Genetic Dissection of Neural Circuits and Behavior PDF Download

Author: Stephen F. Goodwin
Publisher:
ISBN: 9780123748362
Category : Medical
Languages : en
Pages : 199

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Book Description
The latest volume in the widely-praised Advances in Genetics series.

Author: Mohan Kancharla
Publisher: Notion Press
ISBN: 1637816383
Category : Business & Economics
Languages : en
Pages : 242

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Book Description
Consulting is an Art, not a Science – Design on the other hand is beyond Art; it’s about pragmatic compromise, not perfection. Design Thinking in literal terms means thinking as a designer would. Design Thinking as a method is empirical in the sense that it is both experimental and experiential. However, like all methods, it’s not what it is but what you do with it that counts! Design Thinking is an approach to innovation that is powerful, effective and broadly accessible, which can be integrated into all aspects of products, services, business and society. Design Thinking in Consulting is structured in three parts along the lines of Roger Martin’s ‘Knowledge Funnel’ moving from Mystery to Heuristic to Algorithm. Part I | Consulting Overview of Consulting with a specific focus on Consulting Spectrum and Consulting Cycle for the purpose of this book – The Mystery. Part II | Design Thinking Introduction to Design Thinking, the various schools of thought, approaches, tools and techniques analyzed and articulated as a matrix of Principles vs Practices for the purpose of this book – The Heuristic. Part III | Design Thinking in Consulting In separate chapters for each of the Consulting Phases, the above Design Thinking Principles and Practices are evaluated to be fit for purpose and further extrapolated to relevant segments of the Consulting Spectrum for the purpose of this book – The Algorithm.

Author: Josh Dubnau
Publisher: Cambridge University Press
ISBN: 1107009030
Category : Medical
Languages : en
Pages : 309

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Book Description
A comprehensive portrayal of the behaviour genetics of the fruit fly (Drosophila melanogaster) and the methods used in these studies.

Author: Arzu Çelik
Publisher: Springer
ISBN: 3319573632
Category : Medical
Languages : en
Pages : 517

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Book Description
This book offers representative examples from fly and mouse models to illustrate the ongoing success of the synergistic, state-of-the-art strategy, focusing on the ways it enhances our understanding of sensory processing. The authors focus on sensory systems (vision, olfaction), which are particularly powerful models for probing the development, connectivity, and function of neural circuits, to answer this question: How do individual nerve cells functionally cooperate to guide behavioral responses? Two genetically tractable species, mice and flies, together significantly further our understanding of these processes. Current efforts focus on integrating knowledge gained from three interrelated fields of research: (1) understanding how the fates of different cell types are specified during development, (2) revealing the synaptic connections between identified cell types (“connectomics”) using high-resolution three-dimensional circuit anatomy, and (3) causal testing of how iden tified circuit elements contribute to visual perception and behavior.

Author: Gerhard Martin Technau
Publisher: Springer Science & Business Media
ISBN: 0387782613
Category : Medical
Languages : en
Pages : 173

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Book Description
The fruitfly Drosophila melanogaster is an ideal model system to study processes of the central nervous system This book provides an overview of some major facets of recent research on Drosophila brain development.

Author: Nicholas James Strausfeld
Publisher: Harvard University Press
ISBN: 0674046331
Category : Science
Languages : en
Pages : 849

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Book Description
In The Descent of Man, Charles Darwin proposed that an ant’s brain, no larger than a pin’s head, must be sophisticated to accomplish all that it does. Yet today many people still find it surprising that insects and other arthropods show behaviors that are much more complex than innate reflexes. They are products of versatile brains which, in a sense, think. Fascinating in their own right, arthropods provide fundamental insights into how brains process and organize sensory information to produce learning, strategizing, cooperation, and sociality. Nicholas Strausfeld elucidates the evolution of this knowledge, beginning with nineteenth-century debates about how similar arthropod brains were to vertebrate brains. This exchange, he shows, had a profound and far-reaching impact on attitudes toward evolution and animal origins. Many renowned scientists, including Sigmund Freud, cut their professional teeth studying arthropod nervous systems. The greatest neuroanatomist of them all, Santiago Ramón y Cajal—founder of the neuron doctrine—was awed by similarities between insect and mammalian brains. Writing in a style that will appeal to a broad readership, Strausfeld weaves anatomical observations with evidence from molecular biology, neuroethology, cladistics, and the fossil record to explore the neurobiology of the largest phylum on earth—and one that is crucial to the well-being of our planet. Highly informative and richly illustrated, Arthropod Brains offers an original synthesis drawing on many fields, and a comprehensive reference that will serve biologists for years to come.

Author: Peter Sterling
Publisher: MIT Press
ISBN: 0262028700
Category : Education
Languages : en
Pages : 567

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Book Description
Neuroscience research has exploded, with more than fifty thousand neuroscientists applying increasingly advanced methods. A mountain of new facts and mechanisms has emerged. And yet a principled framework to organize this knowledge has been missing. In this book, Peter Sterling and Simon Laughlin, two leading neuroscientists, strive to fill this gap, outlining a set of organizing principles to explain the whys of neural design that allow the brain to compute so efficiently. Setting out to "reverse engineer" the brain -- disassembling it to understand it -- Sterling and Laughlin first consider why an animal should need a brain, tracing computational abilities from bacterium to protozoan to worm. They examine bigger brains and the advantages of "anticipatory regulation"; identify constraints on neural design and the need to "nanofy"; and demonstrate the routes to efficiency in an integrated molecular system, phototransduction. They show that the principles of neural design at finer scales and lower levels apply at larger scales and higher levels; describe neural wiring efficiency; and discuss learning as a principle of biological design that includes "save only what is needed." Sterling and Laughlin avoid speculation about how the brain might work and endeavor to make sense of what is already known. Their distinctive contribution is to gather a coherent set of basic rules and exemplify them across spatial and functional scales.

Author: Carla Mucignat-Caretta
Publisher: CRC Press
ISBN: 1466553413
Category : Medical
Languages : en
Pages : 614

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Book Description
Intraspecific communication involves the activation of chemoreceptors and subsequent activation of different central areas that coordinate the responses of the entire organism—ranging from behavioral modification to modulation of hormones release. Animals emit intraspecific chemical signals, often referred to as pheromones, to advertise their presence to members of the same species and to regulate interactions aimed at establishing and regulating social and reproductive bonds. In the last two decades, scientists have developed a greater understanding of the neural processing of these chemical signals. Neurobiology of Chemical Communication explores the role of the chemical senses in mediating intraspecific communication. Providing an up-to-date outline of the most recent advances in the field, it presents data from laboratory and wild species, ranging from invertebrates to vertebrates, from insects to humans. The book examines the structure, anatomy, electrophysiology, and molecular biology of pheromones. It discusses how chemical signals work on different mammalian and non-mammalian species and includes chapters on insects, Drosophila, honey bees, amphibians, mice, tigers, and cattle. It also explores the controversial topic of human pheromones. An essential reference for students and researchers in the field of pheromones, this is also an ideal resource for those working on behavioral phenotyping of animal models and persons interested in the biology/ecology of wild and domestic species.

Author:
Publisher: Academic Press
ISBN: 0080951155
Category : Science
Languages : en
Pages : 218

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Book Description
Genes interact with the environment, experience, and biology of the brain to shape an animal's behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity. - Explores the latest topics in neural circuits and behavior research in zebrafish, drosophila, C.elegans, and mouse models - Includes methods for testing with ethical, legal, and social implications - Critically analyzes future prospects

Author: Stanley Heinze
Publisher: Frontiers Media SA
ISBN: 2889455785
Category :
Languages : en
Pages : 179

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