materials to biomechanical scientists, biomedical engineers, medical scientists, and clinicians. The data are presented in graphs and tables (one type of data per page) arranged in an easily accessible manner, along with details of the origin of the material and the experimental method. Together with its two companion volumes, Biomechanics: Functional Adaptation and Remodeling and Computational Biomechanics, the Data Book on Mechanical Properties of Living Cells, Tissues, and Organs is a timely and valuable contribution to the rapidly growing field of biomechanics.
Author: Yanhang Zhang Publisher: ISBN: 9783030201838 Category : Biomedical engineering Languages : en Pages : 392
Book Description
This book describes the current state of knowledge in the field of multi-scale ECM mechanics and mechanobiology with a focus on experimental and modelling studies in biomechanical characterization, advanced optical microscopy and imaging, as well as computational modeling. This book also discusses the scale dependency of ECM mechanics, translation of mechanical forces from tissue to cellular level, and advances and challenges in improving our understanding of cellular mechanotransduction in the context of living tissues and organisms.
Author: Glen L. Niebur Publisher: Elsevier ISBN: 0128179325 Category : Science Languages : en Pages : 256
Book Description
Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. - Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli - Provides a review of diseases with known or purported mechanobiological underpinnings - Includes the role of mechanobiology in tissue engineering and regenerative medicine - Covers experimental methods to capture mechanobiological phenomena
Author: David H. Boal Publisher: Cambridge University Press ISBN: 0521113768 Category : Science Languages : en Pages : 623
Book Description
New edition exploring the mechanical features of biological cells for advanced undergraduate and graduate students in physics and biomedical engineering.
Author: Roland Kaunas Publisher: CRC Press ISBN: 1466553820 Category : Medical Languages : en Pages : 370
Book Description
Explores a Range of Multiscale Biomechanics/Mechanobiology ConceptsCell and Matrix Mechanics presents cutting-edge research at the molecular, cellular, and tissue levels in the field of cell mechanics. This book involves key experts in the field, and covers crucial areas of cell and tissue mechanics, with an emphasis on the roles of mechanical forc
Author: Shu Chien Publisher: Springer ISBN: 9781493956159 Category : Medical Languages : en Pages : 0
Book Description
This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.
Author: A. Wagoner Johnson
Author: Christopher R. Jacobs
Author: Stefaan Verbruggen
Author: Corinne Nardin
Author: Hiroyuki Abe
Author: Yanhang Zhang
Author: Glen L. Niebur
Author: David H. Boal
Author: Roland Kaunas
Author: Shu Chien