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Author: Claudio Ronco Publisher: Karger Medical and Scientific Publishers ISBN: 3805578563 Category : Medical Languages : en Pages : 165
Book Description
Transplantation is today firmly established as the therapy of choice for end-stage organ failure. However, despite recent developments, this therapy is still not without challenges and risks: The necessity to take immunosuppressive drugs for the rest of one's life to prevent allograft rejection trades the morbidity and mortality of organ failure for the risks of infection and cancer as well as for an increased mortality from cardiovascular disease. Thus, there is an urgent need for optimizing the outcome of transplantation by achieving long-term, drug-free graft acceptance with normal organ function.Recently, numerous insights into the dynamic inter-relationship of host immune responses elicited by donor antigen presentation have substantially broadened our understanding of the cascade of events resulting in the acquisition of tolerance. With the pharmacopoeia of the transplant biologist continually expanding, the potential treatment combinations have become baffling and their impact on strategies to induce tolerance even more complex.This book presents novel insights into the pathways of acute rejection and their monitoring through molecular tests, new immunosuppressive agents currently under development as well as the most recent and promising approaches to induce tolerance that have emerged from experimental animal studies.
Author: Claudio Ronco Publisher: Karger Medical and Scientific Publishers ISBN: 3805578563 Category : Medical Languages : en Pages : 165
Book Description
Transplantation is today firmly established as the therapy of choice for end-stage organ failure. However, despite recent developments, this therapy is still not without challenges and risks: The necessity to take immunosuppressive drugs for the rest of one's life to prevent allograft rejection trades the morbidity and mortality of organ failure for the risks of infection and cancer as well as for an increased mortality from cardiovascular disease. Thus, there is an urgent need for optimizing the outcome of transplantation by achieving long-term, drug-free graft acceptance with normal organ function.Recently, numerous insights into the dynamic inter-relationship of host immune responses elicited by donor antigen presentation have substantially broadened our understanding of the cascade of events resulting in the acquisition of tolerance. With the pharmacopoeia of the transplant biologist continually expanding, the potential treatment combinations have become baffling and their impact on strategies to induce tolerance even more complex.This book presents novel insights into the pathways of acute rejection and their monitoring through molecular tests, new immunosuppressive agents currently under development as well as the most recent and promising approaches to induce tolerance that have emerged from experimental animal studies.
Author: James F. Burdick Publisher: ISBN: Category : Medical Languages : en Pages : 808
Book Description
The 26 chapters several new, including one on HIV and several on noninvasive evaluation of the transplant, and the others updated present a broad look at the various forms of kidney rejection, viewing the special problems of infections that occur after transplantation as issues that are integral to
Author: Kenneth Murphy Publisher: Garland Science ISBN: 9780815344575 Category : Medical Languages : en Pages :
Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author: Sandesh Parajuli Publisher: Springer ISBN: 3030001326 Category : Medical Languages : en Pages : 201
Book Description
This concise book provides an overview of the essential aspects of transplant nephrology. Chapters cover patient evaluation, treatment options, complications and post kidney transplant approaches to various common chronic diseases. The importance of proper immunosuppressants adjustment to improve the graft half-life and overall patient quality of life are also highlighted. Up to date and practical, this book gives nephrologists and providers that treat kidney transplant patients a succinct resource on management.
Author: Donald E. Hricik Publisher: Remedica ISBN: 1901346498 Category : Medical Languages : en Pages : 72
Book Description
This publication reviews the immunology of transplant rejection as the basis for modern immunosupression protocols. It also looks at the current criteria for selection of kidney transplant recipients and donors.
Author: Peter Morris Publisher: Elsevier Health Sciences ISBN: 1437710921 Category : Medical Languages : en Pages : 2544
Book Description
Updated to reflect today’s practice guidelines, the new edition of this comprehensive text remains the definitive resource on all aspects of renal transplantation, including immunological, pathological, psychological and ethical considerations. It examines evaluation, management, and procurement of living and deceased donor kidneys, the selection of suitable recipients, interpretation of graft dysfunction, and expected survival based upon a large database of information. There are comprehensive chapters on pediatric renal transplantation and on renal transplantation in the developing world. Extensive tables and figures and comprehensive lists of references with each chapter enhance its value to the transplant team. A multidisciplinary approach from internationally renowned contributors from around the world-many new to this edition-offers practice-applicable guidance for all members of the transplant team, with coverage encompassing applied science, clinical information, and surgical procedures. This 6th edition remains the balanced reference you need to stay apprised of issues important to successful kidney transplantation. Provides a comprehensive description of surgical techniques, immunosuppressive methods, outcomes, risks, and medical considerations related to kidney transplantation, both in adults and children, in one convenient reference. Presents more than 335 superb illustrations-50 in full color-that demonstrate key concepts and nuances of techniques. Features a multidisciplinary approach from contributors from around the world-many new to this edition-offers practice-applicable guidance for all members of the transplant team, with coverage encompassing applied science, clinical information, and surgical procedures. Offers evidence-based decision making advice in renal transplantation-supported by a wealth of data in chapters written by internationally recognized experts-to help you make the most informed clinical decisions. Offers new tables and figures as well as revised and updated chapters that report new data and present current practice guidelines. Features a new chapter on transplantation in the sensitized patient to assist you with transplant cases that present unique challenges. Describes the latest preclinical and clinical immunosuppressive strategies, to help you see the link between clinical issues and the basic sciences. Offers tissue typing methodology updates, equipping you with the newest methods of assessing immune responses to the kidney. Features a new chapter on chronic allograft nephropathy.
Author: Ramadas Pisharody Publisher: Elsevier Health Sciences ISBN: 8131232050 Category : Medical Languages : en Pages : 166
Book Description
The basic functional unit of kidney is the glomerulus. Any renal derangement at that level can lead to a multitude of diseases. The renal as well as glomerular disorders secondary to other causes such as hypertension, diabetes, other vasculites, drugs, malignancies, etc. have been adequately addressed. However, the primary glomerular disorders, due to an ambiguity regarding their genesis, have yet to be explored properly. Though these diseases are clubbed under the common head of "primary", they consist of various distinct subtypes with markedly different mechanisms of pathogenesis, course of the disease, response to treatment and prognoses. This clinical update explores the various types of pimary glomerular diseases with an aim to enhance the reader’s knowledge and aid in timely recognition and precise diagnosis of glomerular diseases to help chart the appropriate treatment of each individual condition. The first chapter elucidates the clinicopathological correlation of primary glomerular diseases to help differentiate them from each other and from other similar differential diagnoses without resorting to renal biopsy in all the cases. The second, third and fourth, chapters explore the various aspects of Proliferative Glomerulonephritis, Idiopathic Nephrotic Syndrome and Heredofamilial Glomerular Diseases. The last chapter summarizes the clinically relevant current perspectives regarding the pathogenesis and treatment modalities of all the primary glomerular diseases. This book will help the readers understand the intricacies of the aspects mentioned above and guide the practitioner to diagnose and manage Primary Glomerular Diseases with special reference to practical experience in India. The authors have put together the most relevant facts about the disease for an easy comprehension and understanding of primary glomerular diseases by practitioners and students across the specialty.
Author: Katherine E. Twombley Publisher: Springer Nature ISBN: 3030747832 Category : Medical Languages : en Pages : 429
Book Description
This book provides a comprehensive overview of the unique challenges inherent in pediatric kidney transplantation. The text reviews the problems faced during each stage of the kidney transplantation process, including the occurrence of infections during the pre-transplant stage, surgical challenges during the actual transplantation, and medication issues during the post-transplant stage. The book also features high-yield case presentations of typical pediatric transplant scenarios, from the pre-transplant management of a child with CAKUT to the evaluation and treatment of antibody mediated rejection in children. Written by experts in the field, Challenges in Pediatric Kidney Transplantation: A Practical Guide is a valuable resource for clinicians, practitioners, and trainees who manage or are interested in this challenging group of patients.
Author: Xin J. Zhou Publisher: Cambridge University Press ISBN: 1316613984 Category : Medical Languages : en Pages : 691
Book Description
An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.
Author: Claudio Ronco
Author: Claudio Ronco
Author: James F. Burdick
Author: Kenneth Murphy
Author: J.-L. Touraine
Author: Sandesh Parajuli
Author: Donald E. Hricik
Author: Peter Morris
Author: Ramadas Pisharody
Author: Katherine E. Twombley
Author: Xin J. Zhou