Molecular Biology of the Cell PDF Download

Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Author: Alpha S. Yap
Publisher: Perspectives Cshl
ISBN: 9781621821519
Category : Cell junctions
Languages : en
Pages : 372

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Book Description
Neighboring cells are linked to each other by multimolecular complexes such as adherens junctions, desmosomes, and gap junctions. These complexes help maintain tissue integrity, act as barriers to permeability, reinforce cell polarity, and allow cells to communicate with each other. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology reviews our understanding of the organization, regulation, and dynamics of cell-cell junctions and the roles they play in morphogenesis, tissue homeostasis, and disease. The contributors examine the assembly and structure of different cell-cell adhesion systems, the plasticity of cell-cell junctions (e.g., during cell migration), and how the junctions act as hubs to sense and transduce various mechanical and chemical signals. The authors also discuss the roles of cell-cell junctions in specific developmental and physiological processes, such as hearing, skeletal myogenesis, and neural circuit assembly, as well as in diseases such as cancer. This volume is therefore an indispensable reference for cell and developmental biologists, as well as anyone interested in understanding the roles of these complexes in human health and disease.

Author: Don Kalb
Publisher: Berghahn Books
ISBN: 9781845450298
Category : History
Languages : en
Pages : 202

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"A book about theory and method in the humanities and social sciences. It reacts to what has become known as the "cultural turn," a shift toward semiotics, discourse, and representations and away from other sorts of determinations that started in the early 1980s and that has dominated social thinking for a long string of years. The book is based in a reconsideration of the meeting of two disciplines that helped to launch the cultural turn: anthropology and history. Specifically, it criticizes the ideas of hermeneutics and "thick description" (Clifford Geertz) that have come to play a key role in the encounter of anthropology and history and then in the cultural turn. It led to the renewed cherishing of what Gupta and Ferguson have called paradigms of "peoples and places," saturated pictures of universes, both small and large, of meaning ina more of less frozen standstill-an intellectual precursor to the cultural xenophobia of our times. Against this, the present book embraces praxis and "critical junctions": the connections in space (in and out of a relations of power and dependency, and what Eric Wolf has called the "interstitial relations" between apparently separate institutional domains. In this way the book adds to the current revival of institutionally based "global ethnography," which studies "up and outward" (the journal of Ethnography is a good example)."--Preface

Author: B.L. Sharma
Publisher: Springer Science & Business Media
ISBN: 146844655X
Category : Science
Languages : en
Pages : 379

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The present-day semiconductor technology would be inconceivable without extensive use of Schottky barrier junctions. In spite of an excellent book by Professor E.H. Rhoderick (1978) dealing with the basic principles of metal semiconductor contacts and a few recent review articles, the need for a monograph on "Metal-Semiconductor Schottky Barrier Junctions and Their Applications" has long been felt by students, researchers, and technologists. It was in this context that the idea of publishing such a monograph by Mr. Ellis H. Rosenberg, Senior Editor, Plenum Publishing Corporation, was considered very timely. Due to the numerous and varied applications of Schottky barrier junctions, the task of bringing it out, however, looked difficult in the beginning. After discussions at various levels, it was deemed appropriate to include only those typical applications which were extremely rich in R&D and still posed many challenges so that it could be brought out in the stipulated time frame. Keeping in view the larger interest, it was also considered necessary to have the different topics of Schottky barrier junctions written by experts.

Author: Norm Konyu
Publisher: Titan Comics
ISBN: 1787738981
Category : Comics & Graphic Novels
Languages : en
Pages : 178

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September 1984 – eleven-year-old Lucas Jones vanishes from the sleepy town of Medford. June 1996 – Lucas finally returns home… and he hasn’t aged a day. Still eleven years old and unable to say where he’s been for the last twelve years, Lucas’ case baffles police and doctors alike. Their only clue is Lucas’ diary – a bizarre fantasy of a town called Kirby Junction where new houses appear out of thin air and people wait for a train that never comes. One psychologist thinks there’s a grain of truth to his tale that just might explain where Lucas has been, and it may be the key to unlocking his terrible dreams…

Author: Marcelino Cereijido
Publisher: CRC Press
ISBN: 1420038532
Category : Medical
Languages : en
Pages : 793

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As the first detailed overview of the subject, Tight Junctions brought together diverse perspectives from leading investigators to provide a multidisciplinary overview of the field. Since its publication in 1992, there has been an explosion of information about tight junctions, particularly in the area of molecular structure, cell and molecular bio

Author: Ekrem Dere
Publisher: Academic Press
ISBN: 012415901X
Category : Medical
Languages : en
Pages : 318

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Book Description
In addition to chemical links across synapses, neurons can also form direct connections via electrical gap junctions. These channels play a key role in brain development and intercellular communication. Dere (pathophysiology of cerebral aging, U. Pierre et Marie Curie, Paris; AP-HP Hôpital Charles Foix, Centre de Recherche et Développement, Ivry-sur-Seine, France) introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction-related diseases due to mutations in connexin genes. International researchers working in this emerging field discuss specific connexin genes and their mechanisms of action and function in the developing neocortx, behavior, and neurological and neuropsychiatric diseases. The text includes color and b&w illustrations including schematic representations and models. Academic Press is an imprint of Elsevier. Annotation ©2013 Book News, Inc., Portland, OR (booknews.com).

Author: Satoshi Kaneko
Publisher: Springer
ISBN: 9811044120
Category : Science
Languages : en
Pages : 92

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This thesis describes improvements to and control of the electrical conductance in single-molecule junctions (SMJs), which have potential applications in molecular electronics, with a focus on the bonding between the metal and molecule. In order to improve the electrical conductance, the π orbital of the molecule is directly bonded to the metal orbital, because anchoring groups, which were typically used in other studies to bind molecule with metal electrodes, became resistive spacers. Using this direct π-binding, the author has successfully demonstrated highly conductive SMJs involving benzene, endohedral metallofullerene Ce@C82, and nitrogen. Subsequently, the author investigated control of the electrical conductance of SMJs using pyrazine. The nitrogen atom in the π-conjugated system of pyrazine was expected to function as an anchoring point, and two bonding states were expected. One originates primarily from the π orbital, while the other originates primarily from an n state of the nitrogen. Measurements of conductance and dI/dV spectra coupled with theoretical calculations revealed that the pyrazine SMJ has bistable conductance states, in which the pyrazine axis is either tilted or parallel with respect to the junction axis. The bistable states were switched by changing the gap size between the metal electrodes using an external force. Notably, it is difficult to change the electrical properties of bulk-state materials using mechanical force. The findings reveal that the electron transport properties of a SMJ can be controlled by designing a proper metal–molecule interface, which has considerable potential for molecular electronics. Moreover, this thesis will serve as a guideline for every step of SMJ research: design, fabrication, evaluation, and control.

Author: Likharev
Publisher: CRC Press
ISBN: 9782881240423
Category : Science
Languages : en
Pages : 640

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"This monograph is intended to give a relatively complete review of Josephson junction dynamics as it stands in the mid-1980's. The main idea of the author is to present the reader with as many useful results as possible by the simplest means, rather than to demonstrate theoretical muscle. This is why almost all the topics requiring elaborate techniques for their analysis are shifted to the ends of the chapters and the most complex chapters, to the end of the book. Topics which are of relatively minor importance for further discussion are mainly presented in the form of 'problems' at the end of the sections." -- from Preface.

Author: Y. Kanno
Publisher: Newnes
ISBN: 0444599525
Category : Science
Languages : en
Pages : 474

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Book Description
Research on intercellular communication through gap junctions has continued to expand, and the meeting on which this book is based brought together many scientists from many different countries and disciplines. In line with the objective of the meeting, this volume focuses on the biological meaning of intercellular communication through gap junctions in various organs. The most recent up-to-date findings have been included in this extensive volume, valuable to all those interested in this rapidly expanding field.