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Lung Health and the Exposome

Lung Health and the Exposome PDF Author: Sumita B. Khatri
Publisher: Springer Nature
ISBN: 3030901858
Category : Medical
Languages : en
Pages : 210

Book Description
This book is ideal for the practicing clinician looking to better understand how our environment impacts the lung. A compilation of reviews explores how clinicians can be aware and better determine environmental effects on lung health, and provides guidelines for medical providers to diagnose, counsel and mitigate risk. Various lung diseases are affected by the external environment. Asthma is common, however other airways diseases, such as interstitial lung disease, malignancies, and even adverse effects from reactions treatments for other medical conditions can affect the health of the lungs. While there are books and chapters written on occupational lung disease and environmental causes of asthma, the intent of this body of work is to address the exposome and the effects on a broader group of lung disease. In addition to information on traditional exposure sources, such as air pollution and occupational exposures, this resource explores newer areas of interest, including lung disease from recreational inhalants and the role of climate change on lung health. Written by expert respiratory specialists, the articles cover a wide range of topics, including: How air pollution effects airways disease, including asthma, COPD, and cystic fibrosis Risk factors and effects of indoor mold exposure Both medical and non-medical exposures that increase the risk of or cause interstitial lung disease (ILD) also known as diffuse parenchymal lung disease (DPLD) Acute and chronic lung disease associated with recreational inhalants The epidemiologic and molecular mechanisms of air pollution effects on pulmonary hypertension Climate change and weather-related lung health issues Areas in this field that need further evaluation

Lung Health and the Exposome

Lung Health and the Exposome PDF Author: Sumita B. Khatri
Publisher: Springer Nature
ISBN: 3030901858
Category : Medical
Languages : en
Pages : 210

Book Description
This book is ideal for the practicing clinician looking to better understand how our environment impacts the lung. A compilation of reviews explores how clinicians can be aware and better determine environmental effects on lung health, and provides guidelines for medical providers to diagnose, counsel and mitigate risk. Various lung diseases are affected by the external environment. Asthma is common, however other airways diseases, such as interstitial lung disease, malignancies, and even adverse effects from reactions treatments for other medical conditions can affect the health of the lungs. While there are books and chapters written on occupational lung disease and environmental causes of asthma, the intent of this body of work is to address the exposome and the effects on a broader group of lung disease. In addition to information on traditional exposure sources, such as air pollution and occupational exposures, this resource explores newer areas of interest, including lung disease from recreational inhalants and the role of climate change on lung health. Written by expert respiratory specialists, the articles cover a wide range of topics, including: How air pollution effects airways disease, including asthma, COPD, and cystic fibrosis Risk factors and effects of indoor mold exposure Both medical and non-medical exposures that increase the risk of or cause interstitial lung disease (ILD) also known as diffuse parenchymal lung disease (DPLD) Acute and chronic lung disease associated with recreational inhalants The epidemiologic and molecular mechanisms of air pollution effects on pulmonary hypertension Climate change and weather-related lung health issues Areas in this field that need further evaluation

The Exposome

The Exposome PDF Author: Gary W. Miller
Publisher: Elsevier
ISBN: 0124172180
Category : Science
Languages : en
Pages : 118

Book Description
The Exposome: A Primer is the first book dedicated to exposomics, detailing the purpose and scope of this emerging field of study, its practical applications and how it complements a broad range of disciplines. Genetic causes account for up to a third of all complex diseases. (As genomic approaches improve, this is likely to rise.) Environmental factors also influence human disease but, unlike with genetics, there is no standard or systematic way to measure the influence of environmental exposures. The exposome is an emerging concept that hopes to address this, measuring the effects of life-long environmental exposures on health and how these exposures can influence disease. This systematic introduction considers topics of managing and integrating exposome data (including maps, models, computation, and systems biology), "-omics"-based technologies, and more. Both students and scientists in disciplines including toxicology, environmental health, epidemiology, and public health will benefit from this rigorous yet readable overview.

Breathing Lessons: A Doctor's Guide to Lung Health

Breathing Lessons: A Doctor's Guide to Lung Health PDF Author: MeiLan K. Han
Publisher: W. W. Norton & Company
ISBN: 0393866637
Category : Health & Fitness
Languages : en
Pages : 192

Book Description
An authoritative, accessible guide to how our lungs work and how to protect them. Every day, our lungs circulate 11,000 liters of air, provide us with life-sustaining oxygen, and allow us to speak, sing, and smell. It’s no secret that our lungs are one of our most vital organs, and yet most of us pay them little attention. The COVID-19 pandemic, however, has reminded us of the importance of our lungs, and sparked interest in their function and the risks they face. In Breathing Lessons, leading pulmonologist and national spokesperson for the American Lung Association Dr. MeiLan K. Han takes readers on a fascinating tour of this neglected yet crucial organ. Han explains the wonder of breathing and reveals how the lungs serve as the body’s first line of defense. She provides a timely overview of the latest scientific thinking about the leading respiratory risks—including indoor and outdoor pollution, smoking and vaping, wildfire smoke, and viruses like SARS-CoV-2—and offers practical advice on how to protect the lungs at each stage of our lives, beginning in the womb. She outlines the major categories of chronic lung disease and demystifies the process lung doctors go through in making a diagnosis and recommending treatments. With authority as both practitioner and medical researcher, Han argues powerfully for social policies that make preserving lung health a national priority. Breathing Lessons is a rallying cry for lung health and an urgent call to start giving our lungs the attention they deserve.

A Clinical Guide to Occupational and Environmental Lung Diseases

A Clinical Guide to Occupational and Environmental Lung Diseases PDF Author: Yuh-Chin T. Huang
Publisher: Springer Science & Business Media
ISBN: 1627031499
Category : Medical
Languages : en
Pages : 330

Book Description
A Clinical Guide to Occupational and Environmental Lung Diseases delivers a concise compendium to the diagnosis and management of occupational and environmental lung diseases, incorporating evidence-based guidelines where available. Each chapter provides an updated review and a practical approach to different occupational and environmental lung diseases. With rapidly changing technology, new conditions and exposures will undoubtedly emerge. Clinicians need to remain vigilant about assessing the potential link between lung diseases and environmental exposures, and this book provides a practical guide to recognize, diagnose, and prevent occupational and environmental lung diseases. Written for practicing clinicians including internists, pulmonologists, and primary care providers, as well as industrial hygienists and environmental regulators, A Clinical Guide to Occupational and Environmental Lung Diseases is a timely and important new volume and an invaluable contribution to the literature.

WHO global air quality guidelines

WHO global air quality guidelines PDF Author: Weltgesundheitsorganisation
Publisher: World Health Organization
ISBN: 9240034226
Category : Nature
Languages : en
Pages : 300

Book Description
The main objective of these updated global guidelines is to offer health-based air quality guideline levels, expressed as long-term or short-term concentrations for six key air pollutants: PM2.5, PM10, ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide. In addition, the guidelines provide interim targets to guide reduction efforts of these pollutants, as well as good practice statements for the management of certain types of PM (i.e., black carbon/elemental carbon, ultrafine particles, particles originating from sand and duststorms). These guidelines are not legally binding standards; however, they provide WHO Member States with an evidence-informed tool, which they can use to inform legislation and policy. Ultimately, the goal of these guidelines is to help reduce levels of air pollutants in order to decrease the enormous health burden resulting from the exposure to air pollution worldwide.

Preventing Disease Through Healthy Environments

Preventing Disease Through Healthy Environments PDF Author: Annette Prüss-Üstün
Publisher: World Health Organization
ISBN: 9241565195
Category : Medical
Languages : en
Pages : 173

Book Description
"The main message emerging from this new comprehensive global assessment is that premature death and disease can be prevented through healthier environments--and to a significant degree. Analysing the latest data on the environment-disease nexus and the devastating impact of environmental hazards and risks on global health, backed up by expert opinion, this report covers more than 130 diseases and injuries. The analysis shows that 23% of global deaths (and 26% of deaths among children under five) are due to modifiable environmental factors--and therefore can be prevented. Stroke, ischaemic heart disease, diarrhoea and cancers head the list. People in low-income countries bear the greatest disease burden, with the exception of noncommunicable diseases. The report's unequivocal evidence should add impetus to coordinating global efforts to promote healthy environments--often through well-established, cost-effective interventions. This analysis will inform those who want to better understand the transformational spirit of the Sustainable Development Goals agreed by Heads of State in September 2015. The results of the analysis underscore the pressing importance of stronger intersectoral action to create healthier environments that will contribute to sustainably improving the lives of millions around the world."--Page 4 of cover.

Exhaled Biomarkers

Exhaled Biomarkers PDF Author: I. Horvath
Publisher: European Respiratory Society
ISBN: 1849840059
Category : Medical
Languages : en
Pages : 261

Book Description
Exhaled air contains numerous substances, often in extremely low concentrations. The development of sensitive detection techniques has made it possible to examine the composition of exhaled air in relation to a variety of airway diseases and other disorders. In this book, an overview of current cutting-edge breath analysis techniques and their clinical applications is provided for the clinician. The various contributions give a fascinating perspective of a future where new, highly sensitive methodologies will enable clinicians to diagnose and monitor a wide variety of diseases merely by taking.

Implementing Precision Medicine in Best Practices of Chronic Airway Diseases

Implementing Precision Medicine in Best Practices of Chronic Airway Diseases PDF Author: Ioana Agache
Publisher: Academic Press
ISBN: 0128134720
Category : Medical
Languages : en
Pages : 236

Book Description
Implementing Precision Medicine in Best Practices of Chronic Airway Diseases provides a comprehensive overview of the application of precision medicine in airway diseases with a goal of promoting optimal control of disease, higher patient satisfaction and disease prevention. As medical research continues to fund this area, the book highlights the need for implementation of the principles of precision medicine into the bedside management of chronic airway diseases. It is clear that chronic airway diseases are heterogeneous and that a personalized approach is warranted whereby treatment is tailored to the level of the individual patient.Written for basic researchers, medical doctors and other healthcare practitioners this book provides guidance on the implementation of the principles of precision medicine into further research and daily clinical practice. - Bridges the gap between precision medicine research and the implementation of the principles into daily clinical practice - Includes contributions from key opinion leaders in the field of airway disease giving a worldwide perspective - Discusses precision medicine in terms of personalized and stratified medicine, biomarkers, prediction of success, participation of the patient and prevention of disease

The Lung Microbiome

The Lung Microbiome PDF Author: Michael J. Cox
Publisher: European Respiratory Society
ISBN: 1849841020
Category : Medical
Languages : en
Pages : 261

Book Description
Studying the lung microbiome requires a specialist approach to sampling, laboratory techniques and statistical analysis. This Monograph introduces the techniques used and discusses how respiratory sampling, 16S rRNA gene sequencing, metagenomics and the application of ecological theory can be used to examine the respiratory microbiome. It examines the different components of the respiratory microbiome: viruses and fungi in addition to the more frequently studied bacteria. It also considers a range of contexts from the paediatric microbiome and how this develops to disease of all ages including asthma and chronic obstructive pulmonary disease, chronic suppurative lung diseases, interstitial lung diseases, acquired pneumonias, transplantation, cancer and HIV, and the interaction of the respiratory microbiome and the environment.

The Exposome

The Exposome PDF Author: Gary W. Miller
Publisher: Academic Press
ISBN: 0128140798
Category : Science
Languages : en
Pages : 298

Book Description
The Exposome: A New Paradigm for the Environment and Health, Second Edition, is a thoroughly expanded and updated edition of The Exposome: A Primer, the first book dedicated to the topic. This new release outlines the purpose and scope of this emerging field of study, its practical applications, and how it complements a broad range of disciplines. The book contains sections on -omics-based technologies, newer detection methods, managing and integrating exposome data (including maps, models, computation and systems biology), and more. Both students and scientists in toxicology, environmental health, epidemiology and public health will benefit from this rigorous, yet readable, overview. This updated edition includes a more in-depth examination of the exposome, including full references, further reading and thought questions. Addresses an emerging field that connects with other exciting disciplines Written by a single author who is a leader in the field Includes new content that widely expands on the first edition