Management of Metastatic Liver Tumors, an Issue of Surgical Oncology Clinics of North America, Volume 30-1 PDF Download

Author: Michael D'Angelica
Publisher: Elsevier
ISBN: 9780323764490
Category : Medical
Languages : en
Pages : 240

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Book Description
This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Michael I. D'Angelica, is devoted to Management of Metastatic Liver Tumors. Dr. D'Angelica has assembled expert authors to review the following topics: Surgical management of liver metastases of colorectal cancer; Surgical management of liver metastases of breast cancer; Surgical management of liver metastases of neuroendocrine tumors; Surgical management of liver metastases of sarcoma (including GIST); Surgical management of liver metastases of gynecologic cancers; Surgical management of liver metastases of genitourinary cancers; Surgical management of liver metastases of uveal and dermal melanoma; Is there a role for locoregional therapies for non-colorectal GI malignancies?; Intra-arterial chemotherapy for liver metastases; External beam radiation for liver metastases; Isolated hepatic perfusion for liver metastases; Debate: Improvements in systemic therapies for liver metastases will soon render locoregional treatments obsolete; Debate: Improvements in systemic therapies for liver metastases will increase the role of locoregional treatments; and more!

Author: Michael D'Angelica
Publisher: Elsevier Health Sciences
ISBN: 0323764509
Category : Medical
Languages : en
Pages : 241

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Book Description
This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Michael I. D'Angelica, is devoted to Management of Metastatic Liver Tumors. Dr. D'Angelica has assembled expert authors to review the following topics: Surgical management of liver metastases of colorectal cancer; Surgical management of liver metastases of breast cancer; Surgical management of liver metastases of neuroendocrine tumors; Surgical management of liver metastases of sarcoma (including GIST); Surgical management of liver metastases of gynecologic cancers; Surgical management of liver metastases of genitourinary cancers; Surgical management of liver metastases of uveal and dermal melanoma; Is there a role for locoregional therapies for non-colorectal GI malignancies?; Intra-arterial chemotherapy for liver metastases; External beam radiation for liver metastases; Isolated hepatic perfusion for liver metastases; Debate: Improvements in systemic therapies for liver metastases will soon render locoregional treatments obsolete; Debate: Improvements in systemic therapies for liver metastases will increase the role of locoregional treatments; and more!

Author: Michael D'Angelica
Publisher:
ISBN: 9780443346798
Category : Medical
Languages : en
Pages : 0

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Book Description
In this issue of Hematology/Oncology Clinics, guest editor Dr. Michael D’Angelica brings his considerable expertise to the topic of Management of Metastatic Liver Tumors. Top experts cover key topics such as surgical management of colorectal cancer liver metastases, breast cancer liver metastasis, and neuroendocrine tumor liver metastases; surgical management of sarcoma metastatic to liver; surgical management of gynecologic cancers; and many more. Contains 13 relevant, practice-oriented topics including liver directed locoregional therapies; intraarterial chemotherapy for liver metastases; external beam radiation therapy for liver metastases; hepatic perfusion for diffuse metastatic cancer to the liver: open and percutaneous techniques; and more. Provides in-depth clinical reviews on management of metastatic liver tumors, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author: Lawrence Wagman
Publisher: Elsevier Health Sciences
ISBN: 0323342043
Category : Medical
Languages : en
Pages : 233

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Book Description
This issue of Surgical Oncology Clinics of North America, edited by Dr. Lawrence Wagman, is devoted to Hepatocellular Cancer, Cholangiocarcinoma, and Metastatic Tumors of the Liver. Articles in this issue include: Epidemiology of Hepatomas; Risk Modeling: disease prevalence, outcome from treatment; Imaging; Resection techniques; Ablation techniques; Complications of interventions; Trans-arterial chemo-embolization (TACE); Continuous hepatic artery infusion (CHAI); Selective interstitial radiation therapy (SIRT) and External beam radiation therapy (EBRT); Systemic chemotherapy of HCC and Cholangiocarcinoma; and Systemic chemotherapy and CRC metastases.

Author: T. Clark Gamblin
Publisher: Elsevier Health Sciences
ISBN: 0323708838
Category : Medical
Languages : en
Pages :

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Book Description
This issue of Surgical Oncology Clinics of North America focuses on Biliary Tract and Primary Liver Tumors and is edited by Dr. T. Clark Gamblin. Articles will include: Biliary Tract and Primary Liver Tumors; Biliary Tract and Primary Liver Tumors: Who, What and Why?; Imaging Updates for Biliary Tract or Primary Liver Tumors; Endoscopic and Percutaneous Approaches to Treat of Biliary Tract and Primary Liver Tumors: Controversies and Advances; Intrahepatic Cholangiocarcinoma: Strategies and Options; Surgical Considerations of Hilar Cholangiocarcinoma; Gall Bladder Cancer: Managing the Incidental Diagnosis; Approaches and Outcomes to Distal Cholangiocarcinoma; Evolving Surgical Options of Hepatocellular Carcinoma; Staging of Biliary and Primary Liver Tumors: Current Reccomendations and Workup; Systemic and Targeted Therapy for Biliary Tract Tumors and Primary Liver Tumors; Regional Chemotherapy for Biliary Tract and Primary Liver Cancer; Role of Radioembolization for Biliary Tract and Primary Liver Cancer; Inoperable Biliary Tract and Primary Liver Tumors: Palliative Treatment Options; Expanding the Surgical Pool for Hepatic Resection to Treat Biliary and Primary Liver Tumors; and more!

Author: Adam C. Yopp
Publisher: Elsevier Health Sciences
ISBN: 044318397X
Category : Medical
Languages : en
Pages : 217

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Book Description
In this issue of Surgical Oncology Clinics, guest editors Drs. Adam Yopp and Maria B. Majella Doyle bring their considerable expertise to the topic of Hepatocellular Carcinoma. Top experts in the field explore promising recent advances in the treatment of all stages of hepatocellular carcinoma (HCC), neoadjuvant or downstaging therapy, the role of LI-RADS in hepatocellular carcinoma, surveillance of hepatocellular carcinoma, liver transplantation, and more. Contains 13 relevant, practice-oriented topics, including the changing epidemiology of HCC within the US and worldwide; HCC surveillance: evidence-based tailored approach; surgical resection outside early stage HCC; minimally invasive techniques for HCC resection; overview of current HCC staging systems: is there an optimal system?; and more. Provides in-depth clinical reviews on hepatocellular carcinoma, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author: Timothy M Pawlik
Publisher: Elsevier Health Sciences
ISBN: 0323290191
Category : Medical
Languages : en
Pages : 257

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Book Description
This issue of Surgical Oncology Clinics of North America is devoted to "Biliary Tract and Primary Liver Tumors" and is edited by Timothy Pawlik, MD, of the Johns Hopkins Hospital in Baltimore. Expert authors in this issue review this topic in articles such as: Epidemiology and Risk Factors of Biliary Tract Tumors and Primary Liver Tumors; Imaging of the Patient with a Biliary Tract or Primary Liver Tumor; Percutaneous and Endoscopic Approaches to Biliary Tract Tumors and Primary Liver Tumors; Intrahepatic Cholangiocarcinoma; Hilar Cholangiocarcinoma; Distal Cholangiocarcinoma; Hepatocellular Carcinoma; Staging of Biliary Tract and Primary Liver Tumors; Intra-arterial Therapies: Primary Liver Tumors; Radiotherapy: Primary Liver Tumors; Systemic and Targeted Therapy; and Palliation: Treating Patients with Inoperable Biliary Tract and Primary Liver Tumors.

Author: Adam C. Yopp
Publisher:
ISBN: 9780443183966
Category : Medical
Languages : en
Pages : 0

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Book Description
In this issue of Surgical Oncology Clinics, guest editors Drs. Adam Yopp and Maria B. Majella Doyle bring their considerable expertise to the topic of Hepatocellular Carcinoma. Top experts in the field explore promising recent advances in the treatment of all stages of hepatocellular carcinoma (HCC), neoadjuvant or downstaging therapy, the role of LI-RADS in hepatocellular carcinoma, surveillance of hepatocellular carcinoma, liver transplantation, and more. Contains 13 relevant, practice-oriented topics, including the changing epidemiology of HCC within the US and worldwide; HCC surveillance: evidence-based tailored approach; surgical resection outside early stage HCC; minimally invasive techniques for HCC resection; overview of current HCC staging systems: is there an optimal system?; and more. Provides in-depth clinical reviews on hepatocellular carcinoma, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author: Pnina Brodt
Publisher: Springer Science & Business Media
ISBN: 9400702922
Category : Medical
Languages : en
Pages : 447

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Book Description
Liver metastases are a frequent and often fatal occurrence in cancer patients, particularly those with malignancies of the gastrointestinal (GI) tract. While recent improvements in surgical techniques and a more aggressive approach to resection of liver metastases have improved long term survival for some patients, most patients with hepatic metastases still succumb to their disease. To improve these dismal statistics, a better understanding of the biology of liver metastasis, particularly the early stages that can be targeted for prevention, is essential. Once cancer cells enter the liver, several different scenarios may occur. The cancer cells may be immediately destroyed by local defence mechanisms, they may enter a state of dormancy as solitary cells and never produce a metastasis, initiate a short-lived process of proliferation that is aborted before a metastasis is established or actively proliferate to form macrometastases. The chapters in Part I of this book provide insight into the cellular/molecular mechanisms that determine which of these scenarios prevails. Written by experts researchers in the filed of metastasis, these chapters provide state-of-the art reviews on the cellular and molecular processes that impact the early stages of the metastatic process. The unique microenvironment of the liver, its various anatomical, cellular and molecular features and the impact they have on metastasis are highlighted. In addition, the role of inflammation (pre-existing and tumor-induced), host innate and adaptive immune responses, cytokines, chemokines, growth factors and the unique molecular signatures of metastatic tumor cells are reviewed with an underscoring of the translational implications of the current state of knowledge. Against this background, the chapters in Part II of the book provide critical reviews on major aspects of the clinical management of hepatic metastases. These include imaging strategies, surgical and chemotherapeutic treatment approaches and the use of targeted biological therapeutics such as anti-angiogenic drugs as treatment modalities. By combining information on biological and clinical aspects of liver metastasis, this volume will serve as an excellent resource for scientists, clinicians, clinician/ scientists and trainees in the domains of oncology, surgical oncology, hepatobiliary physiology and radiology.

Author: Mauro Monteiro Correia
Publisher: Springer Nature
ISBN: 3030254860
Category : Medical
Languages : en
Pages : 597

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Book Description
Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.