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Integration of Microfluidics and Multimodal Optics for Translational Bioanalytics

Integration of Microfluidics and Multimodal Optics for Translational Bioanalytics PDF Author: Daniel Migliozzi
Publisher:
ISBN:
Category :
Languages : en
Pages : 127

Book Description
Mots-clés de l'auteur: translational bioanalytics ; multimodal imaging ; microfluidics ; high-content ; drug screening ; tumor diagnostics ; dielectric microsphere ; multiplexing ; cancer biomarker ; immunophenotyping.

Integration of Microfluidics and Multimodal Optics for Translational Bioanalytics

Integration of Microfluidics and Multimodal Optics for Translational Bioanalytics PDF Author: Daniel Migliozzi
Publisher:
ISBN:
Category :
Languages : en
Pages : 127

Book Description
Mots-clés de l'auteur: translational bioanalytics ; multimodal imaging ; microfluidics ; high-content ; drug screening ; tumor diagnostics ; dielectric microsphere ; multiplexing ; cancer biomarker ; immunophenotyping.

Nanoporous Gold

Nanoporous Gold PDF Author: Arne Wittstock
Publisher: Royal Society of Chemistry
ISBN: 184973528X
Category : Technology & Engineering
Languages : en
Pages : 265

Book Description
High-surface-area materials have recently attracted significant interest due to potential applications in various fields such as electrochemistry and catalysis, gas-phase catalysis, optics, sensors and actuators, energy harvesting and storage. In contrast to classical materials the properties of high-surface-area materials are no longer determined by their bulk, but by their nanoscale architecture. Nanoporous gold (np-Au) represents the fascinating class of mesoporous metals that have been intensively investigated in recent years. The current interest and the increasing number of scientific publications show that np-Au by itself is an outstanding nano-material that justifies a book devoted to all aspects of its properties and applications. The resulting publication is a discussion of this unique nano-material and is an accessible and comprehensive introduction to the field. The book provides a broad, multi-disciplinary platform to learn more about the properties of nanoporous gold from an inter-disciplinary perspective. It starts with an introduction and overview of state-of-the-art applications and techniques characterizing this material and its applications. It then covers the progress in research within the last years. The chapters are in-depth overviews written by the world's leading scientists in the particular field. Each chapter covers one technique or application so that the reader can easily target their favoured topic and will get the latest and state-of-the-art information in the field.

Neural Network Models of Cognition

Neural Network Models of Cognition PDF Author: J.W. Donahoe
Publisher: Elsevier
ISBN: 0080537367
Category : Computers
Languages : en
Pages : 601

Book Description
This internationally authored volume presents major findings, concepts, and methods of behavioral neuroscience coordinated with their simulation via neural networks. A central theme is that biobehaviorally constrained simulations provide a rigorous means to explore the implications of relatively simple processes for the understanding of cognition (complex behavior). Neural networks are held to serve the same function for behavioral neuroscience as population genetics for evolutionary science. The volume is divided into six sections, each of which includes both experimental and simulation research: (1) neurodevelopment and genetic algorithms, (2) synaptic plasticity (LTP), (3) sensory/hippocampal systems, (4) motor systems, (5) plasticity in large neural systems (reinforcement learning), and (6) neural imaging and language. The volume also includes an integrated reference section and a comprehensive index.

Microfluidic Devices for Biomedical Applications

Microfluidic Devices for Biomedical Applications PDF Author: Xiujun James Li
Publisher: Woodhead Publishing
ISBN: 9780857096975
Category : Technology & Engineering
Languages : en
Pages : 0

Book Description
Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications. The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries.

Microfluidics for Single-Cell Analysis

Microfluidics for Single-Cell Analysis PDF Author: Jin-Ming Lin
Publisher: Springer Nature
ISBN: 9813297298
Category : Science
Languages : en
Pages : 261

Book Description
This book summarizes the various microfluidic-based approaches for single-cell capture, isolation, manipulation, culture and observation, lysis, and analysis. Single-cell analysis reveals the heterogeneities in morphology, functions, composition, and genetic performance of seemingly identical cells, and advances in single-cell analysis can overcome the difficulties arising due to cell heterogeneity in the diagnostics for a targeted model of disease. This book provides a detailed review of the state-of-the-art techniques presenting the pros and cons of each of these methods. It also offers lessons learned and tips from front-line investigators to help researchers overcome bottlenecks in their own studies. Highlighting a number of techniques, such as microfluidic droplet techniques, combined microfluidics-mass-spectrometry systems, and nanochannel sampling, it describes in detail a new microfluidic chip-based live single-cell extractor (LSCE) developed in the editor’s laboratory, which opens up new avenues to use open microfluidics in single-cell extraction, single-cell mass spectrometric analysis, single-cell adhesion analysis and subcellular operations. Serving as both an elementary introduction and advanced guidebook, this book interests and inspires scholars and students who are currently studying or wish to study microfluidics-based cell analysis methods.

Microfluidics and Lab-on-a-Chip

Microfluidics and Lab-on-a-Chip PDF Author: Andreas Manz
Publisher: Royal Society of Chemistry
ISBN: 1782628339
Category : Science
Languages : en
Pages : 307

Book Description
Responding to the need for an affordable, easy-to-read textbook that introduces microfluidics to undergraduate and postgraduate students, this concise book will provide a broad overview of the important theoretical and practical aspects of microfluidics and lab-on-a-chip, as well as its applications.

Microscale Acoustofluidics

Microscale Acoustofluidics PDF Author: Thomas Laurell
Publisher: Royal Society of Chemistry
ISBN: 1849737061
Category : Technology & Engineering
Languages : en
Pages : 593

Book Description
The manipulation of cells and microparticles within microfluidic systems using external forces is valuable for many microscale analytical and bioanalytical applications. Acoustofluidics is the ultrasound-based external forcing of microparticles with microfluidic systems. It has gained much interest because it allows for the simple label-free separation of microparticles based on their mechanical properties without affecting the microparticles themselves. Microscale Acoustofluidics provides an introduction to the field providing the background to the fundamental physics including chapters on governing equations in microfluidics and perturbation theory and ultrasound resonances, acoustic radiation force on small particles, continuum mechanics for ultrasonic particle manipulation, and piezoelectricity and application to the excitation of acoustic fields for ultrasonic particle manipulation. The book also provides information on the design and characterization of ultrasonic particle manipulation devices as well as applications in acoustic trapping and immunoassays. Written by leading experts in the field, the book will appeal to postgraduate students and researchers interested in microfluidics and lab-on-a-chip applications.

Nanoscience And Technology: A Collection Of Reviews From Nature Journals

Nanoscience And Technology: A Collection Of Reviews From Nature Journals PDF Author: Peter Rodgers
Publisher: World Scientific
ISBN: 9814466867
Category : Technology & Engineering
Languages : en
Pages : 367

Book Description
This book contains 35 review articles on nanoscience and nanotechnology that were first published in Nature Nanotechnology, Nature Materials and a number of other Nature journals. The articles are all written by leading authorities in their field and cover a wide range of areas in nanoscience and technology, from basic research (such as single-molecule devices and new materials) through to applications (in, for example, nanomedicine and data storage).

Cell Analysis on Microfluidics

Cell Analysis on Microfluidics PDF Author: Jin-Ming Lin
Publisher: Springer
ISBN: 9811053944
Category : Science
Languages : en
Pages : 435

Book Description
This book presents a detailed overview of the design, formatting, application, and development of microfluidic chips in the context of cell biology research, enumerating each element involved in microfluidics-based cell analysis, discussing its history, status quo, and future prospects, It also offers an extensive review of the research completed in the past decade, including numerous color figures. The individual chapters are based on the respective authors' studies and experiences, providing tips from the frontline to help researchers overcome bottlenecks in their own work. It highlights a number of cutting-edge techniques, such as 3D cell culture, microfluidic droplet technique, and microfluidic chip-mass spectrometry interfaces, offering a first-hand impression of the latest trends in the field and suggesting new research directions. Serving as both an elementary introduction and advanced guidebook, the book interests and inspires scholars and students who are currently studying microfluidics-based cell analysis methods as well as those who wish to do so.

Microfluidics for Cells and Other Organisms

Microfluidics for Cells and Other Organisms PDF Author: Danny van Noort
Publisher: MDPI
ISBN: 3039215620
Category : Technology & Engineering
Languages : en
Pages : 200

Book Description
Microfluidics-based devices play an important role in creating realistic microenvironments in which cell cultures can thrive. They can, for example, be used to monitor drug toxicity and perform medical diagnostics, and be in a static-, perfusion- or droplet-based device. They can also be used to study cell-cell, cell-matrix or cell-surface interactions. Cells can be either single cells, 3D cell cultures or co-cultures. Other organisms could include bacteria, zebra fish embryo, C. elegans, to name a few.