Author: H. M. PinedoPublisher:
ISBN:
Category : Medical
Languages : en
Pages : 140
Book Description
Leucovorin Modulation of Fluoropyrimidines
Author: H. M. PinedoPublisher:
ISBN:
Category : Medical
Languages : en
Pages : 140
Book Description
The Expanding Role of Folates and Fluoropyrimidines in Cancer Chemotherapy
Author: Y. RustumPublisher: Springer Science & Business Media
ISBN: 1468456075
Category : Medical
Languages : en
Pages : 328
Book Description
Fluoropyrimidines in Cancer Therapy
Author: Youcef M. RustumPublisher: Springer Science & Business Media
ISBN: 1592593372
Category : Medical
Languages : en
Pages : 331
Book Description
Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents.
Biochemical and Pharmacological Determinants of Modulation of Fluoropyrimidine Actions by Leucovorin
Author: Zheng-Gang ZhangBiochemical Modulation of 5-fluorouracil by Uridine and Leucovorin
Author: Giovanni Codacci-PisanelliPublisher:
ISBN:
Category :
Languages : en
Pages : 127
Book Description
Novel Approaches to Selective Treatments of Human Solid Tumors
Author: Youcef M. RustumPublisher: Springer Science & Business Media
ISBN: 1461524881
Category : Medical
Languages : en
Pages : 306
Book Description
Holland-Frei Cancer Medicine
Author: Robert C. Bast, Jr.Publisher: John Wiley & Sons
ISBN: 111900084X
Category : Medical
Languages : en
Pages : 2004
Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Combination Cancer Therapy
Author: Gary K. SchwartzPublisher: Springer Science & Business Media
ISBN: 1592598641
Category : Medical
Languages : en
Pages : 289
Book Description
Expert physician-scientists and clinicians review those combinations of novel target agents classic chemotherapies that hold the most promise for the future of medical oncology, and detail their optimal sequence, pharmacokinetic interactions, and interaction with downstream cellular signals. The combinations run the gamut of targeted therapies against cell surface receptors (EGF-R and HER2), the cell cycle (the CDKs), signal transduction events (PKC and NF-kB), apoptosis (bcl-2), as well as focused therapies in ovarian cancer, hematologic diseases, and breast cancer. The authors emphasize novel translational approaches that are rapidly moving from the laboratory bench top to the patient's bedside for the future treatments in cancer therapy.
Journal of the National Cancer Institute
Author: Rectal Cancer Treatment
Author: M.W. BüchlerPublisher: Springer Science & Business Media
ISBN: 3540274499
Category : Medical
Languages : en
Pages : 284
Book Description
Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.