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Author: Pascal Leclair Publisher: CRC Press ISBN: 1000897575 Category : Science Languages : en Pages : 253
Book Description
Proteins are the workhorses of cells, performing most of the important functions which allow cells to use nutrients and grow, communicate among each other, and importantly, die if aberrant behavior is detected. How were proteins discovered? What is their role in cells? How do dysfunctional proteins give rise to cancers? Landmark Experiments in Protein Science explores the manner in which the inner workings of cells were elucidated, with a special emphasis on the role of proteins. Experiments are discussed in a manner as to understand what questions were being asked that prompted the experiments and what technical challenges were faced in the process; and results are presented and discussed using primary data and graphs. Key Features Describes landmark experiments in cell biology and biochemistry. Discusses the "How" and "Why" of historically important experiments. Includes primary, original data and graphs. Emphasizes biological techniques, that help understand how many of the experiments performed were possible. Documents, chronologically, how each result fed into the next experiments.
Author: Pascal Leclair Publisher: CRC Press ISBN: 1000897575 Category : Science Languages : en Pages : 253
Book Description
Proteins are the workhorses of cells, performing most of the important functions which allow cells to use nutrients and grow, communicate among each other, and importantly, die if aberrant behavior is detected. How were proteins discovered? What is their role in cells? How do dysfunctional proteins give rise to cancers? Landmark Experiments in Protein Science explores the manner in which the inner workings of cells were elucidated, with a special emphasis on the role of proteins. Experiments are discussed in a manner as to understand what questions were being asked that prompted the experiments and what technical challenges were faced in the process; and results are presented and discussed using primary data and graphs. Key Features Describes landmark experiments in cell biology and biochemistry. Discusses the "How" and "Why" of historically important experiments. Includes primary, original data and graphs. Emphasizes biological techniques, that help understand how many of the experiments performed were possible. Documents, chronologically, how each result fed into the next experiments.
Author: Michael Fry Publisher: Academic Press ISBN: 012802108X Category : Science Languages : en Pages : 572
Book Description
Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling
Author: John Horgan Publisher: Basic Books ISBN: 0465050859 Category : Science Languages : en Pages : 368
Book Description
As staff writer for Scientific American, John Horgan has a window on contemporary science unsurpassed in all the world. Who else routinely interviews the likes of Lynn Margulis, Roger Penrose, Francis Crick, Richard Dawkins, Freeman Dyson, Murray Gell-Mann, Stephen Jay Gould, Stephen Hawking, Thomas Kuhn, Chris Langton, Karl Popper, Stephen Weinberg, and E.O. Wilson, with the freedom to probe their innermost thoughts? In The End Of Science, Horgan displays his genius for getting these larger-than-life figures to be simply human, and scientists, he writes, "are rarely so human . . . so at there mercy of their fears and desires, as when they are confronting the limits of knowledge."This is the secret fear that Horgan pursues throughout this remarkable book: Have the big questions all been answered? Has all the knowledge worth pursuing become known? Will there be a final "theory of everything" that signals the end? Is the age of great discoverers behind us? Is science today reduced to mere puzzle solving and adding detains to existing theories? Horgan extracts surprisingly candid answers to there and other delicate questions as he discusses God, Star Trek, superstrings, quarks, plectics, consciousness, Neural Darwinism, Marx's view of progress, Kuhn's view of revolutions, cellular automata, robots, and the Omega Point, with Fred Hoyle, Noam Chomsky, John Wheeler, Clifford Geertz, and dozens of other eminent scholars. The resulting narrative will both infuriate and delight as it mindless Horgan's smart, contrarian argument for "endism" with a witty, thoughtful, even profound overview of the entire scientific enterprise. Scientists have always set themselves apart from other scholars in the belief that they do not construct the truth, they discover it. Their work is not interpretation but simple revelation of what exists in the empirical universe. But science itself keeps imposing limits on its own power. Special relativity prohibits the transmission of matter or information as speeds faster than that of light; quantum mechanics dictates uncertainty; and chaos theory confirms the impossibility of complete prediction. Meanwhile, the very idea of scientific rationality is under fire from Neo-Luddites, animal-rights activists, religious fundamentalists, and New Agers alike. As Horgan makes clear, perhaps the greatest threat to science may come from losing its special place in the hierarchy of disciplines, being reduced to something more akin to literaty criticism as more and more theoreticians engage in the theory twiddling he calls "ironic science." Still, while Horgan offers his critique, grounded in the thinking of the world's leading researchers, he offers homage too. If science is ending, he maintains, it is only because it has done its work so well.
Author: Joseph G. Gall Publisher: CSHL Press ISBN: 9780879696023 Category : Cells Languages : en Pages : 776
Book Description
Annotation Contains 42 seminal papers illustrating advances in cell biology, along with brief commentaries that place the papers in historical and intellectual context. All papers are studies of eukaryotes, and are grouped according to themes of genome organization and replication, transcription, nuclear envelope and nuclear import, mitosis and cell cycle control, cell membrane and extracellular matrix, protein synthesis and membrane traffic, and cytoskeleton. Lacks a subject index. Gall teaches embryology at the Carnegie Institution. McIntosh teaches cell biology at the University of Colorado. Annotation c. Book News, Inc., Portland, OR (booknews.com).
Author: Lauren M. Haggerty Publisher: Nova Biomedical Books ISBN: 9781612096568 Category : Proteins Languages : en Pages : 0
Book Description
To understand the functions of proteins at a molecular level, it is often necessary to determine their three-dimensional structure. A protein may undergo reversible structural changes in performing its biological function. This book presents current research in the study of protein structure. Topics discussed include enzyme immobilisation; structural characteristics of fibrous and globular proteins; mathematical modelling of helical protein structures; three approaches for classifying protein tertiary structures and spectral and fluorescence analysis of protein structure.
Author: Anton Torres Publisher: ISBN: 9781639873876 Category : Languages : en Pages : 0
Book Description
Large biomolecules which comprise one or more long chains of amino acid residues are known as proteins. The sequence of amino acids in a protein is governed by the gene sequence. The sequence is encoded in the genetic code which enumerates 20 standard amino acids. Polypeptides are linear chains of amino acid residues. Every protein comprises at least one long polypeptide. Peptide bonds are responsible for bonding individual amino acid residues together. Protein science is the branch of science which deals with the function, structure and biochemical significance of proteins. It also attempts to develop an understanding about the role of proteins in molecular and cell biology, evolution and genetics. Proteins are responsible for performing a wide variety of functions which encompasses response to stimulus, DNA replication, and transportation of molecules. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in the field of protein science. The various sub-fields of protein science along with technological progress that have future implications are glanced at herein. This book will help the readers in keeping pace with the rapid changes in this field.
Author: Michel Morange Publisher: Harvard University Press ISBN: 0674281365 Category : Science Languages : en Pages : 529
Book Description
In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.
Author: Pascal Leclair
Author: Pascal Leclair
Author: Michael Fry
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Author: John E. Coligan
Author: John Horgan
Author: Joseph G. Gall
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Author: Lauren M. Haggerty
Author: Anton Torres
Author: Michel Morange