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Endogenous Interferences in Clinical Laboratory Tests

Endogenous Interferences in Clinical Laboratory Tests PDF Author: Martin H. Kroll
Publisher: Walter de Gruyter
ISBN: 3110266229
Category : Medical
Languages : en
Pages : 155

Book Description
The goal of clinical laboratories is to produce accurate information for clinical decision making in medicine. More than half of the medical decisions made depend on clinical laboratory tests. Patient safety represents an important and critical problem for laboratories. They need to assure that the information they deliver to physicians is accurate, and therefore safe for clinicians to use. Endogenous compounds can interfere with laboratory tests, decreasing accuracy and threatening patient safety. Elevated bilirubin (bilirubinemia) and elevated lipids (lipemia) are common conditions that cause significant interferences with laboratory results. Clinicians depend on laboratories to detect these endogenous interferences. Laboratories must have a means to detect these endogenous interferences, make decisions about reporting results, and evaluate their impact. Most clinical pathology books provide only an abbreviated introduction to the subject, or provide a long list of references, without the necessary foundation for evaluating their significance. Package inserts typically provide scant information. This book provides the empirical and theoretical foundation for these interferences, describes the clinical settings where they occur, and explains their evaluation and detection, allowing the laboratory to interpret the available data on interferences and make the appropriate decision to effectively report test results while protecting patient safety.

Endogenous Interferences in Clinical Laboratory Tests

Endogenous Interferences in Clinical Laboratory Tests PDF Author: Martin H. Kroll
Publisher: Walter de Gruyter
ISBN: 3110266229
Category : Medical
Languages : en
Pages : 155

Book Description
The goal of clinical laboratories is to produce accurate information for clinical decision making in medicine. More than half of the medical decisions made depend on clinical laboratory tests. Patient safety represents an important and critical problem for laboratories. They need to assure that the information they deliver to physicians is accurate, and therefore safe for clinicians to use. Endogenous compounds can interfere with laboratory tests, decreasing accuracy and threatening patient safety. Elevated bilirubin (bilirubinemia) and elevated lipids (lipemia) are common conditions that cause significant interferences with laboratory results. Clinicians depend on laboratories to detect these endogenous interferences. Laboratories must have a means to detect these endogenous interferences, make decisions about reporting results, and evaluate their impact. Most clinical pathology books provide only an abbreviated introduction to the subject, or provide a long list of references, without the necessary foundation for evaluating their significance. Package inserts typically provide scant information. This book provides the empirical and theoretical foundation for these interferences, describes the clinical settings where they occur, and explains their evaluation and detection, allowing the laboratory to interpret the available data on interferences and make the appropriate decision to effectively report test results while protecting patient safety.

Young-Type Interferences with Electrons

Young-Type Interferences with Electrons PDF Author: François Frémont
Publisher: Springer Science & Business Media
ISBN: 364238479X
Category : Science
Languages : en
Pages : 232

Book Description
Since the discovery that atomic-size particles can be described as waves, many interference experiments have been realized with electrons to demonstrate their wave behavior. In this book, after describing the different steps that led to the present knowledge, we focus on the strong link existing between photon and electron interferences, highlighting the similarities and the differences. For example, the atomic centers of a hydrogen molecule are used to mimic the slits in the Young's famous interference experiment with light. We show, however, that the basic time-dependent ionization theories that describe these Young-type electron interferences are not able to reproduce the experiment. This crucial point remains a real challenge for theoreticians in atomic collision physics.

Biotin and Other Interferences in Immunoassays

Biotin and Other Interferences in Immunoassays PDF Author: Amitava Dasgupta
Publisher: Elsevier
ISBN: 0128167416
Category : Science
Languages : en
Pages : 145

Book Description
Biotin and Other Interferences in Immunoassays: A Concise Guide is aimed at clinical laboratory scientists, medical technologists and pathologists who are often the first individuals contacted by a clinician when a laboratory test result does not correlate with clinical presentation. Research scientists working in diagnostics companies will also find this information essential. Sources of errors in non-immunoassay based methods used in clinical chemistry and toxicology laboratory are also discussed so readers can get all important information from one concise guide. This succinct, user-friendly reference provides the necessary information to address high levels of biotin in clinical laboratory results. - Discusses issues of biotin interferences and ways to avoid them for accurate clinical laboratory results - Provides sources of errors in non-immunoassay based methods used in clinical chemistry and toxicology laboratories - Highlights how to handle specimens in the lab and how to eliminate the effect of biotin in precious samples

Liability for Wrongful Interferences with Chattels

Liability for Wrongful Interferences with Chattels PDF Author: Simon Douglas
Publisher: Bloomsbury Publishing
ISBN: 1847318460
Category : Law
Languages : en
Pages : 243

Book Description
The book examines the protection of property rights in chattels through the law of torts, focusing on the four actions of conversion, detinue, trespass and negligence. Traditionally these actions have been governed by arcane divisions which have led to unnecessary complexity and arbitrariness. The principal argument made in the book is that significant developments in the modern law point towards abolition of these arcane divisions and permit the chattel torts to be understood by reference to a coherent and justifiable structure. It is argued that the only division which should be drawn in the modern chattel torts is between intentional interferences with chattels, where liability is strict, and unintentional interferences with chattels, where liability is fault based. In order to demonstrate this structure it is first argued that the actions of conversion, detinue and trespass amount, in substance, to a single cause of action which imposes strict liability for the intentional interference with another's chattel. It is then argued that the tort of negligence recognises a fault-based cause of action for the unintentional interference with another's chattel. It is further argued that this basic structure, unlike the arcane divisions which have traditionally governed this area of law, can be justified.

Filing Settlements of Patent Interferences

Filing Settlements of Patent Interferences PDF Author: United States. Congress. House. Committee on the Judiciary
Publisher:
ISBN:
Category : Patent suits
Languages : en
Pages : 48

Book Description
Committee Serial No. 30. Considers legislation to require that written notification of all patent interference settlements be filed with the Patent Office.

In the United States Patent Office Before the Examiner of Interferences

In the United States Patent Office Before the Examiner of Interferences PDF Author: Charles W. Mann
Publisher:
ISBN:
Category :
Languages : en
Pages : 240

Book Description


Election Interference

Election Interference PDF Author: Jens David Ohlin
Publisher: Cambridge University Press
ISBN: 1108861326
Category : Law
Languages : en
Pages : 233

Book Description
Russian interference in the 2016 US presidential election produced the biggest political scandal in a generation, marking the beginning of an ongoing attack on democracy. In the run-up to the 2020 election, Russia was found to have engaged in more “information operations,” a practice that has been increasingly adopted by other countries. In Election Interference, Jens David Ohlin makes the case that these operations violate international law, not as a cyberwar or a violation of sovereignty, but as a profound assault on democratic values protected by the international legal order under the rubric of self-determination. He argues that, in order to confront this new threat to democracy, countries must prohibit outsiders from participating in elections, enhance transparency on social media platforms, and punish domestic actors who solicit foreign interference. This important book should be read by anyone interested in protecting election integrity in our age of social media disinformation.

Analytical Instrumentation Handbook

Analytical Instrumentation Handbook PDF Author: Jack Cazes
Publisher: CRC Press
ISBN: 0849390397
Category : Science
Languages : en
Pages : 1066

Book Description
Compiled by the editor of Dekker's distinguished Chromatographic Science series, this reader-friendly reference is as a unique and stand-alone guide for anyone requiring clear instruction on the most frequently utilized analytical instrumentation techniques. More than just a catalog of commercially available instruments, the chapters are wri

State Responsibility for Interferences with the Freedom of Navigation in Public International Law

State Responsibility for Interferences with the Freedom of Navigation in Public International Law PDF Author: Philipp Wendel
Publisher: Springer Science & Business Media
ISBN: 3540743324
Category : Law
Languages : en
Pages : 300

Book Description
Conventions covering the law of the sea contain provisions on compensation for wrongful interferences with navigation, though they are rarely applied. This book analyses all relevant compensation provisions and compares them to the general law of state responsibility. The author discusses such issues as the responsibility of international organizations, liability for lawful conduct, and several and joint liability in public international law.

Advances in Immunoassay Technology

Advances in Immunoassay Technology PDF Author: Norman H. L. Chiu
Publisher:
ISBN: 9789535152576
Category :
Languages : en
Pages : 192

Book Description
From the basic in vitro study of a specific biomolecule to the diagnosis or prognosis of a specific disease, one of the most widely used technology is immunoassays. By using a specific antibody to recognize the biomolecule of interest, relatively high specificity can be achieved by immunoassays, such that complex biofluids (e.g. serum, urine, etc.) can be analyzed directly. In addition to the binding specificity, the other key features of immunoassays include relatively high sensitivity for the detection of antibody-antigen complexes, and a wide dynamic range for quantitation. Over the past decade, the development and applications of immunoassays have continued to grow exponentially. This book focuses on some of the latest technologies for the development of new immunoassays.