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Author: Y. Kanno Publisher: Newnes ISBN: 0444599525 Category : Science Languages : en Pages : 474
Book Description
Research on intercellular communication through gap junctions has continued to expand, and the meeting on which this book is based brought together many scientists from many different countries and disciplines. In line with the objective of the meeting, this volume focuses on the biological meaning of intercellular communication through gap junctions in various organs. The most recent up-to-date findings have been included in this extensive volume, valuable to all those interested in this rapidly expanding field.
Author: Y. Kanno Publisher: Newnes ISBN: 0444599525 Category : Science Languages : en Pages : 474
Book Description
Research on intercellular communication through gap junctions has continued to expand, and the meeting on which this book is based brought together many scientists from many different countries and disciplines. In line with the objective of the meeting, this volume focuses on the biological meaning of intercellular communication through gap junctions in various organs. The most recent up-to-date findings have been included in this extensive volume, valuable to all those interested in this rapidly expanding field.
Author: František Baluška Publisher: Springer Science & Business Media ISBN: 0387360581 Category : Science Languages : en Pages : 331
Book Description
This book covers cell-cell channels at all levels of biological organization. The purpose of this book is to document that cells are not physically separated and fully autonomous units of biological life as stated by the currently valid Cell Theory. If not the cell then some lower level unit must fulfill this role. The book deals also with the identity of this elusive unit of biological life.
Author: Gail Cardew Publisher: John Wiley & Sons ISBN: 0470515597 Category : Science Languages : en Pages : 296
Book Description
Gap junctions are key elements in communication between cells in multicellular organisms. It is clear that their activity is essential for normal embryonic development and normal function in adult organs, although the individual roles of the proteins that form the channels (connexins) are not yet fully understood. The last few years have seen considerable progress in this field and exciting new issues concerning gap junctional intercellular communication are being raised. Perturbed gap junction activity is beginning to be linked to certain pathologies, e.g. mutations in the major connexin of the heart have been found in human patients suffering from visceroatrial heterotaxia syndrome and mutations in the gene encoding another connexin have been found in patients with Charcot-Marie-Tooth disease. This book is the first to highlight the recent progress in understanding gap junction structure and to discuss the specific roles of individual connexins. It features contributions from an interdisciplinary group of experts who review the role of gap junctions in the heart, the retina and lens, the auditory system, the reproductive system, and in cell proliferation and cancer. The book will appeal to people interested in cell and molecular biology, embryonic development, neurobiology, cardiology, gynaecology and oncology.
Author: Dale J. Benos Publisher: Gulf Professional Publishing ISBN: 9780125506458 Category : Medical Languages : en Pages : 692
Book Description
Since the first gap junction protein (connexin) was cloned over a decade ago, more than a dozen connexin genes have been cloned. Consequently, a wealth of information on the molecular basis of gap junctional communication has been accumulated. This book pays tribute to this exciting era in the history of cell communication research by documenting the great strides made in this field as a result of the merging of biophysics and molecular biology, two of the most powerful approaches to studying the molecular basis of membrane channel behavior. Twenty-eight comprehensive chapters, authored by internationally recognized leaders in the field, discuss the biophysical, physiological, and molecular characteristics of cell-to-cell communication via gap junctions. Key aspects of molecular structure, formation, gating, conductance, and permeability of vertebrate and invertebrate gap junction channels are highlighted. In addition, a number of chapters focus on recent discoveries that implicate connexin mutations and alterations of gap junctional communication in the pathogenesis of several diseases, including the X-linked Charcot-Marie-Tooth demyelinating disease, some forms of inherited sensorineural deafness, malignant transformation, cardiac malformations and arrhythmia, eye lens cataract, and Chagas disease.
Author: Rudolf Werner Publisher: IOS Press ISBN: 9789051993745 Category : Gap junctions (Cell biology) Languages : en Pages : 412
Book Description
This monograph contains research articles from the leading laboratories around the world on gap junctions, the intercellular channels that allow communication between neighbouring cells. It describes the latest results in gap junctions research, the structural and functional characterization of cell-cell channels, the assembly and degradation of gap junctions, the expression and function of gap junctions in different tissues, knockout studies of gap junction genes, the regulation of connexin gene expression, and the functions of gap junctions in development and cancer. Any laboratory interested in intercellular communications and gap junction research will find this monograph an indispensable source of information and reference.
Author: David C. Spray Publisher: Springer Science & Business Media ISBN: 3662219352 Category : Medical Languages : en Pages : 321
Book Description
This book deals with the types of gap junction proteins (connexins) and their distribution within the nervous system, the physiological properties of channels formed of each connexin, and the role of gap junction channels in functions of normal and pathological brain and peripheral nerve. Although glial tissue is emphasized, additional groups of chapters deal with neurons in the central nervous system and with the retina.
Author: A.W. Robards Publisher: Springer Science & Business Media ISBN: 3642839711 Category : Science Languages : en Pages : 282
Book Description
Intracellular junctions provide routes for direct cell-to-cell signalling in both plants and animals. The present volume treats the parallels and differences between such junctions in animals and plants and discusses the most recent methods of examining the physiological functions and regulation of intracellular communication. Strong evidence of both molecular as well as functional simi§ larities between plasmodesmata and gap junctions is increasing. Even more interesting is the discovery that animal gap junction proteins cross-react immunologically with some proteins in plant cells. Thus the molecular construction and function of these crucially important ultrastructural cell components is now open to a concerted research effort to understand how cells, both plant and animal, facilitate and regulate intercellular transport.
Author: J.E. Hall Publisher: Elsevier ISBN: 0444599843 Category : Science Languages : en Pages : 356
Book Description
Gap junctions are present in nearly all tissues, regardless of their embronic origin and have long been of great interest to scientists from many different disciplines. The international meeting on which this book is based brought together 157 scientists from 12 countries and almost as many scientific disciplines. The papers presented at the meeting were reviewed and updated prior to publication in this book. The seven parts of the book progress from general topics to the more specific ones (role of gap junctions in various tissues, regulation and biochemistry, and cancer).
Author: Y. Kanno
Author: Y. Kanno
Author: František Baluška
Author: Bruce Alberts
Author: Gail Cardew
Author: Dale J. Benos
Author: Rudolf Werner
Author: David C. Spray
Author: Walmor C. De Mello
Author: A.W. Robards
Author: J.E. Hall