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Author: Hung Y. Fan Publisher: Springer Science & Business Media ISBN: 3642556388 Category : Medical Languages : en Pages : 255
Book Description
Retroviruses have been of great importance to biomedical science for the past half century. Initially, studies on oncogenic animal retroviruses provided important insights into molecular processes in carcinogenesis – most notably the existence and mechanisms of action of oncogenes and proto-oncogenes. Moreover, several human diseases are caused by retroviruses, including AIDS, adult T-cell leukemia and the neurological disease HAM/TSP. The topic of this volume is a relatively unknown animal retrovirus, jaagsiekte sheep retrovirus, the causative agent of transmissible lung cancer in sheep –ovine pulmonary adenocarcinoma. The disease was first documented in South Africa in the 1800s, it has a wide geographical distribution, and it is of economic importance in high endemic regions. However, until very recently the nature of the etiologic agent was unclear, and relatively few laboratories actively studied the disease.
Author: Hung Y. Fan Publisher: Springer Science & Business Media ISBN: 3642556388 Category : Medical Languages : en Pages : 255
Book Description
Retroviruses have been of great importance to biomedical science for the past half century. Initially, studies on oncogenic animal retroviruses provided important insights into molecular processes in carcinogenesis – most notably the existence and mechanisms of action of oncogenes and proto-oncogenes. Moreover, several human diseases are caused by retroviruses, including AIDS, adult T-cell leukemia and the neurological disease HAM/TSP. The topic of this volume is a relatively unknown animal retrovirus, jaagsiekte sheep retrovirus, the causative agent of transmissible lung cancer in sheep –ovine pulmonary adenocarcinoma. The disease was first documented in South Africa in the 1800s, it has a wide geographical distribution, and it is of economic importance in high endemic regions. However, until very recently the nature of the etiologic agent was unclear, and relatively few laboratories actively studied the disease.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309165911 Category : Medical Languages : en Pages : 234
Book Description
In recent years, a number of chronic diseases have been linked, in some cases definitively, to an infectious etiology: peptic ulcer disease with Helicobacter pylori, cervical cancer with several human papillomaviruses, Lyme arthritis and neuroborreliosis with Borrelia burgdorferi, AIDS with the human immunodeficiency virus, liver cancer and cirrhosis with hepatitis B and C viruses, to name a few. The proven and suspected roles of microbes does not stop with physical ailments; infections are increasingly being examined as associated causes of or possible contributors to a variety of serious, chronic neuropsychiatric disorders and to developmental problems, especially in children. The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects, summarizes a two-day workshop held by the Institute of Medicine's Forum on Microbial Threats to address this rapidly evolving field. Participants explored factors driving infectious etiologies of chronic diseases of prominence, identified difficulties in linking infectious agents with chronic outcomes, and discussed broad-based strategies and research programs to advance the field.
Author: Robert Stern Publisher: Academic Press ISBN: 0080921086 Category : Medical Languages : en Pages : 467
Book Description
Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal. The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book will offer a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer. - Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer - Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination - Focuses on understanding the mechanisms that drive tumor cell activation, proliferation, and drug resistance
Author: Stewart Hal Publisher: Elsevier ISBN: 0323147461 Category : Medical Languages : en Pages : 515
Book Description
The Geographical Distribution of Animal Viral Diseases attempts to shed some light on the global distribution of 110 different viral diseases, mainly of livestock and companion animals. The world literature was screened for 110 different viruses, and maps were prepared. These maps delineate the global distribution of pathogenic viruses based on authenticated reports from a variety of reliable sources. Four viruses were categorized as affecting more than one species to a significant degree (astrovirus, rabies, rotaviruses, and Rift Valley fever). The largest number of maps involved viruses that affect humans. Of the 28 viruses a large number were from the California encephalitis group. Ten of the 28 viruses were reported only in the Eastern Hemisphere, 14 only in the Western Hemisphere, and four were worldwide. Birds were the next most frequently affected group with the 15 viruses, followed by pigs with 14 viruses. Overall the vector-borne viruses appear to have much sharper and clear-cut geographical boundaries than the others.
Author: Helmut Popper Publisher: Springer ISBN: 366250491X Category : Medical Languages : en Pages : 708
Book Description
This well-illustrated textbook covers the full range of lung and pleural diseases from the pathologic standpoint. Both diseases of adults and pediatric lung diseases are presented. The book will serve as an excellent guide to the diagnosis of these diseases, but in addition it explains the disease mechanisms and etiology. Genetics and molecular biology are also discussed whenever necessary for a full understanding. The author is an internationally recognized expert who runs courses on lung and pleural pathology attended by participants from all over the world. In compiling this book, he has drawn on more than 30 years’ experience in the field.
Author: David G. Pugh Publisher: Elsevier Health Sciences ISBN: 0323624642 Category : Medical Languages : en Pages : 578
Book Description
**Selected for Doody's Core Titles® 2024 in Veterinary Medicine** Get practical answers from the only guide on the care of sheep, goats, and cervids! Authoritative yet easy to read, Sheep, Goat and Cervid Medicine, 3rd Edition covers all the latest advances in the field, including diseases and medical treatment, surgery, pain management, theriogenology, and nutrition. Clear instructions and hundreds of full-color photographs guide you step by step through common procedures including restraint for examination, administration of drugs, blood collection, and grooming. New to this edition is coverage of deer and elk medicine, reflecting the growing interest in these ruminants. Written by an expert team led by Dr. D.G. Pugh, this comprehensive reference is ideal for veterinarians and also for owners of sheep and goats. - Clear writing style and consistent organization makes the book easy to understand and use, with disease chapters including pathogenesis, clinical signs, diagnosis, treatment, and prevention. - Coverage of both surgery and medicine in each body systems chapter makes it easier to choose between treatment options for specific disorders. - Superbly illustrated surgical procedures clearly demonstrate the steps to follow in performing medical and reproductive surgery. - Diverse, expert contributors include the most experienced authorities, each providing current information on the care of valuable breeding stock as well as pets. - Useful appendixes, now including veterinary feed directives, offer convenient access to information on drugs and drug dosages, fluid therapy, and normal values and conversions. - Consistent, logical format in each body systems chapter makes information easy to find by beginning with physical examination and diagnostic procedures, followed by discussions of common diseases that involve the system. - Comprehensive Feeding and Nutrition chapter covers diet evaluation, method of balancing rations, total parenteral nutrition, and examples of nutritious diets. - Explanation of the differences in normal behavior between sheep and goats shows how they are not the same, and require different methods of treatment. - NEW! Coverage of cervids has been added to chapters throughout the book, reflecting the growing popularity of deer and elk. - NEW! Thorough content updates are made throughout the book and reflect the latest research evidence. - NEW! 170 new clinical photos have been added. - NEW! Anesthesia and Pain Management chapter includes a new section on pain management strategies, reflecting the emphasis on controlling pain in small ruminants. - NEW! Expert Consult website offers an online version of the book, making it easy to search the entire book electronically. - NEW! Two new authors are respected and well-known veterinary medicine experts and educators: Dr. Misty Edmondson and Dr. Thomas Passler.
Author: Robert Klopfleisch Publisher: Springer ISBN: 3319411241 Category : Medical Languages : en Pages : 311
Book Description
This highly readable textbook provides a comprehensive but concise overview of the principles of oncogenesis in veterinary medicine, discussing selected tumors in domestic animals in detail, and addressing cancer diagnostics and therapy. All chapters are illustrated with histological and radiological images to enhance readers’ understanding. Accordingly, the book is a must-have reference guide for all graduate and advanced undergraduate students in Veterinary Medicine with a special interest in oncology.
Author: Moulay Mustapha Ennaji Publisher: Academic Press ISBN: 0128149671 Category : Science Languages : en Pages : 389
Book Description
Emerging and Reemerging Viral Pathogens: Applied Virology Approaches Related to Human, Animal and Environmental Pathogens, Volume Two presents new research information on viruses and their impact on the scientific community. It provides a reference book on certain viruses in humans, animals and vegetal, along with a comprehensive discussion on interspecies interactions. The book then looks at the drug, vaccine and bioinformatical strategies that can be used against these viruses, giving the reader a clear understanding of transmission. The book's end goal is to create awareness that the appearance of newly transmissible pathogens is a global risk that requires shared/adoptable policies for prevention and control. - Covers most emerging viral disease in humans, animals and plants - Provides the most advanced tools and techniques in molecular virology and the modeling of viruses - Creates awareness that the appearance of new transmissible pathogens is a global risk - Highlights the need to adopt shared policies for the prevention and control of infectious diseases
Author: Kari J. Syrjänen Publisher: Springer Science & Business Media ISBN: 3642710972 Category : Medical Languages : en Pages : 527
Book Description
In recent years, papillomaviruses in general and human papillo maviruses in particular have been recognized as possible agents of important diseases, including some forms of human cancer. The purpose of this book is to present a concise panorama of the pre sent status of knowledge of this topic. This knowledge is as impor tant to molecular biologists and virologists as it is to clinicians and pathologists. To bridge the gap among these diverse groups of investigators, we conceived of a book covering a broad spectrum of the basic scientific, clinical, and pathological aspects of diseases associated with papillomaviruses. Although the principal thrust of this book is directed at human papillomaviruses, fundamental knowledge of animal viruses is essential to the current understand ing of the molecular mechanisms of cell transformation. For this reason, a chapter on animal viruses has also been included. Some of the experimental work having to do with the elucidation of transformation and other aspects of interaction between the virus and the cell cannot be based on human papillomaviruses because of a lack of suitable experimental models. Hence, some of the chapters dealing with fundamental aspects of viral molecular biol ogy are based on animal models. We were very fortunate in having persuaded a number of distin guished colleagues to contribute to this work.
Author: Hung Y. Fan
Author: Hung Y. Fan
Author: Institute of Medicine
Author: Robert Stern
Author: Stewart Hal
Author: Alecsandru Ioan Baba
Author: Helmut Popper
Author: David G. Pugh
Author: Robert Klopfleisch
Author: Moulay Mustapha Ennaji
Author: Kari J. Syrjänen