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Author: E. Abraham Publisher: Springer Science & Business Media ISBN: 9783540301585 Category : Medical Languages : en Pages : 476
Book Description
There have been tremendous advances in understanding the cellular mechanisms involved in sepsis and contributing to the development of multiple organ dysfunction and mortality in this setting. The chapters in this book provide up-to-date insights into important pathways that are initiated by sepsis.
Author: E. Abraham Publisher: Springer Science & Business Media ISBN: 9783540301585 Category : Medical Languages : en Pages : 476
Book Description
There have been tremendous advances in understanding the cellular mechanisms involved in sepsis and contributing to the development of multiple organ dysfunction and mortality in this setting. The chapters in this book provide up-to-date insights into important pathways that are initiated by sepsis.
Author: Timothy W. Evans Publisher: Springer Science & Business Media ISBN: 3642561071 Category : Medical Languages : en Pages : 434
Book Description
The pathophysiology of sepsis can be regarded as a series of steps, beginning with the invasion of normally sterile tissue by microbes and the elaboration of various pro-inflammatory mediators. The final common pathway is often the development of the multiple organ dysfunction syndrome (MODS). Whereas a great deal has been learned during the past quarter century about the inflammatory processes associated with sepsis (and other related conditions, such as ischemia/reperfusion injury), our understanding is far less developed with respect to the pathophysiological events that lead to organ dysfunction under these conditions. Nevertheless, efforts by both clinical and laboratory scientists are leading to new knowledge in this area. The chapters in this volume provide a state-of-the-art overview of many aspects of the pathophysiology of organ dysfunction in critical illness.
Author: Robert Fitridge Publisher: University of Adelaide Press ISBN: 1922064009 Category : Medical Languages : en Pages : 589
Book Description
New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Author: Fang Gao Smith Publisher: Cambridge University Press ISBN: 1139489682 Category : Medical Languages : en Pages : 409
Book Description
The critical care unit manages patients with a vast range of disease and injuries affecting every organ system. The unit can initially be a daunting environment, with complex monitoring equipment producing large volumes of clinical data. Core Topics in Critical Care Medicine is a practical, comprehensive, introductory-level text for any clinician in their first few months in the critical care unit. It guides clinicians in both the initial assessment and the clinical management of all CCU patients, demystifying the critical care unit and providing key knowledge in a concise and accessible manner. The full spectrum of disorders likely to be encountered in critical care are discussed, with additional chapters on transfer and admission, imaging in the CCU, structure and organisation of the unit, and ethical and legal issues. Written by Critical Care experts, Core Topics in Critical Care Medicine provides comprehensive, concise and easily accessible information for all trainees.
Author: Jordi Rello Publisher: Springer Science & Business Media ISBN: 3540344063 Category : Medical Languages : en Pages : 630
Book Description
Critical care practitioners are often the initial providers of care to seriously ill patients with infections. This book provides clinicians practicing in the intensive care unit with a reference to help guide their care of infected patients. It brings together a group of international authors to address important topics related to infectious diseases for the critical care practitioner.
Author: Webb Publisher: Oxford University Press ISBN: 0198855435 Category : Medical Languages : en Pages : 1961
Book Description
Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.
Author: Robert D. Stevens Publisher: Academic ISBN: 0199653461 Category : Medical Languages : en Pages : 649
Book Description
Surviving critical illness is not always the happy ending that we imagine for patients. Intensive care unit (ICU) teams have traditionally focused on short term goals such as stabilizing or reversing organ system dysfunction, with little understanding of what became of patients once they left the ICU. However, research conducted in recent years has demonstrated that many ICU survivors can suffer from ill health and mental health issues for months or years to follow. The Textbook of Post-ICU Medicine: The Legacy of Critical Care identifies the long term outcomes of ICU and the steps that can be taken to improve patients' health and wellbeing. Describing the major clinical syndromes affecting ICU survivors, the book delineates established or postulated biological mechanisms of the post-acute recovery process, and discusses strategies for treatment and rehabilitation to promote recovery in the ICU and in the long term. The book serves as a unique reference for general practitioners, internists and nurses caring for long term ICU survivors as well as specialists in intensive care medicine, neurology, psychiatry, and rehabilitation medicine.
Author: Lawrence H. Lash Publisher: Elsevier ISBN: 1483218619 Category : Science Languages : en Pages : 527
Book Description
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Author: Günther Schlag Publisher: Springer Science & Business Media ISBN: 3642767362 Category : Medical Languages : en Pages : 1180
Book Description
In this book current knowledge of the pathophysiology of shock, sepsis and multi organ failure is presented. The rapid progress which has been made and the results achieved in intensive care medicine are based on sound basic research, which is duly reflected in these chapters. Multiorgan failure is the foremost cause of postoperative and posttraumatic death and many complex mechanisms are involved. Only with a good foundation of basic research can abnormalities in the physiological, biochemical, and morphological course of shock be recognized and the necessary conclusions for treatment drawn. Therapy must proceed from profound knowledge of the multi variant physiological events in order to influence shock, sepsis and organ failure. Although numerous possibilities for therapy have arisen from pharmaceutical research in recent years, they are beyond the scope of this book and are not discussed here. To gain a better understanding of the pathophysiological events it was necessary to examine and to describe different models that simulate and reproduce these events. Here we describe the causative agents (shock) and the consequences (sepsis, organ failure) in two main sections, divided on the basis of their pathophysiology.
Author: E. Abraham
Author: E. Abraham
Author: Timothy W. Evans
Author: Robert Fitridge
Author: Fang Gao Smith
Author: René Holzheimer
Author: Jordi Rello
Author: Webb
Author: Robert D. Stevens
Author: Lawrence H. Lash
Author: Günther Schlag