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Author: Henry C. Tuckwell Publisher: Cambridge University Press ISBN: 9780521352178 Category : Mathematics Languages : en Pages : 292
Book Description
The second part of this two-volume set contains advanced aspects of the quantitative theory of the dynamics of neurons. It begins with an introduction to the effects of reversal potentials on response to synaptic input. It then develops the theory of action potential generation based on the seminal Hodgkin-Huxley equations and gives methods for their solution in the space-clamped and nonspaceclamped cases. The remainder of the book discusses stochastic models of neural activity and ends with a statistical analysis of neuronal data with emphasis on spike trains. The mathematics is more complex in this volume than in the first volume and involves numerical methods of solution of partial differential equations and the statistical analysis of point processes.
Author: Henry C. Tuckwell Publisher: Cambridge University Press ISBN: 9780521352178 Category : Mathematics Languages : en Pages : 292
Book Description
The second part of this two-volume set contains advanced aspects of the quantitative theory of the dynamics of neurons. It begins with an introduction to the effects of reversal potentials on response to synaptic input. It then develops the theory of action potential generation based on the seminal Hodgkin-Huxley equations and gives methods for their solution in the space-clamped and nonspaceclamped cases. The remainder of the book discusses stochastic models of neural activity and ends with a statistical analysis of neuronal data with emphasis on spike trains. The mathematics is more complex in this volume than in the first volume and involves numerical methods of solution of partial differential equations and the statistical analysis of point processes.
Author: Henry C. Tuckwell Publisher: Cambridge University Press ISBN: 9780521022224 Category : Science Languages : en Pages : 304
Book Description
The human brain contains billions of nerve cells whose activity plays a critical role in the way we behave, feel, perceive, and think. This two-volume set explains the basic properties of a neuron--an electrically active nerve cell--and develops mathematical theories for the way neurons respond to the various stimuli they receive. Volume 1 contains descriptions and analyses of the principle mathematical models that have been developed for neurons in the past thirty years. It provides a brief review of the basic neuroanatomical and neurophysiological facts that will form the focus of the mathematical treatment. Tuckwell discusses the mathematical theories, beginning with the theory of membrane potentials. He then goes on to treat the Lapicque model, linear cable theory, and time-dependent solutions of the cable equations. He concludes with a description of Rall's model nerve cell. Because the level of mathematics increases steadily upward from Chapter Two some familiarity with differential equations and linear algebra is desirable.
Author: Carlo Laing Publisher: OUP Oxford ISBN: 0191607983 Category : Mathematics Languages : en Pages : 396
Book Description
Great interest is now being shown in computational and mathematical neuroscience, fuelled in part by the rise in computing power, the ability to record large amounts of neurophysiological data, and advances in stochastic analysis. These techniques are leading to biophysically more realistic models. It has also become clear that both neuroscientists and mathematicians profit from collaborations in this exciting research area. Graduates and researchers in computational neuroscience and stochastic systems, and neuroscientists seeking to learn more about recent advances in the modelling and analysis of noisy neural systems, will benefit from this comprehensive overview. The series of self-contained chapters, each written by experts in their field, covers key topics such as: Markov chain models for ion channel release; stochastically forced single neurons and populations of neurons; statistical methods for parameter estimation; and the numerical approximation of these stochastic models. Each chapter gives an overview of a particular topic, including its history, important results in the area, and future challenges, and the text comes complete with a jargon-busting index of acronyms to allow readers to familiarize themselves with the language used.
Author: Henry C. Tuckwell Publisher: SIAM ISBN: 9781611970159 Category : Technology & Engineering Languages : en Pages : 134
Book Description
This monograph is centered on quantitative analysis of nerve-cell behavior. The work is foundational, with many higher order problems still remaining, especially in connection with neural networks. Thoroughly addressed topics include stochastic problems in neurobiology, and the treatment of the theory of related Markov processes.
Author: Jianfeng Feng Publisher: CRC Press ISBN: 0203494466 Category : Mathematics Languages : en Pages : 649
Book Description
How does the brain work? After a century of research, we still lack a coherent view of how neurons process signals and control our activities. But as the field of computational neuroscience continues to evolve, we find that it provides a theoretical foundation and a set of technological approaches that can significantly enhance our understanding.
Author: Sonja GrĂ¼n Publisher: Springer Science & Business Media ISBN: 1441956751 Category : Medical Languages : en Pages : 447
Book Description
Solid and transparent data analysis is the most important basis for reliable interpretation of experiments. The technique of parallel spike train recordings using multi-electrode arrangements has been available for many decades now, but only recently gained wide popularity among electro physiologists. Many traditional analysis methods are based on firing rates obtained by trial-averaging, and some of the assumptions for such procedures to work can be ignored without serious consequences. The situation is different for correlation analysis, the result of which may be considerably distorted if certain critical assumptions are violated. The focus of this book is on concepts and methods of correlation analysis (synchrony, patterns, rate covariance), combined with a solid introduction into approaches for single spike trains, which represent the basis of correlations analysis. The book also emphasizes pitfalls and potential wrong interpretations of data due to violations of critical assumptions.
Author: Anthony G. Pakes Publisher: Cambridge University Press ISBN: 9780521373883 Category : Mathematics Languages : en Pages : 216
Book Description
Presented in this document is a class of deterministic models describing the dynamics of two plant species whose characteristics are common to the majority of annual plants that have a seedbank. Formulated in terms of elementary dynamical systems, these models were developed in response to four major questions on the long-term outcomes of binary mixtures of plant species: Is ultimate coexistence possible? If not, which strain will win? Does the mixture approach an equilibrium? If so, how long does the mixture take to attain it? The book gives a detailed account of model construction, analysis and application to field data obtained from long-term trials. In the particular case study modelled, the species involved are two pastural strains whose dynamics have critical agricultural and economic implications for the areas in which they are found, including North America, the Mediterranean region and Australia. This study will be valuable to researchers and students in mathematical biology and to agronomists and botanists interested in population dynamics.