Introduction to Molecular Vaccinology PDF Download

Author: Matthias Giese
Publisher: Springer
ISBN: 331925832X
Category : Medical
Languages : en
Pages : 383

View

Book Description
This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development.

Author: Matthias Giese
Publisher: Springer Science & Business Media
ISBN: 3709114195
Category : Medical
Languages : en
Pages : 460

View

Book Description
This book gives a comprehensive overview to all aspects of global molecular vaccine research. It introduces concepts of vaccine immunology and molecular vaccine development for viral, bacterial, parasitic and fungal infections. Furthermore, the broad field of research and development in molecular cancer vaccines is discussed in detail. This book is a must have for scientists and clinicians interested in new developments in molecular vaccine research and application in infections and cancer.

Author: Dr. Ramesh C.K.
Publisher: Lulu.com
ISBN: 1365707342
Category : Education
Languages : en
Pages : 178

View

Book Description
The immune system is a network of cells, tissues, and organs that work together to defend the body against attacks by "foreign" invaders. Invaders are primarily microbes such as bacteria, viruses, parasites and fungi. Because the human body provides an ideal environment for many microbes, they try to break in. It is the immune system's job to keep them out or, failing that, to seek out and destroy them. When the immune system hits the wrong target or is crippled, however, it can unleash seversl diseases, including allergy, arthritis or immune disorders.

Author: Gregg N. Milligan
Publisher: John Wiley & Sons
ISBN: 0470656166
Category : Medical
Languages : en
Pages : 404

View

Book Description
Vaccinology: An Essential Guide outlines in a clear, practical format the entire vaccine development process, from conceptualization and basic immunological principles through to clinical testing and licensing of vaccines. With an outstanding introduction to the history and practice of vaccinology, it also guides the reader through the basic science relating to host immune responses to pathogens. Covering the safety, regulatory, ethical, and economic and geographical issues that drive vaccine development and trials, it also presents vaccine delivery strategies, novel vaccine platforms (including experimental vaccines and pathogens), antigen development and selection, vaccine modelling, and the development of vaccines against emerging pathogens and agents of bioterror. There are also sections devoted to veterinary vaccines and associated regulatory processes. Vaccinology: An Essential Guide is a perfect tool for designed for undergraduate and graduate microbiologists and immunologists, as well as residents, fellows and trainees of infectious disease and vaccinology. It is also suitable for all those involved in designing and conducting clinical vaccine trials, and is the ideal companion to the larger reference book Vaccinology: Principles and Practice.

Author: Andrew P. Robinson
Publisher: Springer Science & Business Media
ISBN: 1592593992
Category : Medical
Languages : en
Pages : 411

View

Book Description
Vaccine research and development is advancing at an unprecedented pace, with an increasing emphasis on rational design based upon a fundamental und- standing of the underlying molecular mechanisms. The aim of this volume is to provide a selection of contemporary protocols that will be useful to both novice and advanced practitioner alike. The variety of procedures required to design, develop, produce, and assess a vaccine is immense and covers aspects of ch- istry, biochemistry, molecular biology, cell biology, and immunology. No single volume can hope to cover these topics exclusively. Rather, here we attempt to provide a methods sourcebook focusing on hands-on practical advice. Comp- mentary and background information may be found in other volumes in the Me- ods in Molecular Medicine series. Of particular interest are volumes on Dendritic Cell Protocols, Interleukin Protocols, Vaccine Adjuvants, and DNA Vaccines. Since the publication of the first edition of Vaccine Protocols there have been major advances, particularly in the areas of bacterial genomics, antig- specific T-cell quantification, genetic manipulation of vaccine vectors, the h- nessing of natural molecules concerned with the regulation of immune responses, and the burgeoning field of DNA vaccinology. Hence, the extensive revision of this edition with new chapters on live viral vaccine vectors, atte- ated bacterial vectors, immunomodulators, MHC-peptide tetrameric complexes, and the identification of vaccine candidates by genomic analysis. Additionally, chapters from the first edition have been updated to accommodate state-of-t- art methods in vaccinology.

Author: Sunil Thomas
Publisher: Humana
ISBN: 9781071618912
Category : Science
Languages : en
Pages : 546

View

Book Description
This volume provides a practical guide providing step-by-step methods and protocols on vaccine development and production. Divided into three volumes, Volume 3: Resources for Vaccine Development guides readers through chapters on vaccine adjuvants, vaccine vectors, production, vaccine delivery systems, vaccine bioinformatics, vaccine regulation, and intellectual property. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 3: Resources for Vaccine Development aims to be a useful practical guide to researchers to help further their study in this field.

Author: Sunil Thomas
Publisher:
ISBN: 9781493933877
Category : Vaccines
Languages : en
Pages : 873

View

Book Description

Author: Stanley A. Plotkin
Publisher: Springer Science & Business Media
ISBN: 1441913394
Category : Medical
Languages : en
Pages : 352

View

Book Description
Vaccinology, the concept of a science ranging from the study of immunology to the development and distribution of vaccines, was a word invented by Jonas Salk. This book covers the history of the methodological progress in vaccine development and to the social and ethical issues raised by vaccination. Chapters include "Jenner and the Vaccination against Smallpox," "Viral Vaccines," and "Ethical and Social Aspects of vaccines." Contributing authors include pioneers in the field, such as Samuel L. Katz and Hilary Koprowski. This history of vaccines is relatively short and many of its protagonists are still alive. This book was written by some of the chief actors in the drama whose subject matter is the conquest of epidemic disease.

Author: Sunil Thomas
Publisher: Springer Nature
ISBN: 1071618849
Category : Science
Languages : en
Pages : 702

View

Book Description
This volume provides a practical guide providing step-by-step protocol to design and develop vaccines for human diseases. Divided into three volumes, Volume 1: Vaccines for Human Diseases guides readers through an introductory section on future challenges for vaccinologists and the immunological mechanism of vaccines. Chapters focus on design of human vaccines for viral, bacterial, fungal, and parasitic diseases as well as tumor vaccines. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 1: Vaccines for Human Diseases aims to be a useful practical guide to researchers to help further their study in this field.

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309219396
Category : Science
Languages : en
Pages : 570

View

Book Description
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.