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Author: John Cann Publisher: Elsevier ISBN: 032315865X Category : Science Languages : en Pages : 262
Book Description
Interacting Macromolecules: The Theory and Practice of Their Electrophoresis, Ultracentrifugation, and Chromatography reviews advances in theory and practice concerning the electrophoresis, ultracentrifugation, and chromatography of interacting macromolecules. The principles of mass transport of non-interacting systems are discussed, along with the weak electrolyte moving-boundary theory and analytical solution of approximate transport equations for certain types of interactions. Computer computations on ligand-mediated association-dissociation reactions are also presented. This book is comprised of six chapters and begins with a survey of the principles of electrophoresis and ultracentrifugation of non-reacting systems before proceeding with a detailed treatment of the mass transport of reversibly reacting macromolecules. A conservation equation is derived for a solution containing a single macromolecular ion. The following chapters explore the weak-electrolyte moving-boundary theory; the analytical Solution of approximate conservation equations; and numerical solution of exact conservation equations. The formulation of the numerical computation for ligand-mediated association-dissociation reactions is described, together with a code for sedimentation calculations. The final chapter summarizes the procedures and precautions required to assure accurate interpretation of sedimentation and electrophoretic patterns in terms of the thermodynamic and molecular parameters characterizing the reactions exhibited by biological macromolecules. The more common analytical applications of ultracentrifugation, electrophoresis, and chromatography are also outlined. This monograph is intended for molecular biologists and graduate students.
Author: John Cann Publisher: Elsevier ISBN: 032315865X Category : Science Languages : en Pages : 262
Book Description
Interacting Macromolecules: The Theory and Practice of Their Electrophoresis, Ultracentrifugation, and Chromatography reviews advances in theory and practice concerning the electrophoresis, ultracentrifugation, and chromatography of interacting macromolecules. The principles of mass transport of non-interacting systems are discussed, along with the weak electrolyte moving-boundary theory and analytical solution of approximate transport equations for certain types of interactions. Computer computations on ligand-mediated association-dissociation reactions are also presented. This book is comprised of six chapters and begins with a survey of the principles of electrophoresis and ultracentrifugation of non-reacting systems before proceeding with a detailed treatment of the mass transport of reversibly reacting macromolecules. A conservation equation is derived for a solution containing a single macromolecular ion. The following chapters explore the weak-electrolyte moving-boundary theory; the analytical Solution of approximate conservation equations; and numerical solution of exact conservation equations. The formulation of the numerical computation for ligand-mediated association-dissociation reactions is described, together with a code for sedimentation calculations. The final chapter summarizes the procedures and precautions required to assure accurate interpretation of sedimentation and electrophoretic patterns in terms of the thermodynamic and molecular parameters characterizing the reactions exhibited by biological macromolecules. The more common analytical applications of ultracentrifugation, electrophoresis, and chromatography are also outlined. This monograph is intended for molecular biologists and graduate students.
Author: Alberto Ciferri Publisher: John Wiley & Sons ISBN: 1118165845 Category : Science Languages : en Pages : 723
Book Description
This book is a comprehensive study of the subject of ionic interactions in macromolecules. The first parts of the book review and analyze the conventional treatments of fixed charges (e.g. in polyelectrolytes and polyampholytes), including screening and condensation by mobile ions. The interaction of ions with less polar sites on the macromolecule (e.g. amide bonds), and the origin of the lyotropic effects (focusing on binding versus condensation) will also be extensively addressed. The book also explores complex micellar organizations involving charged macromolecules (e.g. DNA) and low-molecular-weight ampholytes and strong protein associations. The resulting structures are relevant to a variety of functional biological systems and synthetic analogs. The contribution of electrostatic and hydrophobic interaction to the stability of proteins and other supramolecular structures will also be analyzed. There are chapters on applications such as deionization and cosmetic formulation. This 21-chapter book is divided into three sections: Fundamentals Mixed Interactions Functions and Applications
Author: Werner Kunz Publisher: World Scientific ISBN: 9814271586 Category : Medical Languages : en Pages : 347
Book Description
Specific ion effects are important in numerous fields of science and technology. This book summarizes the main ideas that came up over the years. It presents the efforts of theoreticians and supports it by the experimental results stemming from various techniques.
Author: Westhof Publisher: CRC Press ISBN: 9780849375705 Category : Science Languages : en Pages : 492
Book Description
Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging. Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists.
Author: Ana Cecília A. Roque Publisher: Methods in Molecular Biology ISBN: Category : Medical Languages : en Pages : 316
Book Description
In this authoritative book, experts in the field highlight the main principles and methodologies currently utilized in the study of molecular interactions between compounds. This is as an ideal guide to those striving to further our knowledge of medicines.
Author: Chin Han Chan Publisher: CRC Press ISBN: 148223419X Category : Science Languages : en Pages : 636
Book Description
Knowledge of thermodynamics is a necessary tool for describing and understanding the physical behavior of new polymers and polymer blends, for instance, compatibility of components, rheological properties, morphological features, and mechanical properties. This book summarizes in a fairly comprehensive manner the recent technical research accomplis
Author: John Cann
Author: John Cann
Author: Alberto Ciferri
Author: E. Tsuchida
Author: 
Author: Werner Kunz
Author: E. Tsuchida
Author: Westhof
Author: Ana Cecília A. Roque
Author: Chin Han Chan
Author: C. Helene