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Author: Ute Linz Publisher: Springer Science & Business Media ISBN: 3642214142 Category : Science Languages : en Pages : 728
Book Description
The book provides a detailed, up-to-date account of the basics, the technology, and the clinical use of ion beams for radiation therapy. Theoretical background, technical components, and patient treatment schemes are delineated by the leading experts that helped to develop this field from a research niche to its current highly sophisticated and powerful clinical treatment level used to the benefit of cancer patients worldwide. Rather than being a side-by-side collection of articles, this book consists of related chapters. It is a common achievement by 76 experts from around the world. Their expertise reflects the diversity of the field with radiation therapy, medical and accelerator physics, radiobiology, computer science, engineering, and health economics. The book addresses a similarly broad audience ranging from professionals that need to know more about this novel treatment modality or consider to enter the field of ion beam therapy as a researcher. However, it is also written for the interested public and for patients who might want to learn about this treatment option.
Author: Ute Linz Publisher: Springer Science & Business Media ISBN: 3642214142 Category : Science Languages : en Pages : 728
Book Description
The book provides a detailed, up-to-date account of the basics, the technology, and the clinical use of ion beams for radiation therapy. Theoretical background, technical components, and patient treatment schemes are delineated by the leading experts that helped to develop this field from a research niche to its current highly sophisticated and powerful clinical treatment level used to the benefit of cancer patients worldwide. Rather than being a side-by-side collection of articles, this book consists of related chapters. It is a common achievement by 76 experts from around the world. Their expertise reflects the diversity of the field with radiation therapy, medical and accelerator physics, radiobiology, computer science, engineering, and health economics. The book addresses a similarly broad audience ranging from professionals that need to know more about this novel treatment modality or consider to enter the field of ion beam therapy as a researcher. However, it is also written for the interested public and for patients who might want to learn about this treatment option.
Author: Hirohiko Tsujii Publisher: Springer Science & Business Media ISBN: 4431544577 Category : Medical Languages : en Pages : 284
Book Description
This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.
Author: C-M Charlie Ma Publisher: CRC Press ISBN: 1439816077 Category : Science Languages : en Pages : 258
Book Description
Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of proton and carbon ion therapy. It presents a thorough introduction for those new to the field while providing a helpful, up-to-date reference for readers already using the therapy in clinical settings.
Author: Marcos d’Ávila Nunes Publisher: Springer ISBN: 3319189832 Category : Science Languages : en Pages : 126
Book Description
This book presents a comparison analysis of two cancer treatment therapies: carbon ion therapy and protontherapy. It is divided in 5 sections. The first ones gives the reader a brief history of Radiotherapy and types of radiation. In the second section, the techniques and equipments, including new ones in development such as Cyclinac , Laser and DWA, are described. The third section describes biophysical (such as stopping power and LET) and biological (such as RBE and OER) properties, the fundamental experiments and clinical area. The fourth section presents models and the fifth section compares both techniques, showing advantages and disadvantages of each, and their similarities.
Author: International Atomic Energy Agency Publisher: ISBN: 9789201078070 Category : Ion bombardment Languages : en Pages : 0
Book Description
This publication covers all the aspects of the relative biological effectiveness (RBE) of ion beams, including laboratory measurements of RBE and the important variables that influence it, dose related quantities and units, and approaches to the clinical use of the concept of RBE based on experimental findings, theoretical models, and previous clinical experience with fast neutrons and ions. This publication is the result of a joint initiative of the IAEA and ICRU (International Commission on Radiation Units and Measurements). It is the only current extensive review of ion beam RBE, and it is expected to be a reference volume for existing and future centres employing ion beams for therapeutic use.
Author: Y. Y. Yonekura Publisher: SAGE Publications Limited ISBN: 9781473918818 Category : Science Languages : en Pages : 116
Book Description
The goal of external beam radiotherapy is to provide precise dose localisation in the treatment volume of the target with minimal damage to the surrounding normal tissues. Ion beams, such as protons and carbon ions, provide excellent dose distributions due primarily to their finite range, allowing a significant reduction of undesired exposure to normal tissues. Careful treatment planning is required for the given type and localisation of the tumour to be treated in order to maximise the treatment efficiency and minimise the dose to the normal tissues. Radiation exposure in the out-of-field volumes arises from secondary neutrons and photons, particle fragments, and photons from activated materials. These unavoidable doses should be considered from the standpoint of radiological protection of the patient. Radiological protection of medical staff at ion beam therapy facilities requires special attention. Appropriate management and control are required for the therapy equipment and also for the air in the treatment room which can be activated by the particle beam and its secondaries. Radiological protection and safety management should always be in conformity with regulatory requirements. The current regulations for occupational exposures in photon radiotherapy are applicable to ion beam radiotherapy with protons or carbon ions. Ion beam radiotherapy requires, however, a more complex treatment system than conventional radiotherapy, and appropriate training of the staff and suitable quality assurance programme are recommended to avoid possible accidental exposure to the patient, to minimise unnecessary doses to normal tissues and to minimise radiation exposure of staff.
Author: Frank Verhaegen Publisher: CRC Press ISBN: 1000455556 Category : Medical Languages : en Pages : 291
Book Description
Targets both students or professionals, both novice and experienced, in medical radiotherapy physics. Combines overviews of development, methods and references to facilitate Monte Carlo studies. Focuses on applications in radiotherapy.
Author: Arabinda Kumar Rath Publisher: Springer ISBN: 8132226224 Category : Medical Languages : en Pages : 194
Book Description
The results of decades of research and development are providing compelling evidence about the efficacy of radiation therapy with proton and carbon ion beams to achieve superior complication free tumor control leading to a world-wide rapid growth in their clinical use. This book contains comprehensive reviews of the state of the art of the technology and physics of heavy charge particle therapy by the experts from the leading cancer centers of world that will be valuable as a practical guide for radiation therapy professionals interested in these modalities.
Author: Ute Linz
Author: Ute Linz
Author: Hirohiko Tsujii
Author: C-M Charlie Ma
Author: SCHULTE
Author: Marcos d’Ávila Nunes
Author: International Atomic Energy Agency
Author: Y. Y. Yonekura
Author: Frank Verhaegen
Author: Thomas Tessonnier
Author: Arabinda Kumar Rath