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Author: Gideon Koren Publisher: Marcel Dekker ISBN: Category : Medical Languages : en Pages : 856
Book Description
For health professionals who are asked by women and their families to provide answers on potential reproductive effects of xenobiotics and radiation, this volume presents the approaches and clinical tools developed by the multidisciplinary team at the Motherisk Clinic in Toronto to inform, counsel, and follow up pregnant women exposed to drugs, chemicals, or radiation in pregnancy. This revised and expanded edition adds several novel aspects, such as the maternal-fetal toxicology of medicinal plants, developmental risk assessment, and biological markers of intrauterine exposure to drugs of abuse. This edition also includes clinical cases at the beginning of most chapters, with answers at the end. Annotation c. by Book News, Inc., Portland, Or.
Author: Gideon Koren Publisher: Marcel Dekker ISBN: Category : Medical Languages : en Pages : 856
Book Description
For health professionals who are asked by women and their families to provide answers on potential reproductive effects of xenobiotics and radiation, this volume presents the approaches and clinical tools developed by the multidisciplinary team at the Motherisk Clinic in Toronto to inform, counsel, and follow up pregnant women exposed to drugs, chemicals, or radiation in pregnancy. This revised and expanded edition adds several novel aspects, such as the maternal-fetal toxicology of medicinal plants, developmental risk assessment, and biological markers of intrauterine exposure to drugs of abuse. This edition also includes clinical cases at the beginning of most chapters, with answers at the end. Annotation c. by Book News, Inc., Portland, Or.
Author: Ronald D. Hood Publisher: CRC Press ISBN: 1420040545 Category : Medical Languages : en Pages : 1164
Book Description
Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers e
Author: National Research Council (U.S.). Subcommittee on Reproductive and Neurodevelopmental Toxicology Publisher: Routledge ISBN: Category : Medical Languages : en Pages : 424
Author: CaroleAKimmel Publisher: CRC Press ISBN: 9780781701372 Category : Medical Languages : en Pages : 502
Book Description
The Second Edition of this highly regarded work provides a state-of-the-art review of developmental toxicology from basic science, clinical, epidemiological, and regulatory perspectives. This new edition highlights the latest approaches to understanding the mechanisms of developmental toxicity, testing pharmaceutical and environmental agents, and interpreting developmental toxicity data.; The contributors demonstrate how new information on molecular embryology and cell biology is being applied to problems in developmental toxicology. Chapters describe the effects of toxic exposure on the functional development of various organs, examine the relationship between maternal and developmental toxicity, and discuss current techniques for studying chemical disposition, metabolism, and placental transfer. Close attention is given to the use of mathematical and statistical techniques in data interpretation, as well as to the regulatory aspects of testing and risk assessment. Other chapters focus on pre- and post conceptional clinical care and on genetic factors in clinical developmental toxicology.
Author: Donald Mattison Publisher: Academic Press ISBN: 0123860075 Category : Medical Languages : en Pages : 496
Book Description
Clinical Pharmacology During Pregnancy is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals directly involved in the care of women during pregnancy. This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems, as well as essential content on dosing and efficacy. Written in a clear and practical manner, this reference provides easily accessible information and clinical guidance on how best to treat women with medications during pregnancy.
Author: National Research Council Publisher: National Academies Press ISBN: 0309036879 Category : Nature Languages : en Pages : 476
Book Description
The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.
Author: K.S. Khera Publisher: Springer Science & Business Media ISBN: 1468463799 Category : Medical Languages : en Pages : 142
Book Description
The International Life Sciences Institute (!LSI) is a scientific foundation that addresses critical health and safety issues of national and international con cern. ILSI promotes international cooperation by providing the mechanism for scientists from government, industry, and universities to work together on cooperative programs to generate and disseminate scientific data. The mem bers and trustees of the institute believe that questions regarding health and safety are best resolved when scientists can examine and discuss issues as an independent body separate from the political pressures of individual countries and the economic concerns of individual companies. Frequently, meaningful assessment of the risk of a test substance is hindered by the inherent inconsistencies in the system. The development and refine ment of methods and systems to evaluate the safety of chemicals have evolved in a rapid and largely unplanned fashion. Attempts to improve the system have mainly been directed toward broad general concerns, with little attention being given to specific problems or issues. A failure to resolve these problems has frequently resulted in increased testing costs and complications in the assessment and extrapolation of the results to humans. Publicity surrounding toxicologic issues makes it difficult for governments to deal effectively with these problems. In response to these difficulties, ILSI has assembled highly qualified and renowned scientists from research institutes, universities, government, and industry with relevant scientific knowledge and expertise regarding the issues that complicate risk assessment procedures.
Author: Ali S. Faqi Publisher: Humana ISBN: 9781493984169 Category : Medical Languages : en Pages : 314
Book Description
This meticulous volume covers metabolism and drug-drug interactions during pregnancy, critical periods of developmental toxicology, in vivo and alternative methods to assess potential developmental toxicity for drugs and chemicals, and effects of chemicals on testes and mammary glands. Evaluation of developmental and reproductive toxicology endpoints is an integral part of the safety assessment process for compounds with potential use in women of childbearing age or females that might be exposed during pregnancy as well as men of reproductive potential. The in vivo assessments included here are guideline-driven and are required for submissions for product approval. Written for the Methods in Pharmacology and Toxicology series, this collection includes the kind of detailed implementation advice necessary for success in the lab. Authoritative and practical, Developmental and Reproductive Toxicology is an ideal resource for researchers working in this vital field of study./div
Author: B. V. Rama Sastry Publisher: CRC Press ISBN: 9781439805527 Category : Medical Languages : en Pages : 312
Book Description
Placental Toxicology examines placental transfer and toxicology of drugs and environmental agents to placenta, as well as to fetus. For the first time in a single volume, placental and fetal consequences of exposure of pregnant women to drugs, environmental chemicals, and infections, such as HIV, are discussed. Topics include: The art of in
Author: Gideon Koren
Author: Gideon Koren
Author: Gideon Koren
Author: Ronald D. Hood
Author: National Research Council (U.S.). Subcommittee on Reproductive and Neurodevelopmental Toxicology
Author: CaroleAKimmel
Author: Donald Mattison
Author: National Research Council
Author: K.S. Khera
Author: Ali S. Faqi
Author: B. V. Rama Sastry