Life - The Epic Story of Our Mitochondria

Life - The Epic Story of Our Mitochondria PDF Author: Lee Know ND
Publisher: FriesenPress
ISBN: 1460251814
Category : Health & Fitness
Languages : en
Pages : 266

Book Description
"Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion-mitochondria and bioenergetics. This legendary saga began over two billion years ago, when one bacterium entered another without being digested, ultimately creating the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that are responsible for this life-giving energy. Yet, current research has also revealed a dark side; many seemingly unconnected degenerative diseases have their roots in dysfunctional mitochondria. Modern research, however, has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. By reading this book, you are about to dive into this epic story, and learn how to add years to your life, and life to your years."--Back cover.

Mitochondria and the Future of Medicine

Mitochondria and the Future of Medicine PDF Author: Lee Know
Publisher: Chelsea Green Publishing
ISBN: 1603587675
Category : Health & Fitness
Languages : en
Pages : 274

Book Description
With information for patients and practitioners on optimizing mitochondrial function for greater health and longevity Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion: mitochondria and bioenergetics. In Mitochondria and the Future of Medicine, Naturopathic Doctor Lee Know tells the epic story of mitochondria, the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that have been responsible for this life-giving energy. By understanding how our mitochondria work, in fact, it is possible to add years to our lives, and life to our years. Current research, however, has revealed a dark side: many seemingly disconnected degenerative diseases have tangled roots in dysfunctional mitochondria. However, modern research has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. Lee Know offers cutting-edge information on supplementation and lifestyle changes for mitochondrial optimization, such as CoQ10, D-Ribose, cannabinoids, and ketogenic dietary therapy, and how to implement their use successfully. Mitochondria and the Future of Medicine is an invaluable resource for practitioners interested in mitochondrial medicine and the true roots of chronic illness and disease, as well as anyone interested in optimizing their health.

Power, Sex, Suicide

Power, Sex, Suicide PDF Author: Nick Lane
Publisher: OUP Oxford
ISBN: 0191622591
Category : Science
Languages : en
Pages : 553

Book Description
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. 'An extraordinary account of groundbreaking modern science... The book abounds with interesting and important ideas.' Mark Ridley, Department of Zoology, University of Oxford

Oxygen

Oxygen PDF Author: Nick Lane
Publisher: Oxford University Press, USA
ISBN: 0198607830
Category : Health & Fitness
Languages : en
Pages : 385

Book Description
Oxygen offers fresh perspectives on our own lives and deaths, explaining modern killer diseases, why we age, and what we can do about it. Advancing revelatory new ideas, following chains of evidence, the book ranges through many disciplines, from environmental sciences to molecular medicine. Damage to DNA caused by oxidative stress appears to explain aging and many of its diseases, hence the popularity in alternative health circles of antioxidants. But antioxidants alone fail to prevent aging. Lane suggests two different avenues of study: modulation of the immune system, which generates free radicals as part of its defense against infectious diseases; and ways of improving the health of our cellular mitochondria, on which many age-related ailments seem to depend. Provocative and complexly argued. Copyright ©Kirkus Reviews, used with permission.

The Vital Question

The Vital Question PDF Author: Nick Lane
Publisher:
ISBN: 9781781250372
Category : Cells
Languages : en
Pages : 0

Book Description
A game-changing book on the origins of life, called the most important scientific discovery 'since the Copernican revolution' in The Observer.

Life Ascending

Life Ascending PDF Author: Nick Lane
Publisher: Profile Books
ISBN: 1847652220
Category : Science
Languages : en
Pages : 353

Book Description
Winner of the 2010 Royal Society Prize for science books Powerful new research methods are providing fresh and vivid insights into the makeup of life. Comparing gene sequences, examining the atomic structure of proteins and looking into the geochemistry of rocks have all helped to explain creation and evolution in more detail than ever before. Nick Lane uses the full extent of this new knowledge to describe the ten greatest inventions of life, based on their historical impact, role in living organisms today and relevance to current controversies. DNA, sex, sight and consciousnesses are just four examples. Lane also explains how these findings have come about, and the extent to which they can be relied upon. The result is a gripping and lucid account of the ingenuity of nature, and a book which is essential reading for anyone who has ever questioned the science behind the glories of everyday life.

One Plus One Equals One

One Plus One Equals One PDF Author: John Archibald
Publisher: OUP Oxford
ISBN: 0191636274
Category : Science
Languages : en
Pages : 220

Book Description
We are in the midst of a revolution. It is a scientific revolution built upon the tools of molecular biology, with which we probe and prod the living world in ways unimaginable a few decades ago. Need to track a bacterium at the root of a hospital outbreak? No problem: the offending germ's complete genetic profile can be obtained in 24 hours. We insert human DNA into E. coli bacteria to produce our insulin. It is natural to look at biotechnology in the 21st century with a mix of wonder and fear. But biotechnology is not as 'unnatural' as one might think. All living organisms use the same molecular processes to replicate their genetic material and the same basic code to 'read' their genes. The similarities can be seen in their DNA. Here, John Archibald shows how evolution has been 'plugging-and-playing' with the subcellular components of life from the very beginning and continues to do so today. For evidence, we need look no further than the inner workings of our own cells. Molecular biology has allowed us to gaze back more than three billion years, revealing the microbial mergers and acquisitions that underpin the development of complex life. One Plus One Equals One tells the story of how we have come to this realization and its implications.

A Life Decoded

A Life Decoded PDF Author: J. Craig Venter
Publisher: Penguin
ISBN: 1101202564
Category : Biography & Autobiography
Languages : en
Pages : 400

Book Description
The triumphant memoir of the man behind one of the greatest feats in scientific history Of all the scientific achievements of the past century, perhaps none can match the deciphering of the human genetic code, both for its technical brilliance and for its implications for our future. In A Life Decoded, J. Craig Venter traces his rise from an uninspired student to one of the most fascinating and controversial figures in science today. Here, Venter relates the unparalleled drama of the quest to decode the human genome?a goal he predicted he could achieve years earlier and more cheaply than the government-sponsored Human Genome Project, and one that he fulfilled in 2001. A thrilling story of detection, A Life Decoded is also a revealing, and often troubling, look at how science is practiced today.

Evolution

Evolution PDF Author: Carl Zimmer
Publisher: Harper Collins
ISBN: 0062038230
Category : Science
Languages : en
Pages : 530

Book Description
“This brilliant book is a virtual Voyage of the Beagle! Carl Zimmer shows, with the benefit of a hundred and fifty years of hindsight, how right Darwin was.” —Steve Jones, author of Darwin’s Ghost Darwin’s The Origin of Species was breathtaking—beautifully written, staunchly defended, defiantly radical. Yet it emerged long before modern genetics, molecular biology, and contemporary findings in paleontology. In this remarkable book, a rich and up-to-date view of evolution is presented that explores the far-reaching implications of Darwin’s theory. At a time when controversies surrounding creationism and education are bursting into public consciousness, this book’s emphasis on the power, significance, and relevance of evolution will make it a catalyst for public debate. Evolution marks a turning point in the 150-year debate and will be an indispensable asset to any serious reader with an interest in the life sciences, a passion for truth in education, or a concern for the future of the planet. “The evolution of life over four billion years is a grand narrative, full of plots, intrigues, surprises and deaths. Carl Zimmer tells the tale with zest and style.” —Matt Ridley, New York Times–bestselling author “Proceeding from the flurry of preparations for Darwin’s famous voyage, Carl Zimmer leads us off on a journey of our own, tracking the development—and the implications—of one of the most powerful ideas in the biological sciences.” —Scientific American “Science writer Zimmer does a superb job of providing a sweeping overview of most of the topics critical to understanding evolution, presenting his material from both a historical and a topical perspective.” —Publishers Weekly “Popular science that will truly be popular.” —Booklist

Origin Story

Origin Story PDF Author: David Christian
Publisher: Little, Brown Spark
ISBN: 0316392022
Category : History
Languages : en
Pages : 304

Book Description
This New York Times bestseller "elegantly weaves evidence and insights . . . into a single, accessible historical narrative" (Bill Gates) and presents a captivating history of the universe -- from the Big Bang to dinosaurs to mass globalization and beyond. Most historians study the smallest slivers of time, emphasizing specific dates, individuals, and documents. But what would it look like to study the whole of history, from the big bang through the present day -- and even into the remote future? How would looking at the full span of time change the way we perceive the universe, the earth, and our very existence? These were the questions David Christian set out to answer when he created the field of "Big History," the most exciting new approach to understanding where we have been, where we are, and where we are going. In Origin Story, Christian takes readers on a wild ride through the entire 13.8 billion years we've come to know as "history." By focusing on defining events (thresholds), major trends, and profound questions about our origins, Christian exposes the hidden threads that tie everything together -- from the creation of the planet to the advent of agriculture, nuclear war, and beyond. With stunning insights into the origin of the universe, the beginning of life, the emergence of humans, and what the future might bring, Origin Story boldly reframes our place in the cosmos.