Investigating the Structure-function Relationship of Cationic Antimicrobial Peptides and Lipopeptides PDF Download

Author: John Tien Jui Cheng
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Author: Mei-Sheung Chan
Publisher:
ISBN: 9781360991344
Category :
Languages : en
Pages :

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Author: Mei-sheung Chan (Ph. D.)
Publisher:
ISBN:
Category : Lactoferrin
Languages : en
Pages : 490

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Author: Katsumi Matsuzaki
Publisher: Springer
ISBN: 9811335885
Category : Medical
Languages : en
Pages : 304

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This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.

Author: G. Jung
Publisher: Springer Science & Business Media
ISBN: 9789072199119
Category : Medical
Languages : en
Pages : 518

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Proceedings of the First International Workshop on Lantibiotics, April 15-18, 1991, Physikzentrum Bad Honnef, F.R.G.

Author: David A. Phoenix
Publisher: John Wiley & Sons
ISBN: 9783527332632
Category : Science
Languages : en
Pages : 0

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Book Description
In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.

Author: W. Chan
Publisher: OUP Oxford
ISBN: 0199637245
Category : Science
Languages : en
Pages : 371

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Since the publication of Atherton and Sheppard's volume, the technique of Fmoc solid-phase peptide synthesis has matured considerably and is now the standard approach for the routine production of peptides. The focus of this new volume is much broader, and covers the essential procedures.

Author: Jianhua Wang
Publisher: Frontiers Media SA
ISBN: 2889760812
Category : Science
Languages : en
Pages : 294

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Author: Angela Jozala
Publisher: BoD – Books on Demand
ISBN: 9535129279
Category : Technology & Engineering
Languages : en
Pages : 314

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Fermentation is a theme widely useful for food, feed and biofuel production. Indeed each of these areas, food industry, animal nutrition and energy production, has considerable presence in the global market. Fermentation process also has relevant applications on medical and pharmaceutical areas, such as antibiotics production. The present book, Fermentation Processes, reflects that wide value of fermentation in related areas. It holds a total of 14 chapters over diverse areas of fermentation research.

Author: Theodor Wieland
Publisher: Springer Science & Business Media
ISBN: 3642758509
Category : Science
Languages : en
Pages : 311

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Book Description
Almost two centuries ago proteins were recognized as the primary materials (proteios = primary) oflife, but the significance and wide role of peptides (from pepsis = digestion) in practically all life pro cesses has only become apparent in the last few decades. Biologi cally active peptides are now being discovered at rapid intervals in the brain and in other organs including the heart, in the skin of amphibians and many other tissues. Peptides and peptide-like compounds are found among toxins and antibiotics. It is unlikely that this process, an almost explosive broadening of the field, will come to a sudden halt. By now it is obvious that Nature has used the combination of a small to moderate number of amino acids to generate a great variety of agonists with specific and often highly sophisticated functions. Thus, peptide chemistry must be regarded as a discipline in its own right, a major branch of biochemistry, fairly separate from the chemistry of proteins. Because of the important role played by synthesis both in the study and in the practical preparation of peptides, their area can be considered as belonging to bio-organic chemistry as well. The already overwhelming and still increasing body of know ledge renders an account of the history of peptide chemistry more and more difficult. It appears therefore timely to look back, to take stock and to recall the important stages in the development of a new discipline.