Knowledge Discovery in Life Science Literature PDF Download

Author: Christopher J. O. Baker
Publisher: Springer Science & Business Media
ISBN: 0387484388
Category : Science
Languages : en
Pages : 449

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Book Description
This book introduces advanced semantic web technologies, illustrating their utility and highlighting their implementation in biological, medical, and clinical scenarios. It covers topics ranging from database, ontology, and visualization to semantic web services and workflows. The volume also details the factors impacting on the establishment of the semantic web in life science and the legal challenges that will impact on its proliferation.

Author: Eric G. Bremer
Publisher: Springer Science & Business Media
ISBN: 3540328092
Category : Computers
Languages : en
Pages : 159

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Book Description
This book constitutes the refereed proceedings of the International Workshop on Knowledge Discovery in Life Science Literature, KDLL 2006, held in conjunction with the 10th Pacific-Asia Conference on Knowledge Discovery and Data Mining (PAKDD 2006). The 12 revised full papers presented together with two invited talks were carefully reviewed and selected for inclusion in the book. The papers cover all topics of knowledge discovery in life science data.

Author: Mourad Elloumi
Publisher: John Wiley & Sons
ISBN: 1118617118
Category : Computers
Languages : en
Pages : 1192

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Book Description
The first comprehensive overview of preprocessing, mining,and postprocessing of biological data Molecular biology is undergoing exponential growth in both thevolume and complexity of biological data—and knowledgediscovery offers the capacity to automate complex search and dataanalysis tasks. This book presents a vast overview of the mostrecent developments on techniques and approaches in the field ofbiological knowledge discovery and data mining (KDD)—providingin-depth fundamental and technical field information on the mostimportant topics encountered. Written by top experts, Biological Knowledge DiscoveryHandbook: Preprocessing, Mining, and Postprocessing of BiologicalData covers the three main phases of knowledge discovery (datapreprocessing, data processing—also known as datamining—and data postprocessing) and analyzes both verificationsystems and discovery systems. BIOLOGICAL DATA PREPROCESSING Part A: Biological Data Management Part B: Biological Data Modeling Part C: Biological Feature Extraction Part D Biological Feature Selection BIOLOGICAL DATA MINING Part E: Regression Analysis of Biological Data Part F Biological Data Clustering Part G: Biological Data Classification Part H: Association Rules Learning from Biological Data Part I: Text Mining and Application to Biological Data Part J: High-Performance Computing for Biological DataMining Combining sound theory with practical applications in molecularbiology, Biological Knowledge Discovery Handbook is idealfor courses in bioinformatics and biological KDD as well as forpractitioners and professional researchers in computer science,life science, and mathematics.

Author: Xiaoling Shu
Publisher: University of California Press
ISBN: 0520339991
Category : Social Science
Languages : en
Pages : 263

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Book Description
Knowledge Discovery in the Social Sciences helps readers find valid, meaningful, and useful information. It is written for researchers and data analysts as well as students who have no prior experience in statistics or computer science. Suitable for a variety of classes—including upper-division courses for undergraduates, introductory courses for graduate students, and courses in data management and advanced statistical methods—the book guides readers in the application of data mining techniques and illustrates the significance of newly discovered knowledge. Readers will learn to: • appreciate the role of data mining in scientific research • develop an understanding of fundamental concepts of data mining and knowledge discovery • use software to carry out data mining tasks • select and assess appropriate models to ensure findings are valid and meaningful • develop basic skills in data preparation, data mining, model selection, and validation • apply concepts with end-of-chapter exercises and review summaries

Author: Petr Skoda
Publisher: Elsevier
ISBN: 0128191554
Category : Computers
Languages : en
Pages : 474

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Book Description
Knowledge Discovery in Big Data from Astronomy and Earth Observation: Astrogeoinformatics bridges the gap between astronomy and geoscience in the context of applications, techniques and key principles of big data. Machine learning and parallel computing are increasingly becoming cross-disciplinary as the phenomena of Big Data is becoming common place. This book provides insight into the common workflows and data science tools used for big data in astronomy and geoscience. After establishing similarity in data gathering, pre-processing and handling, the data science aspects are illustrated in the context of both fields. Software, hardware and algorithms of big data are addressed. Finally, the book offers insight into the emerging science which combines data and expertise from both fields in studying the effect of cosmos on the earth and its inhabitants. - Addresses both astronomy and geosciences in parallel, from a big data perspective - Includes introductory information, key principles, applications and the latest techniques - Well-supported by computing and information science-oriented chapters to introduce the necessary knowledge in these fields

Author: Andreas Holzinger
Publisher: Springer
ISBN: 3662439689
Category : Computers
Languages : en
Pages : 373

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Book Description
One of the grand challenges in our digital world are the large, complex and often weakly structured data sets, and massive amounts of unstructured information. This “big data” challenge is most evident in biomedical informatics: the trend towards precision medicine has resulted in an explosion in the amount of generated biomedical data sets. Despite the fact that human experts are very good at pattern recognition in dimensions of = 3; most of the data is high-dimensional, which makes manual analysis often impossible and neither the medical doctor nor the biomedical researcher can memorize all these facts. A synergistic combination of methodologies and approaches of two fields offer ideal conditions towards unraveling these problems: Human–Computer Interaction (HCI) and Knowledge Discovery/Data Mining (KDD), with the goal of supporting human capabilities with machine learning./ppThis state-of-the-art survey is an output of the HCI-KDD expert network and features 19 carefully selected and reviewed papers related to seven hot and promising research areas: Area 1: Data Integration, Data Pre-processing and Data Mapping; Area 2: Data Mining Algorithms; Area 3: Graph-based Data Mining; Area 4: Entropy-Based Data Mining; Area 5: Topological Data Mining; Area 6 Data Visualization and Area 7: Privacy, Data Protection, Safety and Security.

Author: Peter Bruza
Publisher: Springer Science & Business Media
ISBN: 3540686908
Category : Computers
Languages : en
Pages : 200

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Book Description
This is the first coherent book on literature-based discovery (LBD). LBD is an inherently multi-disciplinary enterprise. The aim of this volume is to plant a flag in the ground and inspire new researchers to the LBD challenge.

Author: Xiaohua Hu
Publisher: John Wiley & Sons
ISBN: 9780470124635
Category : Technology & Engineering
Languages : en
Pages : 400

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Book Description
The purpose of this edited book is to bring together the ideas and findings of data mining researchers and bioinformaticians by discussing cutting-edge research topics such as, gene expressions, protein/RNA structure prediction, phylogenetics, sequence and structural motifs, genomics and proteomics, gene findings, drug design, RNAi and microRNA analysis, text mining in bioinformatics, modelling of biochemical pathways, biomedical ontologies, system biology and pathways, and biological database management.

Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309486165
Category : Science
Languages : en
Pages : 257

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Book Description
One of the pathways by which the scientific community confirms the validity of a new scientific discovery is by repeating the research that produced it. When a scientific effort fails to independently confirm the computations or results of a previous study, some fear that it may be a symptom of a lack of rigor in science, while others argue that such an observed inconsistency can be an important precursor to new discovery. Concerns about reproducibility and replicability have been expressed in both scientific and popular media. As these concerns came to light, Congress requested that the National Academies of Sciences, Engineering, and Medicine conduct a study to assess the extent of issues related to reproducibility and replicability and to offer recommendations for improving rigor and transparency in scientific research. Reproducibility and Replicability in Science defines reproducibility and replicability and examines the factors that may lead to non-reproducibility and non-replicability in research. Unlike the typical expectation of reproducibility between two computations, expectations about replicability are more nuanced, and in some cases a lack of replicability can aid the process of scientific discovery. This report provides recommendations to researchers, academic institutions, journals, and funders on steps they can take to improve reproducibility and replicability in science.

Author: Lee Harland
Publisher: Elsevier
ISBN: 1908818247
Category : Computers
Languages : en
Pages : 583

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Book Description
The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems.The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an 'omics' platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. - Discusses a broad range of applications from a variety of sectors - Provides a unique perspective on work normally performed behind closed doors - Highlights the criteria used to compare and assess different approaches to solving problems