Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Neural Control of Renal Function PDF full book. Access full book title Neural Control of Renal Function by Ulla Kopp. Download full books in PDF and EPUB format.
Author: Ulla Kopp Publisher: Morgan & Claypool Publishers ISBN: 1615042318 Category : Medical Languages : en Pages : 99
Book Description
The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Activation of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension. Table of Contents: Part I: Efferent Renal Sympathetic Nerves / Introduction / Neuroanatomy / Neural Control of Renal Hemodynamics / Neural Control of Renal Tubular Function / Neural Control of Renin Secretion Rate / Part II: Afferent Renal Sensory Nerves / Introduction / Neuroanatomy / Renorenal Reflexes / Mechanisms Involved in the Activation of Afferent Renal Sensory Nerves / Part III: Pathophysiological States / Efferent Renal Sympathetic Nerves / Afferent Renal Sensory Nerves / Conclusions / References
Author: Ulla Kopp Publisher: Morgan & Claypool Publishers ISBN: 1615042318 Category : Medical Languages : en Pages : 99
Book Description
The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of α1-adrenoceptors and increase renin secretion rate by activation of β1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic tissue of a magnitude that may occur during increased urine flow rate. Activation of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension. Table of Contents: Part I: Efferent Renal Sympathetic Nerves / Introduction / Neuroanatomy / Neural Control of Renal Hemodynamics / Neural Control of Renal Tubular Function / Neural Control of Renin Secretion Rate / Part II: Afferent Renal Sensory Nerves / Introduction / Neuroanatomy / Renorenal Reflexes / Mechanisms Involved in the Activation of Afferent Renal Sensory Nerves / Part III: Pathophysiological States / Efferent Renal Sympathetic Nerves / Afferent Renal Sensory Nerves / Conclusions / References
Author: Shahrokh F. Shariat Publisher: Springer ISBN: 1493915010 Category : Medical Languages : en Pages : 206
Book Description
Upper Tract Urothelial Carcinoma represents the first book of its kind to be dedicated solely to UTUC. It's aim is to improve understanding and eventually care of a disease that is greatly understudied and underappreciated, yet commonly dealt with by many medical and urologic oncologists. The volume features new data regarding genetic susceptibility, gene expression studies and causative factors; contemporary concepts and controversies regarding diagnosis and staging of UTUC; prediction tools and their value in treatment decisions within each disease stage and patient selection and treatment options such as endoscopic management, distal ureterectomy, radical nephroureterectomy and chemotherapy. Up-to-date information regarding boundaries of surgical resection, indication and extent of lymphadenectomy is covered as well as the role of perioperative/neoadjuvant chemotherapy in patients with high-risk UTUC. Upper Tract Urothelial Carcinoma will be of great value to all Urologists, Medical Oncologists and fellows in Urologic Oncology as well as upper level residents in training in Urology and Medical Oncology.
Author: Laura D. Byham-Gray Publisher: Springer Science & Business Media ISBN: 1627036857 Category : Medical Languages : en Pages : 495
Book Description
Nutrition in Kidney Disease, Second Edition addresses the relationships between nutrition and (1) normal kidney function and disease, (2) the progressiveness of chronic kidney disease (CKD) and strategies to prevent further compromise, and (3) the treatment and management of kidney failure especially during medical crises, such as acute kidney injury and its consequent nutritional therapies (e.g., enteral and parenteral nutrition). Demographic patterns, trends and outcomes in the current health care systems are explored in the United States and abroad. Disease prevention and management are presented over the entire lifespan, beginning with pregnancy, followed by infancy, childhood, adolescence, and adulthood, concluding with the elder years. Foundations for clinical practice are established by devoting a complete section towards conducting a comprehensive nutritional assessment, comprising of anthropometric, biochemical, clinical, physical parameters and psychosocial concerns unique to the kidney disease population. Nutritional therapy is also discussed across the spectrum of kidney disease, and pertinent aspects critical to successful management of disorders and conditions, such as bone disease, obesity, and nephrotic syndrome are explored. Nutrition in Kidney Disease, Second edition highlights cutting edge research in regards to exercise and functional outcomes, malnutrition and the inflammatory response, experimental therapies, and the use of complementary and alternative medicine, with a special emphasis on relevant preventative strategies.
Author: Sarah Bronwen Horton Publisher: Univ of California Press ISBN: 0520283279 Category : Business & Economics Languages : en Pages : 264
Book Description
"They Leave Their Kidneys in the Fields takes the reader on an ethnographic tour of the melon and corn harvesting fields in California's Central Valley to understand why farmworkers die at work each summer. Laden with captivating detail of farmworkers' daily work and home lives, Horton examines how U.S. immigration policy and the historic exclusion of farmworkers from the promises of liberalism has made migrant farmworkers what she calls 'exceptional workers.' She explores the deeply intertwined political, legal, and social factors that place Latino migrants at particular risk of illness and injury in the fields, as well as the patchwork of health care, disability, and Social Security policies that provide them little succor when they become sick or grow old. The book takes an in-depth look at the work risks faced by migrants at all stages of life: as teens, in their middle-age, and ultimately as elderly workers. By following the lives of a core group of farmworkers over nearly a decade, Horton provides a searing portrait of how their precarious immigration and work statuses culminate in preventable morbidity and premature death"--Provided by publisher.
Author: Marlies Elger Publisher: Springer ISBN: Category : Medical Languages : en Pages : 116
Book Description
Knowledge of the architecture of the renal glomerulus is a prerequisite for understanding both glomerular function and pathology. Glomerular filtration depends on comparably high intracapillary hydrostatic pressures. These high pressures must be balanced by commensurate counterforces to maintain structural integrity. Elevated pressures can damage the glomerulus. The "window" for pressures high enough for effective filtration and yet tolerable to the glomerulus is narrow. Precise regulation is therefore necessary to keep intraglomerular pressure within an appropriate range. This study provides a comprehensive description of the glomerular arterioles, which are the vessels primarily responsible for the regulation of intraglomerular pressures. It thereby describes the structures which may be presumed to generate counterforces needed to assure structural stability. The arterioles are closely associated with the supporting system comprised of the intra- and extraglomerular mesangium. The extraglomerular mesangium forms a spider-like clamp providing a mechanical interconnection of all components of the vascular pole. At the same time, it may act as a tension receptor, i.e. as a sensor of intraglomerular pressures. Due to its intimate relationship to the macula densa, the extraglomerular mesangium receives information on the distal solute delivery and therefore may act as the integrative center within the juxtaglomerular apparatus. The close spatial association between the afferent and efferent arterioles at the vascular pole suggests a direct regulatory interaction between both arterioles. In addition, the specific wall structure of the efferent arteriole exhibiting the features of a shear stress receptor suggests new pathways for feedback regulation of glomerular hemodynamics.
Author: Anita T. Layton Publisher: Springer ISBN: 364227367X Category : Mathematics Languages : en Pages : 225
Book Description
With the availability of high speed computers and advances in computational techniques, the application of mathematical modeling to biological systems is expanding. This comprehensive and richly illustrated volume provides up-to-date, wide-ranging material on the mathematical modeling of kidney physiology, including clinical data analysis and practice exercises. Basic concepts and modeling techniques introduced in this volume can be applied to other areas (or organs) of physiology. The models presented describe the main homeostatic functions performed by the kidney, including blood filtration, excretion of water and salt, maintenance of electrolyte balance and regulation of blood pressure. Each chapter includes an introduction to the basic relevant physiology, a derivation of the essential conservation equations and then a discussion of a series of mathematical models, with increasing level of complexity. This volume will be of interest to biological and mathematical scientists, as well as physiologists and nephrologists, who would like an introduction to mathematical techniques that can be applied to renal transport and function. The material is written for students who have had college-level calculus, but can be used in modeling courses in applied mathematics at all levels through early graduate courses.
Author: John F. Ash Publisher: McGraw Hill Professional ISBN: 0071813705 Category : Science Languages : en Pages : 313
Book Description
Get the BIG PICTURE of Histology – and zero-in on what you really need to know to ace the course and board exams! 400 FULL-COLOR ILLUSTRATIONS Medical Histology: The Big Picture is a different kind of study tool. With an emphasis on what you “need to know” versus “what’s nice to know”, and featuring more than 400 full-color illustrations and micrographs, it offers a focused, streamlined overview of human histology. You’ll find a succinct, user-friendly presentation designed to make even the most complex concepts understandable in a short amount of time. With just right balance of information to give you the edge at exam time, this unique combination text and atlas features: An efficient, study-enhancing design consisting of text on the left-hand page and related illustrations on the right-hand page – allowing you to grasp individual principles, one concept at a time The inclusion of detail, often clinical in nature, that clarifies the link between the structural and functional applications of histology Review questions and answers at the end of each chapter A complete final exam at the end of the book Icons that indicate high-yield, clinically relevant concepts Key Structures highlighted when they first appear to indicate their importance More than 400 full-color illustrations and micrographs depicting essential histology Concise, easy-to-remember bulleted text
Author: Josefine Neuendorf Publisher: Springer Nature ISBN: 3030159116 Category : Medical Languages : en Pages : 252
Book Description
This book is a comprehensive resource and up-to-date description of all urinary sediment constituents which are presented in bright-field mode and in phase-contrast mode. Thanks to numerous detailed images of urinary sediment constituents, the reader is able to easily compare what they view microscopically with high-resolution photographs and short films. The book is also designed to aid the identification of rare urine constituents in their native state without prior staining. It also features guidance on how set-up a microscope , microscopy techniques, and preanalytics. Exercises focused on microscopic analysis and diagnosis and a urinary sediment quiz reinforce key concepts to aid learning. Urine Sediment provides a practically applicable guide to the recognition of urinary sediment constituents. It is therefore a critical resource for trainees and experienced practitioners in urology, nephrology, gynecology and general practice who need to be able to accurately and quickly identify urine sediment constituents.
Author: Ulla Kopp
Author: Ulla Kopp
Author: Lindsay Biga
Author: J. Gordon Betts
Author: Shahrokh F. Shariat
Author: Laura D. Byham-Gray
Author: Sarah Bronwen Horton
Author: Marlies Elger
Author: Anita T. Layton
Author: John F. Ash
Author: Josefine Neuendorf